L. Ruiz

ORCID: 0000-0003-3298-8132
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About
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Research Areas
  • Systemic Sclerosis and Related Diseases
  • Inflammatory Myopathies and Dermatomyositis
  • Skin Diseases and Diabetes
  • Biosimilars and Bioanalytical Methods
  • Inflammatory Bowel Disease
  • Pharmaceutical studies and practices
  • Dermatological and Skeletal Disorders
  • Research on Leishmaniasis Studies
  • Microscopic Colitis
  • Muscle and Compartmental Disorders
  • Celiac Disease Research and Management
  • Connective Tissue Growth Factor Research
  • Facial Nerve Paralysis Treatment and Research
  • Eosinophilic Esophagitis
  • Heterotopic Ossification and Related Conditions
  • Facial Rejuvenation and Surgery Techniques
  • Clinical Reasoning and Diagnostic Skills
  • Education and Critical Thinking Development
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Innovations in Medical Education
  • Dermatologic Treatments and Research
  • Ear Surgery and Otitis Media
  • HIV-related health complications and treatments
  • Sex and Gender in Healthcare
  • Body Contouring and Surgery

Hospital General Universitario De Valencia
2022-2025

Autonomous University of Chihuahua
2023

Hospital Universitario Miguel Servet
2021

Hospital Universitario Príncipe de Asturias
2015-2020

Center for Rheumatology
2016

Hospital del Niño
2015

ABSTRACT Background Leishmaniasis (LI) is a vector‐borne illness caused by protozoan of the genus Leishmania . Data on features LI in patients with inflammatory bowel disease (IBD) are scarce. Aim To describe characteristics IBD who present leishmaniasis, infection outcomes and risk factors associated developing visceral leishmaniasis (VL). Methods An observational retrospective study performed 26 hospitals Spain, including all adult developed from 2012 to 2022. Results A total 73 were...

10.1002/ueg2.12740 article EN cc-by-nc-nd United European Gastroenterology Journal 2025-01-08

Abstract Background Leishmaniasis (LI) is a vector-borne illness caused by protozoan of the genus Leishmania. Data on features LI in patients with inflammatory bowel disease (IBD) are scarce. Aim To describe characteristics IBD who present LI, infection outcomes and risk factors associated developing visceral leishmaniasis (VL). Methods Observational, retrospective study performed 26 hospitals Spain, including all adult developed from 2012 to 2022. Results A total 73 were included. The...

10.1093/ecco-jcc/jjae190.1190 article EN Journal of Crohn s and Colitis 2025-01-01

Abstract Background Biosimilar infliximab (CT-P13) has been available for subcutaneous (SC IFX) administration since march 2021. It shown to be equivalent its every-8-week-intravenous formula (IV IFX), however, we do not have long term efficacy and safety data. Our aim was evaluate medication persistence, two years after switching from IFX IV SC Methods Multicentre, descriptive, observational study, with prospective data collection, of Crohn’s Disease (CD) or Ulcerative Colitis (UC) patients...

10.1093/ecco-jcc/jjad212.0787 article EN Journal of Crohn s and Colitis 2024-01-01

Abstract Background Evidence suggests that subcutaneous formulation of biosimilar infliximab (CT-P13) (SC-IFX) is capable to maintain clinical remission safely and increase drug levels with a good acceptance in patients Crohn’s disease (CD) ulcerative colitis (UC) patients. The aims this study were evaluate which are the adequate concentration thresholds remission, factors involved long-term outcomes. Methods Multicentre, descriptive, observational including CD UC who going be switched from...

10.1093/ecco-jcc/jjad212.0646 article EN Journal of Crohn s and Colitis 2024-01-01

La deformidad de orejas en pantalla o prominauris es una las deformidades congénitas más frecuentes la región cabeza y cuello representa principal alteración del pabellón auricular, lo que afecta aproximadamente al 5 % población mundial. Las principales alteraciones causan esta son falta formación antihélix concha prominente. técnicas quirúrgicas otoplastia se pueden agrupar dos grandes grupos: basadas el uso suturas consisten corte cartílago auricular. En actualidad existen gran cantidad...

