A5108049986- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Glioma Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Rocket and propulsion systems research
- Stress Responses and Cortisol
- Treatment of Major Depression
- Combustion and flame dynamics
- Thyroid Disorders and Treatments
- Neuroendocrine regulation and behavior
- Industrial Vision Systems and Defect Detection
- Fluid Dynamics and Heat Transfer
- Advanced Fiber Optic Sensors
- Ophthalmology and Eye Disorders
- Iron and Steelmaking Processes
- Schizophrenia research and treatment
- Color Science and Applications
- Cancer, Hypoxia, and Metabolism
- Adrenal Hormones and Disorders
- Metabolomics and Mass Spectrometry Studies
- Innovative Teaching and Learning Methods
- Neuroendocrine Tumor Research Advances
- Advanced Combustion Engine Technologies
- Reflective Practices in Education
- Plasmonic and Surface Plasmon Research
Yonsei University
2007-2025
Severance Hospital
1995-2025
Inje University Ilsan Paik Hospital
2024
Korea Institute of Brain Science
2020
University of Missouri
2016
Korea University
2010
Thyrogen, a recombinant human thyroid-stimulating hormone (rhTSH), has short half-life in the bloodstream, which necessitates multiple doses during treatment. Therefore, we developed new long-acting rhTSH using anti-serum albumin Fab-associated (SAFA) technology to validate its biological activity through vitro assays, pharmacokinetic (PK) studies healthy mice, and pharmacodynamics (PD) TSH-suppressed mouse model.SAFA-TSH was produced Chinese hamster ovary expression system. To verify...
BackgroundThis study aimed to determine the value of 68Ga-DOTATOC positron emission tomography/computed tomography (PET/CT) in localizing adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas. MethodsIn this retrospective cohort study, we enrolled 30 patients with Cushing's disease and positive ACTH immunoreactivity. All underwent PET/CT magnetic resonance imaging (MRI) before transsphenoidal adenomectomy. ResultsTwenty-five showed uptake their glands on PET/CT. Median age,...
This study was designed to investigate changes in health-related quality of life (HRQoL) patients with acromegaly Korea after medical treatment octreotide LAR using the validated Korean version questionnaire (AcroQoL).A prospective, open-label, single-arm study.11 tertiary centres Korea.58 (aged 21-72 years) who were newly diagnosed between 2009 and 2012 prescribed 20 mg at time enrolment. During 24 weeks observation, AcroQoL survey questionnaires measurement growth hormone insulin-like...
Wave propagation characteristics of apertures were analyzed to explain the light transmission metallic nanoapertures. Based on Maxwell’s equations, wave dispersion relations modes in nanoapertures derived. The resonance frequency shift aperture and variation spot size are explained with relations. relationship between near-field far-field power throughput is also shown mode change predicted by
Students with disabilities often struggle in science and underperform this important content area when compared to their typical peers. Unfortunately, many special educators have had little preparation develop knowledge or skills methods for teaching science. Despite lack of knowledge, are solely responsible students resource settings self-contained classrooms; while inclusive settings, may be called on coteach consult. Given increased role content, experience anxiety about own knowledge....
Background: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment costly. Moreover, some patients are unresponsive to treatment. Hence, there increasing efforts develop new drugs with improved effectiveness for this disease. BIM23B065 novel chimeric molecule that acts on both somatostatin dopamine receptors. This study aimed investigate the effects of compared those receptor analog agonist. Methods: The proliferation, GH...
Background: Oxytocin (OXT) has been reported to act as a growth regulator in various tumor cells.However, there is paucity of data on the influence OXT cell proliferation corticotroph adenomas.This study aimed examine whether affects pituitary lines (AtT20 and GH3 cells) with focus adenoma cells.Methods: Reverse transcription polymerase chain reaction enzyme-linked immunosorbent assay were conducted AtT20 cells confirm effects hormonal activity; flow cytometry was used assess changes cycle...
The purpose of this study was to examine whether people with ultra-high risk for psychosis showed biases as well deficits in facial emotional recognition which were well-established findings schizophrenia. Forty-five ultra- high (UHR) psychosis, 30 first-episode (FE) schizophrenia and 40 healthy controls asked recognize the category photographs. stimuli selected from standard photographs Japanese Caucasian Facial Expressions Emotion (JACFEE) depicting basic emotions happiness, disgust,...
In this paper, we investigate video quality on various LCD monitors. There exists a large variance in among Due to unavoidable monitors, there has been concern about the stability and repeatability of subjective objective testing for We performed DSCQS method compare ratings 5 The experimental results show that correlation coefficients DMOS's with respect each monitor are acceptably high. Thus, it may be possible develop models measurement physical parameters such as color temperature,...
Background Danshen has been widely used in oriental medicine to improve body function. The purpose of this study is investigate the effect water-soluble extract (DE) on weight loss and activation proteins involved mitochondrial biogenesis brown adipose tissue (BAT) obese mice. Methods BAT was isolated from 7-week-old male Sprague-Dawley rats, expression related confirmed both preadipocytes mature adipocytes treated with DE. For vivo study, low-density lipoprotein receptor knock out mice were...