A5101700367- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Gut microbiota and health
- Mitochondrial Function and Pathology
- Pancreatic and Hepatic Oncology Research
- Vitamin C and Antioxidants Research
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer-related molecular mechanisms research
- Crystallography and molecular interactions
- Electrolyte and hormonal disorders
- Dental Implant Techniques and Outcomes
- RNA modifications and cancer
- Liver Disease Diagnosis and Treatment
- Cardiac Health and Mental Health
- MicroRNA in disease regulation
- Estrogen and related hormone effects
- Cancer survivorship and care
- Acute Ischemic Stroke Management
- Ovarian function and disorders
- Galectins and Cancer Biology
- Immune cells in cancer
- Cancer Risks and Factors
- Enzyme Catalysis and Immobilization
University of Minnesota
2010-2025
Shanxi Medical University
2022-2024
University of Minnesota System
2024
Shaanxi Provincial People's Hospital
2022-2024
Sun Yat-sen Memorial Hospital
2023
Sun Yat-sen University
2008-2023
Peking University
2022
Sichuan Cancer Hospital
2022
University of Electronic Science and Technology of China
2022
Second Affiliated Hospital of Xi'an Jiaotong University
2005-2021
It has been suggested that exercise following breast cancer diagnosis is inversely associated with mortality. However, controversy exists regarding the causality of such associations. We evaluated associations after total mortality and recurrence/disease-specific mortality, accounting for conditions restrict participation. The analysis included 4,826 women stage I to III identified 6 months through population-based Shanghai Cancer Registry recruited into study between 2002 2006. Exercise was...
Circulating RNAs in serum, plasma or other body liquid have emerged as useful and highly promising biomarkers for noninvasive diagnostic application. Herein, we aimed to establish a serum long non-coding (lncRNAs) signature diagnosing nasopharyngeal carcinoma (NPC). In this study, recruited cohort of 101 NPC patients, 20 patients with chronic nasopharyngitis (CN), EBV carriers (EC) healthy controls. qRT-PCR was performed cells samples screen pool 38 NPC-related lncRNAs obtained from the...
The inflammatory response is an unavoidable process and contributes to the destruction of cerebral tissue during acute ischemic stroke (AIS) phase has not been addressed fully date. Insightful understanding correlation mediators outcome may provide new biomarkers or therapeutic approaches for stroke. Here, we prospectively recruited 180 first-ever AIS patients within 72 hrs after onset. We used National Institutes Health Stroke Scale (NIHSS) quantify severity modified Rankin scale (mRS)...
Abstract Mitochondrial function is vital for energy metabolism in thermogenic adipocytes. Impaired mitochondrial bioenergetics brown adipocytes are linked to disrupted thermogenesis and balance obesity aging. Phospholipid cardiolipin (CL) phosphatidic acid (PA) jointly regulate membrane architecture dynamics, with mitochondria-associated endoplasmic reticulum membranes (MAMs) serving as the platform phospholipid biosynthesis metabolism. However, little known about regulators of MAM their...
Background: Lipocalin 2 (LCN2), also known as neutrophil gelatinase-associated lipocalin, is a 25 kDa protein involved in immune defense, inflammation, and metabolism. Results: LCN2 widely expressed across various tissues, including cells, bone, adipose tissue, liver, kidneys, lung, spleen, epithelial exhibits sex- fat depot-specific expression patterns. Structurally, contains hydrophobic lipid-binding pocket glycosylation sites, enabling it to interact with diverse ligands form dimers. In...
The purpose of this study was to investigate the relationships between sleep onset latency (SOL) and other sleep-wake patterns media use habits in Japanese schoolchildren. A total 9,718 junior high school children responded (12.8 years) 9199 questionnaires were used present analyses. questionnaire assessed patterns, TV viewing videogame habits. Overall, 72.1% subjects reported short SOL (<or=20 min). Long (>20 min) strongly associated with disturbed manifested especially by increased risk...
