Incidence of visual impairment (VI) and dyslipidemia is increasing with aging. Although good medication adherence (MA) a crucial factor in achieving therapeutic goals for dyslipidemia, there paucity studies measuring MA the visually impaired dyslipidemia. We investigated whether patients VI had worse to drugs than non-disabled people determined factors affecting among VI. Data on were extracted 2017 from sample cohort database National Health Insurance Service. was measured two years based...

Korean American youth experience immigration-related parent-child challenges including language barriers, conflicts, and generational cultural divides. Using grounded theory methods, this article examines the ways in which 18 college-enrolled emerging adults retrospectively made sense out of their experiences immigrant family hardships. Of those who narrated childhood hardship, over half positive change they reinterpreted relationship to parents redeemed either through own maturation or...

Fibroblast growth factor (FGF) 9 is secreted by both mesothelial and epithelial cells, plays important roles in organ development wound healing via WNT/β-catenin signaling. The aim of this study was to evaluate FGF9 expression FGF-WNT/β-catenin signaling during the skin. We investigated after laser ablation mouse skin adult human skin, as well cultured normal epidermal keratinocytes (NHEKs) upon stimulation with recombinant (rh) rh-transforming (TGF)-β1. Our results showed that leads marked...

Aims Haemophilia A patients with factor VIII inhibitors (HAPI) experience frequent spontaneous bleeding, approximately once a week, and require expensive bypassing agent (BPA) treatments to control bleeding over their lifetime. According the HAVEN 1 trial, weekly emicizumab (Hemlibra®) prophylaxis injection reduces annualized rates (ABR) by 87% compared BPA on-demand treatment (BPA-OD) administered at time of bleeding. Our study aimed assess cost-effectiveness in HAPI Korea. Methods Using...

Background and Purpose Guillain-Barré syndrome (GBS) is rare, but its symptoms are severe they occasionally lead to long-term disability.Country-specific epidemiological evidence useful for detecting potential problems at the population level.This study investigated economic characteristics of GBS in South Korea.Methods The Korean National Health Insurance Service claims data from 2010 2016 were used identify incident cases as newly hospitalized patients with a primary diagnosis (the 10th...

This research explored Korean American (KA) young adults’ experiences related to their sense of indebtedness toward parents and perceptions how affected behavior parents. Semistructured interviews were conducted with 25 KA adults from immigrant families. Most respondents narrated parents, verbally acknowledging appreciation for parents’ hardship sacrifice; however, they differed in much internalized indebtedness, varying level personalization perception salience indebtedness. Similarly,...

This research examined the construct “sense of indebtedness toward parents” (SIP) as a concept that helps explain positive change in Korean American (KA) emerging adults’ views their parents despite experiencing high level parent-adolescent challenges. Semi-structured interviews were conducted with 25 KA adults. Most described SIP, defined “a person’s recognition his or her immigrant parents’ child-centered immigration aspirations and sacrifice for sake children.” Findings showed formation...

Background: To assess the cost-effectiveness of drug therapy to prevent osteoporotic fractures in postmenopausal women with osteopenia Korea.Methods: A Markov cohort simulation was conducted for lifetime a hypothetical and without prior fractures.They were assumed receive calcium/vitamin D supplements only or (i.e., raloxifene risedronate) along 5 years.The model includes fracture-specific non-fracture specific health states (i.e.breast cancer venous thromboembolism), all-cause...

Although corporate social responsibility (CSR) activities are common in the pharmaceutical industry, there is little empirical evidence on consumer responses to CSR practices. We investigated public awareness, preferences, and expectations regarding contribution of industry's activities, identified factors associated with such activities. conducted an online survey 1,298 respondents comprising two groups: healthy individuals (546) patients (752). Most (78%) expressed interest undertaken by...

