A5060925577- Cervical Cancer and HPV Research
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Head and Neck Cancer Studies
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Economic and Financial Impacts of Cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- Cancer Cells and Metastasis
- Breast Cancer Treatment Studies
- Health Systems, Economic Evaluations, Quality of Life
- PARP inhibition in cancer therapy
- Viral-associated cancers and disorders
- Oral Health Pathology and Treatment
- Lymphoma Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Epigenetics and DNA Methylation
- Chronic Lymphocytic Leukemia Research
- Cancer Diagnosis and Treatment
- Global Public Health Policies and Epidemiology
- Uterine Myomas and Treatments
- Healthcare Systems and Reforms
- Breast Lesions and Carcinomas
Bhubaneswar Borooah Cancer Institute
2016-2025
All India Institute of Medical Sciences
2023
Tata Memorial Hospital
2022
Indian Institute of Technology Guwahati
2017
National Cancer Registry
2015
Gauhati University
2015
The rising economic burden of cancer on patients is an important determinant access to treatment initiation and adherence in India. Several publicly financed health insurance (PFHI) schemes have been launched India, with for as explicit inclusion the benefit packages (HBPs). Although, financial toxicity widely acknowledged be a potential consequence costly treatment, little known about its prevalence determinants among Indian population. There need determine optimal strategy clinicians care...
Abstract Background Cancer survivors experience a decrement in health-related quality of life (HRQoL) resulting from the disease as well adverse effects therapy. We evaluated HRQoL cancer patients, stratified by primary site, stage, treatment response and associated events, along with its determinants. Methods Data were collected 12,148 sampled seven purposively chosen leading hospitals India, to elicit using EuroQol questionnaire comprising 5-dimensions 5-levels (EQ-5D-5L). Multiple linear...
Background Human papilloma virus (HPV) associated Head and Neck Cancers (HNCs) have generated significant amount of research interest in recent times. Due to high incidence HNCs lack sufficient data on high-risk HPV (hr-HPV) infection from North -East region India, this study was conceived investigate hr-HPV infection, its types association with life style habits such as tobacco, alcohol consumption etc. Methods A total one hundred six primary HNC tumor biopsy specimens were collected. These...
Abstract Background: Evidence linking arsenic in drinking water to digestive tract cancers is limited. We evaluated the association between levels groundwater and gallbladder cancer risk a case–control study (2019–2021) of long-term residents (≥10years) two arsenic-impacted high states India—Assam Bihar. Methods: recruited men women aged 30 69 years from hospitals (73.4% women), with newly diagnosed, biopsy-confirmed (N = 214) unrelated controls frequency-matched for 5-year age, sex, state...
Breast cancer is a heterogeneous disease comprising of distinct biological subtypes with many targeted prognostic biomarkers having therapeutic implications. However, no specific therapy for triple negative breast has been discovered to date and hence further research needed.The aim objectives the present study were examine prevalence (TNBC) in North-East India compare clinicopathological parameters two groups defined by immunohistochemistry (IHC) -"TNBC" "Others".We carried out...
A novel feasible nano capsular approach through co-encapsulation of chloramphenicol and lemon-grass essential oil to combat chronic burn wound infections.
Abstract Background: Head and neck cancers (HNCs) account for 30% of all in India. In north eastern India, tobacco-related are very common because the widespread use tobacco. The paucity any study from this region young head patients has prompted us to take up study. Methodology: A retrospective was conducted at Dr. B Borooah Cancer Institute, Guwahati during January 2015–December 2015. Data regarding tumor site, age, sex, education, habit tobacco (smokeless smoke), betel nut consumption...
Treatment delays are significantly associated with advanced stage, poor response to treatment, increased mortality risk, health outcomes, healthcare expenditures among cancer patients. However, factors these have not yet been robustly evaluated. In order bridge this gap, we determined the delayed time treatment initiation (TTI) patients in India, ascertained its determinants, and assessed trends of TTI. We analysed data collected from 6695 seeking outpatient/daycare recruited at purposively...
The association of TP53 codon 72 polymorphism with cancer susceptibility remains uncertain and varies ethnicity. Northeast India represents a geographically, culturally, ethnically isolated population. area reports high rate tobacco usage in variety ways consumption, compared the rest Indian A total 411 patients (161 lung, 134 gastric, 116 oral) 282 normal controls from ethnic population were analyzed for p53 by polymerase chain reaction–restriction fragment length polymorphism. No...
Abstract Aim: To evaluate carcinoma of the cervix using magnetic resonance imaging (MRI), correlate with clinical approach International Federation Gynecology and Obstetrics (FIGO) staging system to study impact MRI findings on patient management. Method Material: Pathologically confirmed, 75 cases referred our institute from April 2007 March 2008 were prospectively studied. Clinical FIGO stage was assigned each by gynaecologists blinded findings. (based TNM) allotted radiologists...
Esophageal cancer is a major global health burden with strong host-environment interaction component and epigenomics underpinnings that remain to be elucidated further. Certain populations such as the Northeast Indians suffer at disproportionately higher rate from this devastating disease. Promoter methylation correlated transcriptional silencing of various genes in esophageal cancer. Very few studies on genome-wide for exist yet, no one has carried out an integromics analysis gene...
The primary output of hospital-based cancer registries is data on stage and treatment-based survival that can be used to evaluate patient care, but because there are many challenges in obtaining follow-up details, a separate study patterns care for patients at selected sites was initiated under the National Cancer Registry Programme India. This article presents results cervical cancer.A standardized information form record information, were entered into central repository-the Centre Disease...
BACKGROUND: Acute leukemia is a heterogenous disease having diverse phenotypes. Immunophenotyping by flowcytometry essential for diagnosis of myeloid and lymphoid subtypes. Aberrant phenotype incidence controversial dissimilar results have been reported different groups. OBJECTIVES: P urpose the study was to determine aberrant phenotypes in North East Indian patients with acute leukemia. METHODS: We analysed total 100 cases (AML = 36, ALL 61, MPAL 3) multiparametric flow cytometry using an...
An increase in the expression of estrogen receptors (ER) and expanded population ER-positive cells are two common phenotypes breast cancer. Detection aberrantly expressed ERα cancer is carried out using ERα-antibodies radiolabelled ligands to make decisions about treatment targeted therapy. Capitalizing on beneficial advantages aptamer over conventional antibody or ligand, we have identified a DNA that selectively binds facilitates detection human tissue sections. The high throughput...
PURPOSE Tyrosine kinase inhibitors such as sunitinib and pazopanib are the mainstay of treatment metastatic renal cell carcinoma (mRCC) in India. However, pembrolizumab nivolumab have shown significant improvement median progression-free survival overall among patients with mRCC. In this study, we aimed to determine cost-effectiveness first-line options for mRCC METHODS A Markov state-transition model was used measure lifetime costs health outcomes associated sunitinib, pazopanib,...
Introduction The rising economic burden of cancer on healthcare system and patients in India has led to the increased demand for evidence order inform policy decisions such as drug price regulation, setting reimbursement package rates under publicly financed health insurance schemes prioritising available resources maximise value investments health. Economic evaluations are an integral component this important evidence. Lack existing costs health-related quality life (HRQOL) makes conducting...
Background: Persistent infection of one or more about 15 high-risk human papillomaviruses (HR-HPVs), most commonly HPV types 16/18, has a significant role in cervical cancer initiation and progression. There are limited data available from north-east India prevalence though this region high incidence rates cancer. The aim study was to investigate the genotypes prevalent patients India. Materials Methods: We analyzed 107 patient samples. Nested multiplex PCR assays were employed for detection...