- Transcranial Magnetic Stimulation Studies
- Electroconvulsive Therapy Studies
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Neuroscience and Neural Engineering
- Treatment of Major Depression
- Attention Deficit Hyperactivity Disorder
- Neurological disorders and treatments
- Tryptophan and brain disorders
- Obsessive-Compulsive Spectrum Disorders
- Vestibular and auditory disorders
- Muscle activation and electromyography studies
- Pain Management and Treatment
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Motor Control and Adaptation
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Cognitive Functions and Memory
- Migraine and Headache Studies
- Cardiac Valve Diseases and Treatments
- Hospital Admissions and Outcomes
- Genetic Neurodegenerative Diseases
- Thyroid and Parathyroid Surgery
- Neuroscience and Neuropharmacology Research
UNSW Sydney
2015-2025
Black Dog Institute
2013-2025
The George Institute for Global Health
2023-2025
St George Hospital
2012-2016
Prince of Wales Hospital
2013-2015
Committee on Publication Ethics
2015
Neuroscience Research Australia
2015
South Eastern Sydney Local Health District
2012-2013
Singapore General Hospital
2013
National Health and Medical Research Council
2013
Background Preliminary evidence suggests transcranial direct current stimulation (tDCS) has antidepressant efficacy. Aims To further investigate the efficacy of tDCS in a double-blind, sham-controlled trial (registered at www.clinicaltrials.gov : NCT00763230). Method Sixty-four participants with depression received active or sham anodal to left prefrontal cortex (2 mA, 15 sessions over 3 weeks), followed by 3-week open-label treatment phase. Mood and neuropsychological effects were assessed....
Two recent sham-controlled studies found that transcranial direct current stimulation (tDCS) was an effective treatment for depression. As tDCS is painless, relatively safe and inexpensive, its efficacy in treating depression warrants further investigation. This double-blind, randomized study tested at the same parameters as a previous positive (1 mA strength, five sessions, active or sham, given on alternate days) 40 depressed participants. Anodal centred over left dorsolateral prefrontal...
Abstract Computer-administered cognitive training (CT) tasks are a common component of remediation treatments. There is growing evidence that transcranial direct current stimulation (tDCS), when given during tasks, improves performance. This randomized, controlled trial explored the potential synergistic effects CT combined with tDCS in healthy participants. Altogether, 60 participants were randomized to receive either active or sham administered on an adaptive task (dual n-back task),...
The effect of transcranial direct current stimulation (tDCS) is cumulative. Treatment protocols typically require multiple consecutive sessions spanning weeks or months. However, traveling to clinic for a tDCS session can present an obstacle subjects and their caregivers. With modified devices headgear, treatment be administered remotely under clinical supervision, potentially enhancing recruitment, throughput, convenience. Here we propose standards trials utilizing remotely-supervised with...
A sample of 160 hospitalized, acute myocardial infarction patients and 138 individuals who died prior to hospitalization from coronary heart disease were studied determine the incidence duration prodromal symptoms action taken cope with symptoms. Seventy percent in-hospital subsample (IHS) 64% out-hospital (OHS) reported prodromata. The OHS a significantly longer median than IHS (29 versus 10.5 days). Sixty-seven new or accelerated anginal as most frequently occurring symptom, in contrast...
Background Prior trials suggest that intravenous racemic ketamine is a highly effective for treatment-resistant depression (TRD), but phase 3 of are needed. Aims To assess the acute efficacy and safety 4-week course subcutaneous in participants with TRD. Trial registration: ACTRN12616001096448 at www.anzctr.org.au . Method This 3, double-blind, randomised, active-controlled multicentre trial was conducted seven mood disorders centres Australia New Zealand. Participants received twice-weekly...
Objective Prior studies of quality life among cardiac patients have examined mostly men. This study evaluated gender differences in and the degree to which social support was associated with life. Methods A sample 536 (35% women) recruited during a 14-month period from inpatient cardiology service University-based hospital. Participants completed assessments at baseline 3-month intervals over subsequent 12 months, for total 5 assessments. Measures each assessment included [Mental Component...
Ketamine research in depression has mostly used intravenous, weight-based approaches, which are difficult to translate clinically. Intranasal (IN) ketamine is a promising alternative but no controlled data been published on the feasibility, safety and potential efficacy of repeated IN treatments.This randomised, double-blind, placebo-controlled pilot study compared 4-week course eight treatments 100 mg or 4.5 midazolam. Each treatment was given as 10 separate sprays, self-administered 5 min...
To report a case of hypomania induced by transcranial direct current stimulation (tDCS) given with an extracephalic reference electrode. Transcranial is noninvasive brain technique in which weak applied through the scalp to produce changes neuronal excitability underlying cerebral tissue. Recent clinical trials have shown promising results left anodal prefrontal tDCS treating depression. When cathodal electrode moved from cranium position, larger areas both hemispheres are stimulated,...