Alexander T. Sandhu

ORCID: 0000-0003-3208-1143
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About
Contact & Profiles
Research Areas
  • Heart Failure Treatment and Management
  • Cardiovascular Function and Risk Factors
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiac pacing and defibrillation studies
  • Cardiac Imaging and Diagnostics
  • Healthcare Policy and Management
  • Medication Adherence and Compliance
  • Diabetes Treatment and Management
  • Atrial Fibrillation Management and Outcomes
  • Primary Care and Health Outcomes
  • Mechanical Circulatory Support Devices
  • Cardiac Health and Mental Health
  • Chronic Disease Management Strategies
  • Acute Myocardial Infarction Research
  • Potassium and Related Disorders
  • Pharmaceutical Economics and Policy
  • Radiation Dose and Imaging
  • Transplantation: Methods and Outcomes
  • Emergency and Acute Care Studies
  • Cardiac Structural Anomalies and Repair
  • Healthcare cost, quality, practices
  • Cardiac, Anesthesia and Surgical Outcomes
  • Advanced X-ray and CT Imaging
  • Nutrition and Health in Aging
  • Telemedicine and Telehealth Implementation

Stanford University
2016-2025

VA Palo Alto Health Care System
2015-2025

Stanford Health Care
2024-2025

Veterans Health Administration
2023-2025

Cardiovascular Institute of the South
2021-2024

Palo Alto University
2023-2024

Stanford Medicine
2021-2023

Acumen (United States)
2020-2023

Palo Alto Veterans Institute for Research
2021-2023

Cleveland Clinic
2023

Coronary artery disease (CAD), the most common manifestation of cardiovascular disease, remains cause mortality in United States. Risk assessment is key for primary prevention coronary events and calcium (CAC) scoring using computed tomography (CT) one such non-invasive tool. Despite proven clinical value CAC, current practice implementation CAC has limitations as lack insurance coverage test, need capital-intensive CT machines, specialized imaging protocols, accredited 3D labs analysis...

10.1038/s41746-021-00460-1 article EN cc-by npj Digital Medicine 2021-06-01

Background: Coronary artery calcium (CAC) can be identified on nongated chest computed tomography (CT) scans, but this finding is not consistently incorporated into care. A deep learning algorithm enables opportunistic CAC screening of CT scans. Our objective was to evaluate the effect notifying clinicians and patients incidental statin initiation. Methods: NOTIFY-1 (Incidental Calcification Quality Improvement Project) a randomized quality improvement project in Stanford Health Care System....

10.1161/circulationaha.122.062746 article EN Circulation 2022-11-07

<h3>Importance</h3> In the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure (DAPA-HF) trial, dapagliflozin was shown to reduce cardiovascular mortality hospitalizations due heart failure while improving patient-reported health status. However, cost-effectiveness adding therapy standard care (SOC) is unknown. <h3>Objective</h3> To estimate among patients with chronic reduced ejection fraction (HFrEF). <h3>Design, Setting, Participants</h3> This Markov cohort model used...

10.1001/jamacardio.2021.1437 article EN JAMA Cardiology 2021-05-26

In the Empagliflozin Outcome Trial in Patients With Chronic Heart Failure Preserved Ejection Fraction (EMPEROR-Preserved), empagliflozin significantly reduced hospitalizations for heart failure while improving patient-reported health status compared with placebo. The long-term cost-effectiveness of among patients who have preserved ejection fraction (HFpEF) remains unclear.To estimate HFpEF.This analysis performed from October 2021 to April 2022 included a Markov model using estimates...

10.1001/jamainternmed.2022.5010 article EN JAMA Internal Medicine 2022-11-07

Sacubitril-valsartan therapy reduces cardiovascular mortality compared with enalapril in patients heart failure reduced ejection fraction.To evaluate the cost-effectiveness of sacubitril-valsartan versus angiotensin-converting enzyme inhibitor chronic failure.Markov decision model.Clinical trials, observational analyses, reimbursement data from Centers for Medicare & Medicaid Services, drug pricing databases, and Disease Control Prevention life tables.Patients at an average age 64 years, New...

10.7326/m16-0057 article EN Annals of Internal Medicine 2016-08-29

Noninvasive testing and coronary angiography are used to evaluate patients who present the emergency department (ED) with chest pain, but their effects on outcomes uncertain.To determine whether cardiovascular testing-noninvasive imaging or angiography-is associated changes in rates of revascularization acute myocardial infarction (AMI) admission ED pain without initial findings ischemia.This retrospective cohort analysis weekday (Monday-Thursday) vs weekend (Friday-Sunday) presentation as...

10.1001/jamainternmed.2017.2432 article EN JAMA Internal Medicine 2017-06-27

Early heart failure (HF) recognition can reduce morbidity, yet HF is often initially diagnosed only after a patient clinically worsens. We sought to identify characteristics that predict diagnosis in the acute care setting versus outpatient setting.We estimated proportion of incident (inpatient hospital or emergency department) based on diagnostic codes from claims database covering commercial insurance and Medicare Advantage between 2003 2019. After excluding new-onset potentially caused by...

10.1161/circheartfailure.121.008538 article EN Circulation Heart Failure 2021-07-27

Clinicians typically estimate heart failure health status using the New York Heart Association Class, which is often discordant with patient-reported status. It unknown whether collecting improves accuracy of clinician assessments.

10.1161/circheartfailure.122.010280 article EN Circulation Heart Failure 2022-11-05
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