10.37076/acorl.v52i1.748 article ES ACTA DE OTORRINOLARINGOLOGÍA & CIRUGÍA DE CABEZA Y CUELLO 2024-04-26

Background: Primary fibromyalgia syndrome is a prevalent rheumatic condition characterized by widespread pain and whose etiopathogenesis not well understood. Fibromyalgia can also be secondary to other diseases like Sjogren’s syndrome; however, its relation this disease unknown. It has been suggested that the immune system involved in their pathogenesis. The role of activation stages cytokines profiles CD4+T lymphocytes or Sjogren´s are completely unclear could play key pathophysiology these...

10.1136/annrheumdis-2020-eular.5524 article EN Annals of the Rheumatic Diseases 2020-06-01

Introducción: El pensamiento crítico se define como la formación de un juicio con propósito específico cuyo resultado puede explicarse según evidencia. Un alumno posgrado medicina debe explorar los componentes del para lograr plantear, evaluar y comunicar problemas complejos. Objetivo: Determinar si existe alguna diferencia en autopercepción médicos residentes diferentes especialidades médicas distintos grados académicos.Método: Se trata estudio transversal, observacional analítico realizado...

10.22201/facmed.20075057e.2020.35.20225 article ES Investigación en Educación Médica 2020-07-07

<h3>Background</h3> The presence of Raynaud9s phenomenon involves the screening connective pathologies. Because today capillaroscopy has become important as diagnostic criteria for scleroderma, within protocol evaluation patients with Raynaud it would be appropriate to hold at least one capillaroscopy, hence interest this study. <h3>Objectives</h3> Descriptive study capillaroscopic findings in primary suspected without other clinical data <h3>Methods</h3> Capillaroscopic reports were...

10.1136/annrheumdis-2015-eular.5602 article EN Annals of the Rheumatic Diseases 2015-06-01

<h3>Background</h3> Clinical manifestations and prognosis of idiopathic inflammatory myopathies (IIM) are extremely heterogeneous which, combined with its low prevalence, makes difficult the study disease in absence multicenter studies. <h3>Objectives</h3> To analyze clinical characteristics mortality a cohort patients diagnosed IIM rheumatology units from several hospitals Madrid. <h3>Methods</h3> A retrospective longitudinal descriptive REMICAM myositis group was performed. All according...

10.1136/annrheumdis-2015-eular.5459 article EN Annals of the Rheumatic Diseases 2015-06-01

<h3>Background</h3> Nailfold capillaroscopy is a simple, safe, low cost and non-invasive screenig test together with the study of autoantibodies, useful in diagnosis systemic sclerosis (SSc). It demonstrates certain specific patterns which are characterized by presence dilated capillaries, haemorrhages avascular areas. Other autoimmune rheumatic diseases (ARD) do not have pattern, but alterations morphology capillaries such as increased tortuosity been described SLE. In other mixed...

10.1136/annrheumdis-2015-eular.5631 article EN Annals of the Rheumatic Diseases 2015-06-01

<h3>Background</h3> Systemic Sclerosis (SSc) is a multisystem autoimmune disease characterized by fibrosis of the skin and internal organs vascular damage. The diagnosis usually made in late stages, when irreversible damage has already occurred. Recently, we have established new criteria to detect early cases disease. Performing capillaroscopy its findings are crucial SSc or "prescleroderma" there may be changes seen capillaries patients without manifestations. <h3>Objectives</h3> To analyze...

10.1136/annrheumdis-2015-eular.5568 article EN Annals of the Rheumatic Diseases 2015-06-01

<h3>Background</h3> Some studies suggest that clinical subgroups of idiopathic inflammatory myopathies (IIM) and several myositis-specific antibodies (MSAs) could influence the prognosis IIM with interstitial lung disease (ILD). <h3>Objectives</h3> To investigate value different MSAs in a cohort patients -associated ILD. <h3>Methods</h3> We analyzed IIM-associated ILD included multicenter registry REMICAM (1980–2014). compared between a) IIM: dermatomyositis (DM) vs. polymiosytis (PM)...

10.1136/annrheumdis-2016-eular.2136 article EN Annals of the Rheumatic Diseases 2016-06-01

<h3>Background</h3> Cardiovascular complications are a common cause of morbidity in inflammatory arthritis and connective tissue diseases like several studies have shown. <h3>Objectives</h3> Detection cardiovascular risk factors endothelial dysfunction patients diagnosed with Systemic Sclerosis (SSc) Mixed Connective Tissue Disease (MCTD). Creation longitudinal cohort patients. <h3>Methods</h3> Studies been collected from April 2012 to December 2015. The data collection protocol included...