The number of people with HIV/AIDS has consistently increased in Korea since the first case infection was reported 1985. depressive symptoms patients may lead to medication non-adherence. This study sought investigate cross-sectional and longitudinal association between depression antiretroviral treatment adherence Korean population.We included participants cohort 2009 2017. All information collected at enrollment every annual visit, including sociodemographic characteristics, health-related...

Rotavirus is a leading cause of severe gastroenteritis among children younger than 5 years in South Korea. Two rotavirus vaccines (RVs), pentavalent human-bovine reassortant vaccine (Rotateq®; RV5) and attenuated human strain originated monovalent (Rotarix®; RV1), have been available for voluntary vaccination using out-of-pocket payment since 2007 2008, respectively. Yet, RVs are not included the National Immunization Program (NIP), partly because low associated mortality rate. We assessed...

Objective To investigate and compare the attitudes of operating room nurses doctors regarding patient safety, performance surgical time-out recognition count error. Methods This cross-sectional study recruited nurses, surgeons anaesthesiologists between 1 August 2015 5 February 2016. A Safety Attitude Questionnaire was used to analyse three elements in both groups staff (nurses doctors). Results The analysed questionnaires from 171 participants; 95 (55.6%) 76 (44.4%). Differences exist...

This article presents new horizons for research on youth development by focusing the challenges face in learning teamwork and coming to terms with diversity. These are both essential competencies navigating “real world” of 21st century. We examine how experience these within programs; also they present second-order practitioners. The underlying message this is that it researchers see programs from point view people them. Researchers have learned quite a bit what can be arm’s length: make...

Abstract As the importance of utilizing real‐world data (RWD)/real‐world evidence (RWE) for supporting regulatory scientific decision‐making continues to grow, experiences and inputs from experts become crucial developing a systematic practice‐oriented plan use fit‐for‐purpose RWD/RWE. This study aimed survey relevant government agencies, industries, academia identify prerequisites drug life cycle in Korea. The questionnaire comprised following: (A) definition categories RWD/RWE, (B)...

The prevalence of heart failure (HF) and its economic burden are increasing with age the South Korean population. This study aimed to assess impact HF from societal perspective.A prevalence-based, incremental cost-of-patient was performed estimate cost ratio between patients those without based on claims database national health insurance in Korea. We defined adult as aged ≥19 years who had at least one claim record a primary or secondary diagnosis HF. Age- gender-matched controls were using...

Abstract Background The concurrent use of anticholinergics and acetylcholinesterase inhibitors (ACHEIs) in Parkinson’s disease (PD) patients with dementia should be avoided because the opposing pharmacological actions both drugs reduce treatment efficacy. We aimed to investigate prevalence these two types Korean patients. Methods In 2017 Health Insurance Review Assessment Service–National Aged Patient Sample data, comprising insurance claims records for a 10% random sample aged ≥ 65 years...

Hospitalization rates for ambulatory care sensitive conditions (ACSCs) can indicate the accessibility of a community's primary care. We examined regional variation in ACSC hospitalization and identified associated factors. 232 districts 2013 ranged from 4.08 to 101.53 per 1000 adults. Spatial analysis showed that none 24 highest rate were located near Seoul, whereas 80% 45 lowest were, suggesting health inequality between people living Seoul other areas. Regression significantly higher with...

Objective This study examined the nature and extent of parental participation in process adolescents joining an organized program identify factors underlying variations overarching patterns participation. Background Adolescents become increasingly interested making their own choices decisions. Thus, families must balance goals adolescents' desire for autonomy social activities. Method Interviews were conducted with 62 adolescent participants 52 parents. Data analyses followed inductive...

In this paper, we present a low-power 10 Bit Successive Approximation Register (SAR) Analog-to-Digital Converter (ADC) which is suitable for low power mixed signal applications especially IoT devices. We have used Class-AB type amplifier in Reference generator of SAR ADC to reduce current consumption and satisfy the linearity property better performance ADC. The proposed circuit uses CMOS 0.18 μm process technology supply voltage 5 V. ENOB 9.623 SNDR 58.688 dB with 0.44 mA.