Simran Arjani

ORCID: 0000-0003-3269-648X
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About
Contact & Profiles
Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • Pancreatitis Pathology and Treatment
  • Cancer Risks and Factors
  • Diverticular Disease and Complications
  • Adrenal and Paraganglionic Tumors
  • Cancer Immunotherapy and Biomarkers
  • Diversity and Career in Medicine
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Radiation Dose and Imaging
  • Renal cell carcinoma treatment
  • Adrenal Hormones and Disorders
  • Thyroid Cancer Diagnosis and Treatment
  • Hormonal Regulation and Hypertension
  • Cancer Diagnosis and Treatment
  • Colorectal Cancer Screening and Detection
  • Medical Education and Admissions
  • Economic and Financial Impacts of Cancer
  • Healthcare Policy and Management
  • Gastrointestinal Tumor Research and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Multiple and Secondary Primary Cancers
  • Urologic and reproductive health conditions
  • IgG4-Related and Inflammatory Diseases
  • Health Systems, Economic Evaluations, Quality of Life

Montefiore Medical Center
2022-2025

Albert Einstein College of Medicine
2024-2025

Rutgers New Jersey Medical School
2019-2024

The Bronx Defenders
2024

Rutgers, The State University of New Jersey
2019-2024

National Cancer Institute
2021-2022

National Institutes of Health
2021-2022

The Ohio State University Wexner Medical Center
2022

American Association of Neurological Surgeons
2021-2022

Harvard University
2019

Abstract Pancreatic cancer (PC) is highly fatal, and its incidence increasing in the United States. Population‐based registry studies suggest associations between a few autoimmune conditions PC risk, albeit based on relatively small number of cases. We conducted population‐based, nested case‐control study to examine risk within Surveillance, Epidemiology, End Results Program (SEER)‐Medicare population. Incident primary malignant cases (n = 80 074) were adults ≥66 years diagnosed 1992 2015....

10.1002/ijc.34235 article EN International Journal of Cancer 2022-08-01

Body mass index (BMI) during adulthood has been associated with pancreatic ductal adenocarcinoma (PDAC), however, patterns of body size across the adult life course have not studied extensively. We comprehensively evaluated association between adiposity and PDAC.We conducted a prospective analysis 269 480 (162 735 males, 106 745 females) National Institutes Health-AARP Diet Health Study participants, aged 50-71 years (1995-1996) who self-reported height weight history. Participants were...

10.1093/jncics/pkac066 article EN cc-by-nc-nd JNCI Cancer Spectrum 2022-10-18

Lifestyle medicine has the power to reverse growing burden of chronic disease that now plagues our health care system. The World Health Organization, Centers for Disease Control and Prevention, American College Medicine have all independently recognized need community-centered lifestyle education as a means empowering individuals take charge their own health. Students in undergraduate, medical, allied schools may serve mediators these conversations. With guidance from faculty mentors,...

10.1177/1559827619836970 article EN American Journal of Lifestyle Medicine 2019-03-24

Objective To perform a comparative analysis of postthyroidectomy radioactive iodine ablation dosing with or without the implementation diagnostic whole‐body scan in patients well‐differentiated thyroid cancer. Study Design Decision model. Setting Hospital ambulatory center. Methods A decision tree model was created to determine cost‐effectiveness dosed scans versus empiric differentiated cancer undergoing ablation. The populated values from published literature. Costs were represented by...

10.1177/0194599820966982 article EN Otolaryngology 2020-10-20

Across the nation, patients with locally advanced gastric cancer (LAGC) are managed modalities including upfront surgery (US) and perioperative chemotherapy (PCT). Preoperative therapies have demonstrated survival benefits over US thus long-term outcomes expected to vary between options. However, as these 2 continue be regularly employed, we sought perform a decision analysis comparing costs quality-of-life associated treatment of LAGC identify most cost-effective option. We designed tree...