10.1136/annrheumdis-2016-eular.6125 article EN Annals of the Rheumatic Diseases 2016-06-01

<h3>Background</h3> Clinical manifestations, evolution and prognosis of idiopathic inflammatory myopathies (IIM) are very heterogeneous which, together with its low prevalence, limits the study disease. <h3>Objectives</h3> To analyze clinical characteristics patients diagnosed IIM in a multicenter study. <h3>Methods</h3> A retrospective descriptive from REMICAM<sup>1</sup> myositis group was performed. All were according to Bohan Peter<sup>2</sup> criteria, followed up sometime between...

10.1136/annrheumdis-2016-eular.2577 article EN Annals of the Rheumatic Diseases 2016-06-01

<h3>Background</h3> Classically the prognosis of idiopathic inflammatory myopathies (IIM) has improved in recent decades, but can still be poor certain subgroups or presence some clinical factors. <h3>Objectives</h3> To analyze survival, causes death and factors a cohort patients diagnosed with IIM. <h3>Methods</h3> A multicenter retrospective study from REMICAM<sup>1</sup> myositis group was performed. All were IIM according to Bohan Peter<sup>2</sup> criteria classified into 5 different...

10.1136/annrheumdis-2016-eular.2276 article EN Annals of the Rheumatic Diseases 2016-06-01

Hairline reduction surgery, also known as aesthetic forehead reduction, is a surgical procedure that aims to reduce the upper facial third and improve harmony. This article describes anatomy of hairline advancement surgery technique used by author. The study included 21 patients from 2019 2023, length was on average 22.48 ± 2.64 mm. most common complaint hypoesthesia scalp, present in 100% patients, resolving all cases 2 months after surgery. Forehead among procedures provide more...

10.1055/a-2235-7312 article EN Facial Plastic Surgery 2023-12-27

<h3>Background</h3> Idiopathic inflammatory myopathies (IIM) comprise a heterogeneous group of autoimmune conditions. Joint involvement can be considered to part the IIM systemic manifestations, together with possible gastrointestinal, cardiovascular and/ or pulmonary involvement. Although articular in has been described as variable and non-specific chronic course it might an early symptom dermatomiositis up 30% cases those patients overlap syndromes. <h3>Objectives</h3> To evaluate identify...

10.1136/annrheumdis-2017-eular.7051 article EN Annals of the Rheumatic Diseases 2017-06-01

<h3>Background</h3> Interstitial lung disease (ILD) in idiopathic inflammatory myopathies (IIM) may appear at any time evolution and is associated with a worse prognosis. <h3>Objectives</h3> To investigate sociodemographics data clinical characteristics of patients IIM ILD from the REMICAM registry. <h3>Methods</h3> A multicenter retrospective study (1980–2014) was performed. Patients were classified as polymiosytis (PM), dermatomyositis (DM), anti-synthetase antibodies (AB) overlap...

10.1136/annrheumdis-2017-eular.3268 article EN Annals of the Rheumatic Diseases 2017-06-01

<h3>Background</h3> Inflammatory myopathies (IIM) are a heterogeneous group of autoimmune rheumatic diseases characterized by muscle inflammation and progressive weakness. They include any kind primary inflammatory disease that is not otherwise better explained metabolic, toxic, infectious, neurologic or inherited causes. The presence autoantibodies (AA) in IIM variable they can recognize nuclear cytoplasmic cellular components. <h3>Objectives</h3> To evaluate the AA profile patients...

10.1136/annrheumdis-2017-eular.7050 article EN Annals of the Rheumatic Diseases 2017-06-01

Abstract Background Aims: 1) to compare persistence on adalimumab treatment over time in inflammatory bowel disease (IBD) patients who maintained reference [non-switch cohort (NC)] vs. those switched from biosimilar [switch (SC)]; 2) loss of effectiveness the NC SC; 3) identify factors associated with discontinuation therapy; 4) relapse both cohorts; and 5) evaluate safety strategies. Methods Retrospective, observational, multicentre study. Patients under were clinical remission at standard...

10.1093/ecco-jcc/jjab232.646 article EN Journal of Crohn s and Colitis 2022-01-01
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