A5028409250- Neural dynamics and brain function
- Receptor Mechanisms and Signaling
- Circadian rhythm and melatonin
- Neuroendocrine regulation and behavior
- Memory and Neural Mechanisms
- Olfactory and Sensory Function Studies
Université Paris Cité
2024
Institut Pasteur
2024
HUN-REN Institute of Experimental Medicine
2021
Institut de Biologie de l'École Normale Supérieure
2021
Negative bias is an essential characteristic of depressive episodes leading patients to attribute more negative valence environmental cues. This affects all levels information processing including emotional response, attention and memory, the development maintenance symptoms. In this context, pleasant stimuli become less attractive unpleasant ones aversive, yet related neural circuits underlying remain largely unknown. By studying a mice model for depression chronically receiving...
High throughput, temporally controlled, reproducible quantitative behavioral assays are important for understanding the neural mechanisms underlying behavior. Here, we provide a step-by-step training protocol probabilistic Pavlovian conditioning task, where two auditory cues predict outcomes with different contingencies. This allows us to study differential and neuronal correlates of expected surprising outcomes. It has been tested in combination chronic vivo electrophysiological recordings...