10.1177/00031348241227180 article EN The American Surgeon 2024-01-15

Pancreatic adenocarcinoma portends poor survival despite high treatment cost. Staging is commonly performed with computed tomography (CT), which may fail to capture small metastases. Laparoscopy and peritoneal cytology after initial CT improve accuracy of staging. This study analyzed cost-effectiveness alone diagnostic laparoscopy subsequent neoadjuvant therapy in pancreatic adenocarcinoma. A decision tree was constructed comparing for Branch-point probabilities, survival, utility weights...

10.1016/j.cpsurg.2024.101442 article EN cc-by Current Problems in Surgery 2024-01-21

Secondary prostate cancer typically occurs from direct seeding of a renal or bladder tumor. Metastasis via hematogenous spread is exceedingly rare and identified incidentally at autopsy. This report describes 72-year-old male with lung adenocarcinoma initially staged as Stage IA2 who developed oligometastatic disease the prostate. He was treated radiation therapy found to have hypermetabolic focus in gland during surveillance PET/CT imaging 6 months following treatment. Subsequent biopsy...

10.3389/fonc.2024.1394168 article EN cc-by Frontiers in Oncology 2024-05-22

Pancreatic cancer (PC) has an overall 5-year survival rate of 10%. The use neoadjuvant chemoradiation is debated in resectable disease. purpose this study to evaluate the cost-effectiveness followed by pancreaticoduodenectomy (NACRT) versus upfront and adjuvant chemotherapy (USR) PC.A decision tree model was used estimate NACRT USR. Values from published literature populate tree: costs Medicare (FY2021) reimbursements, morbidity data for quality-adjusted life-years (QALYs). Patients with...

10.1200/op.22.00536 article EN JCO Oncology Practice 2022-12-22

e16065 Background: Across the nation, patients with locally advanced gastric cancer (LAGC) are managed modalities including upfront surgery (US), neoadjuvant chemoradiation therapy (NCRT), and perioperative chemotherapy (PCT). Treatment themselves associated adverse effects which can lead to difficulty treatment adherence in short-term. As preoperative therapies have demonstrated survival benefits over US, long-term outcomes expected vary, but it is not known if differences impacts...

10.1200/jco.2023.41.16_suppl.e16065 article EN Journal of Clinical Oncology 2023-06-01

Abstract Pancreatic cancer (PC) is highly fatal, and its incidence increasing in the United States. Population-based registry studies suggest associations between a few autoimmune conditions PC risk, albeit based on relatively small number of cases. We hypothesize that are associated with risk PC. conducted population-based, nested case-control study to examine association within Surveillance, Epidemiology, End Results Program (SEER)-Medicare population. Incident primary malignant cases...

10.1158/1538-7445.panca22-b082 article EN Cancer Research 2022-11-15

Introduction: Initial staging of pancreatic ductal adenocarcinoma (PDAC) is performed with computed tomography (CT). Laparoscopy peritoneal cytology at can uncover occult disease undetected by CT. This case series assessed clinical course following laparoscopy in patients PDAC. Methods: single-center study examined non-metastatic PDAC diagnosed from 2017 to 2020. Patients underwent CT and subsequent prior treatment. Demographics, clinicopathologic status, treatment course, survival were...

10.7759/cureus.31883 article EN Cureus 2022-11-25

e16079 Background: The most commonly used treatment options for gastric cancer include complete resection with adequate margins either perioperative chemotherapy (PCT) or adjuvant chemoradiotherapy (CRT). While both strategies have shown superiority over surgical alone, it is not clear which strategy more optimal. Methods: Our decision tree model was built to analyze the survival and costs associated two major management methods: chemoradiation therapy. Costs were obtained from Medicare...

10.1200/jco.2021.39.15_suppl.e16079 article EN Journal of Clinical Oncology 2021-05-20

Abstract Background: Adiposity is associated with pancreatic ductal adenocarcinoma (PDAC), but the effects of weight excess over an adult life course have not been studied extensively. We examined association between trajectories body mass index (BMI) from ages 18 up to 71 years and risk subsequent PDAC. Methods: Our analysis included 270,722 (163,873 men, 106,849 women) NIH-AARP Diet Health Study participants, 50-71y, who successfully completed questionnaires self-reported height at 18, 35,...

10.1158/1538-7445.am2021-853 article EN Cancer Research 2021-07-01
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