A5007748519- Biochemical effects in animals
- Diet and metabolism studies
- Brain Tumor Detection and Classification
- Pharmacological Effects of Natural Compounds
- Image Retrieval and Classification Techniques
- Adipokines, Inflammation, and Metabolic Diseases
- Cholesterol and Lipid Metabolism
- Cardiovascular Function and Risk Factors
- Helicobacter pylori-related gastroenterology studies
- Cancer, Hypoxia, and Metabolism
- COVID-19 diagnosis using AI
- Gastrointestinal motility and disorders
- Curcumin's Biomedical Applications
- Aldose Reductase and Taurine
- Computational Drug Discovery Methods
- Advanced Glycation End Products research
- Inflammatory Bowel Disease
- Medicinal Plants and Neuroprotection
- Alcoholism and Thiamine Deficiency
- Natural product bioactivities and synthesis
- Amino Acid Enzymes and Metabolism
- Traditional Chinese Medicine Studies
- Cardiovascular Disease and Adiposity
- Clinical Nutrition and Gastroenterology
- Phytochemicals and Medicinal Plants
Universidade Estadual de Maringá
2013-2024
The aim of our study was to the pathological mechanisms induced by rheumatoid arthritis (RA) on Enteric Nervous System (ENS).We evaluated effect chronic and its treatment with 50 mg/kg quercetin alone (AQ) combined 17.5 ibuprofen (AIQ) for 60 days neurons, glial cells intestinal wall. Other groups were used: control (C), arthritic (A) treated (AI). After days, jejunum removed processed immunohistochemical techniques. Immunostainings performed HuC/D S100 (myenteric submucosal plexuses), GFAP...
The present study investigated the in vitro and vivo antioxidant potential phytochemical composition of Schinus terebinthifolia, which is widely used folk medicine for various therapeutic purposes. analyses indicated that hydroethanolic extract (HE) had 312.50 ± 0.50 mg GAE/g total phenols. It also presented anti-DPPH• anti-ABTS•+ activity, reduced phosphomolybden metal ions blocked bleaching β-carotene. HE at concentrations 3.0 2.0 μg/mL TRAP values 2.223 0.018 1.894 0.026 μM Trolox,...
This study aimed to analyze the effects of quercetin (100 mg/kg), 1% glutamine and α-tocopherol antioxidants in myocardium rats with streptozotocin-induced diabetes mellitus. Twenty male were subdivided into four groups (n = 5): N (normoglycemic); D (diabetic); NT (normoglycemic treated antioxidants); DT (diabetic antioxidants) for 60 days. Clinical parameters, oxidative stress markers, inflammatory cytokines, myocardial collagen fibers immunoexpression superoxide dismutase 1 (SOD-1),...
This study aimed to investigate the antioxidant and anti-inflammatory properties of quercetin on cellular components Enteric Nervous System in ileum rats with arthritis. Rats were distributed into five groups: control (C), arthritic (AIA), treated ibuprofen (AI), (AQ) both (AIQ). The was processed for immunohistochemical techniques HuC/D, calcitonin gene-related peptide, vasoactive intestinal polypeptide. Measurements histological sections, chemiluminescence assays, total capacity also...
Studies recently accomplished on the Enteric Nervous System have shown that chronic degenerative diseases affect Glial Cells (EGC) and, thus, development of recognition methods able to identify whether or not EGC are affected by these type may be helpful in its diagnoses. In this work, we propose use pattern and machine learning techniques evaluate if a given animal image was obtained from healthy individual one disease. proposed approach, performed classification task with handcrafted...