A5039589193- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- COVID-19 Clinical Research Studies
- HIV/AIDS drug development and treatment
- Intensive Care Unit Cognitive Disorders
- Healthcare Quality and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- SARS-CoV-2 and COVID-19 Research
- Pharmacovigilance and Adverse Drug Reactions
- CAR-T cell therapy research
- Long-Term Effects of COVID-19
- Healthcare during COVID-19 Pandemic
- HIV-related health complications and treatments
- Medication Adherence and Compliance
- Endometriosis Research and Treatment
- Biosimilars and Bioanalytical Methods
- Healthcare Regulation
- Drug-Induced Adverse Reactions
- Delphi Technique in Research
- Global Cancer Incidence and Screening
- Potassium and Related Disorders
- Retinal and Optic Conditions
- Health Systems, Economic Evaluations, Quality of Life
Hospital de Egas Moniz
2010-2025
Centro Hospitalar de Lisboa Ocidental
2018-2025
University of Lisbon
2021-2023
Since the outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), pressure to minimise its impact on public health has led implementation different therapeutic strategies, efficacy which for treatment coronavirus disease 2019 (COVID-19) was unknown at time. Remdesivir (REM) granted first conditional marketing authorisation in EU June 2020. The European Medicines Agency (EMA) and local authorities all across have since strongly recommended pharmacovigilance activities aimed...
Background Although clinical pharmacy is a crucial part of hospital pharmacist's day-to-day activity, its performance not usually subject to holistic assessment. Objective To define set relevant and measurable support activities key indicators (cpKPI saKPI, respectively). Setting Portuguese Hospital Pharmacies. Method After comprehensive literature review focusing on the metrics already in use other countries, several meetings with directors pharmacies were conducted obtain their...
Coronavirus disease 2019 (COVID-19) is a pandemic infection caused by the newly discovered severe acute respiratory syndrome coronavirus 2. Remdesivir (RDV) and corticosteroids are used mainly in COVID-19 patients with failure. The main objective of study was to assess effectiveness remdesivir without treatment patients. We conducted prospective observational study, including adult consecutively hospitalized confirmed Patients were divided according strategy: RDV alone versus...
Introduction Low‐level viraemia (LLV) is observed in some patients with HIV‐1 infection on stable antiretroviral therapy (ART). The significance of these findings remains controversial as it conflicts traditional optimal clinic outcome. This study aims to evaluate the effect LLV establishment virological failure (VF) and immune deterioration. Methods Retrospective observational a cohort infected an Infectious Diseases Clinic, who presented viral load 20 200 cp/mL, during year 2012. Patients...
Purpose: Riluzole is indicated to prolong life or delay the institution of mechanical ventilation in patients with amyotrophic lateral sclerosis (ALS). Clinical studies have shown that this drug prolongs survival, defined as living who are not intubated for and without tracheotomy. The purpose study characterize riluzole’s use well user population order contribute a rational safe use. Patients methods: Descriptive, observational, retrospective describing characterizing riluzole ALS between...
The COVID-19 pandemic set a challenging scenario for the entire health system and society in general, imposing on hospital pharmacists need to plan organize their staff response challenges posed by COVID-19.In protect teams they restructured service, organizing themselves order not compromise assistance activity and, simultaneously, provide an effective new reality, disregarding technologies review monitoring as well active pharmacovigilance of drugs used treat COVID-19. They created...
Introduction: In late 2014, Portugal implemented a national program for the treatment of patients with chronic hepatitis C directacting antiviral agents. This has made one first European countries to implement structured measure eliminate this serious public health problem. The aim study was assess effectiveness direct-acting therapy in virus infection.Material and Methods: A retrospective observational conducted at Centro Hospitalar de Lisboa Ocidental on online platform from December 2014...
<h3>Background and Importance</h3> Medication errors remain the most common preventable cause of <b>adverse</b> events in drug therapy with further scope for reducing patient harm associated economic burden. <h3>Aim Objectives</h3> This study explores ways improving medication safety clinical practice by evaluating related problems type harm. <h3>Methods</h3> were identified from reports adverse EudraVigilance database classified according to underlying (DRPs) which may be mitigated through...
Despite the increasing optimization of combined antiretroviral therapy (cART) regimens in last decades, a significant percentage patients still do not achieve viral replication control. We present retrospective analysis focusing on human immunodeficiency virus (HIV)‐infected population cART, followed at our ambulatory care clinic between 1st January and 31st December 2011, order to identify causes virological failure. From 1895 we included 1854 study. Ten percent (187) had detectable HIV RNA...
<h3>Background</h3> Hospital settings are of great value in collecting pharmacovigilance data. Introduction innovative drugs hospital raises safety concerns, but allows the study these drugs' profile real life. Pharmacists may play an important role activities. <h3>Purpose</h3> To assess adverse drug reactions (ADRs) 3 recently marketed drugs, introduced a central hospital. <h3>Material and methods</h3> As part our active programme, prospective, observational was carried out on patients...
<h3>Background</h3> Iron deficiency anaemia (IDA) is a common condition. The pharmacy intravenous iron protocol (100 mg/5 ml sucrose vials) includes assessment of patient analytical data, dose calculation, schedule and information about administration intended to prevent adverse reactions. <h3>Purpose</h3> To assess the use in hospitalised patients being treated by protocol. <h3>Materials Methods</h3> An eight-month retrospective, observational study (January August 2012). Hospitalized with...
7-11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK Since the use of more tolerable and less toxic combined antiretroviral (ARV) therapy, most drug-naïve patients achieve viral suppression immunologic recovery, with AIDS related events. Nevertheless, drug switches are still frequent both as a mean adherence toxicity management response to virologic or failure. The aim study was analyse number, timing cause modifications first ARV regimen order...
The current concept of hospital pharmacy (HP) focuses on the existence two major areas: logistics and clinical. Thus, HP is not only product or patient oriented but a combination both. Trends in development use medications are key factors that will shape our profession coming years; others related to national global economy status healthcare reform. These demand pharmacists continue move towards team leadership drug therapy management, aiming for …
7‐11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK
Certification of management systems is the attestation by a Body, based on decision analysis, which confirms that specified requirements and their conformity have been demonstrated. It therefore aims to show publicly in writing particular product, process or service conforms requirements. The provision health services has two quality components: operational component, itself; one perception, how customers perceive type offered providers feel about what they are providing. Management direct...
<h3>Background and importance</h3> The COVID-19 vaccines have shown excellent safety efficacy profiles. Healthcare workers (HCW), a priority group for vaccination in Portugal, were probably the first to receive mixed COVID-19. A previous study reported more adverse events (AE) after using two different adults aged 50 years older. To our knowledge, there are no data younger individuals. <h3>Aim objectives</h3> identify compare self-reported AE second dose of Pfizer or AstraZeneca HCW who...