We assessed weight change from diagnosis to approximately 18 mo after cancer and evaluated its correlates in a large, population-based, cohort study of women diagnosed with stage 0–IV breast cancer. A total 4,561 cases information 1 yr prior diagnosis, at the 18-mo postdiagnosis interview were included study. Multinomial logistic regression models conducted examine association sociodemographic, clinical, lifestyle factors. The mean was gain 1.7 kg (median: 2.0). Overall, 61% gained weight,...
We have previously characterized lipocalin 2 (Lcn2) as a new adipokine having critical role in energy and lipid metabolism male mice. Previous studies by others suggested that Lcn2 is putative target gene of estrogens. In this study, we reported the effect deficiency on estradiol biosynthesis estrogen receptor signaling female Lcn2-deficient (Lcn2-/-) found expression white adipose tissue gender, depot, age dependent. mice, predominantly expressed inguinal but at relatively very low levels...
The elevation of circulating LPS has been associated with obesity and aging. However, whether how contributes to adipose tissue dysfunction is unclear. In this study, we investigated the effect on adipogenic capacity cellular senescence adipocyte progenitors. Stromal-vascular cells were isolated from inguinal C57BL/6 mice treated during different time periods differentiation. We found that treatment for 24 h prior induction differentiation led most profound inhibition adipogenesis, as...
Time-restricted feeding (TRF) is known to be an effective strategy for weight loss and metabolic health. TRF’s effect on metabolism complex likely acts various pathways within multiple tissues. Adipose tissue plays a key role in systemic homeostasis of glucose lipid metabolism. dysregulation has been causally associated with disorders obesity. However, it largely unknown how TRF impacts such as lipolysis, lipogenesis, thermogenesis different adipose depots To determine this, we conducted...
AIM:To explore expression and distribution features of COX-2 bcl-2 in human gastric adenocarcinoma tissues to study its biological significance. METHODS:Totally 36 carcinoma samples were enrolled this (cardiac 16 cases, distal 20 cases).The expressions cancerous corresponding para-cancerous investigated by immunohistochemistry using polyclonal antibody monoclonal antibody.The normal mucosa used as control. RESULTS:The significantly higher than that the paracancerous (77.8% vs 47.2%, P<0.01,...
Microbes are social organisms that commonly live in sessile biofilms. Spatial patterns of populations within biofilms can be important determinants community-level properties. intermixing emerging from microbial interaction is one the best-studied characteristics spatial patterns. The specific levels critically contribute to how dynamics and functioning such communities governed. However, precise factors determine remain unclear. Here, we investigated patterning an engineered synthetic...
Lipomas are ubiquitous and can occur anywhere in the body. Intrathoracic lipomata rare benign lesions. However, a complete removal giant intrathoracic osteolipoma is achieved with only 18 cases previous described medical literature from 1960 to 2008.A 66-year-old female presented our hospital suffered mild chest pain shortness of breath for more than 10 days. A subsequent X-ray CT scans revealed large homogeneous, low-attenuation fat density mass containing an oval calcification area center...
Abstract Background The new Chinese fertility policy has recently received widespread public attention. However, there are few studies available on the comprehensive epidemiology of maternal and infant health with respect to characteristic changes childbearing women. In study, we compared characteristics pregnancy outcomes at different time points according adjustments, accessed possible relationship among these factors, evaluated impacts policies for medical assistance. Methods This was a...
Objective To assess whether the administration of Zishen Yutai Pill (ZYP) could improve pregnancy outcomes in different subgroups women undergoing fresh embryo transfer cycles. Materials and methods This is a post hoc analysis large scale, placebo-controlled, double blind, randomized clinical trial (RCT) regarding use ZYP during assisted reproductive technology (ART) treatment. The RCT was conducted at 19 vitro fertilization (IVF) centers between April 2014 June 2017. A total 2265 cycles...