A5100399450- Tea Polyphenols and Effects
- Plant Gene Expression Analysis
- Microbial Metabolism and Applications
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- melanin and skin pigmentation
- RNA modifications and cancer
- Chromosomal and Genetic Variations
- Fungal Infections and Studies
- Birth, Development, and Health
- Fungal and yeast genetics research
- Traditional Chinese Medicine Studies
- Renal and related cancers
- Pharmacological Effects of Natural Compounds
- Prenatal Screening and Diagnostics
- Plant Disease Resistance and Genetics
- Fungal Biology and Applications
- Acne and Rosacea Treatments and Effects
- CRISPR and Genetic Engineering
- Plant-Microbe Interactions and Immunity
- Phytochemicals and Antioxidant Activities
South China Agricultural University
2022-2024
Guangxi Medical University
2024
Shanghai First Maternity and Infant Hospital
2016-2018
Genomatica (United States)
2013
University of California, Berkeley
2013
Abstract Vegetative fusion is essential for the development of an interconnected colony in many filamentous fungi. In ascomycete fungus Neurospora crassa, vegetative occurs between germinated conidia (germlings) via specialized structures termed “conidial anastomosis tubes” (CATs) and hyphae within a mature colony. N. both CAT hyphal are under regulation conserved MAP kinase cascade (NRC1, MEK2, MAK2). Here we show that predicted downstream target MAK2 pathway, Ste12-like transcription...
Sall4 (Splat-like 4) plays important roles in maintaining pluripotency of embryonic stem cells and various developmental processes. Here, we find that is highly expressed oocytes early embryos. To investigate the SALL4 oogenesis, generated maternal specific knock-out mice by using CRISPR/Cas9 system, deletion causes arrest at germinal vesicle stage with non-surrounded nucleus, subsequent meiosis resumption prohibited. We further discover loss failure establishment DNA methylation oocytes....
The R2R3-MYB transcription factor (TF) family regulates metabolism of phenylpropanoids in various plant lineages. Species-expanded or specific MYB TFs may regulate species-specific metabolite biosynthesis including phenylpropanoid-derived bioactive products. Camellia sinensis produces an abundance specialized metabolites, which makes it excellent model for digging into the genetic regulation plant-specific biosynthesis. most abundant health-promoting metabolites tea are galloylated...
Abstract Talaromyces marneffei (TM) immune evasion is an important factor leading to the high mortality rate of Penicilliosis marneffei. N 6 ‐methyladenosine (m A) plays roles in host response various pathogen infections, yet its role TM and HIV/TM coinfection remains largely unexplored. Here we reported genome‐wide transcriptional m A profiles mono‐infection coinfection. Our finding revealed dynamic alterations global levels upregulation reader YTH RNA binding protein C2 (YTHDC2)...
Acne is a kind of multi-factor and multi-system disease.The pathogenesis acne relatively complex, which mainly believed to be related endocrine factors, abnormal keratosis hair follicle sebaceous duct microbial infection.However, the exact etiology are not clear yet.Recent studies suggest that dysregulation skin microbiome may involved in pathophysiology acne.At same time, intestinal microbiota also acne.This paper reviews relationship between acne, as well research on TCM treatment based this.