- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Listeria monocytogenes in Food Safety
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Food Safety and Hygiene
- Clostridium difficile and Clostridium perfringens research
- Bacteriophages and microbial interactions
- Fecal contamination and water quality
- Veterinary Equine Medical Research
- Mycobacterium research and diagnosis
- Antibiotic Use and Resistance
- Microbial infections and disease research
- Bacterial Identification and Susceptibility Testing
- Mesenchymal stem cell research
- Osteoarthritis Treatment and Mechanisms
- COVID-19 epidemiological studies
- Veterinary Orthopedics and Neurology
- Escherichia coli research studies
- Viral Infections and Vectors
- Gastrointestinal disorders and treatments
- Genomics and Phylogenetic Studies
- Veterinary Pharmacology and Anesthesia
- Animal Disease Management and Epidemiology
Cornell University
2015-2025
New York State College of Veterinary Medicine
2009-2023
Texas A&M University
2012-2019
Texas College
2016
Mitchell Institute
2013
Washington State University
2012
Washington State Department of Health
2012
New York State Department of Health
2012
University of California, Irvine
2012
California Department of Public Health
2008
Intra-articular injection of mesenchymal stem cells (MSCs) is efficacious in osteoarthritis therapy. A direct comparison the response synovial joint to intra-articular autologous versus allogeneic MSCs has not been performed. The objective this study was assess clinical repeated prepared a way minimize xeno-contaminants large animal model.Intra-articular injections bone marrow-derived, culture-expanded forelimb metacarpophalangeal were performed at week 0 and 4 (six autologous; six with...
The dog represents an excellent large animal model for translational cell-based studies. Importantly, the properties of canine multipotent stromal cells (cMSCs) and ideal tissue source specific studies have yet to be established. aim this study was characterize cMSCs derived from synovium, bone marrow, adipose using a donor-matched design comprehensive series in-vitro characterization, differentiation, immunomodulation assays. Canine MSCs were isolated five dogs with cranial cruciate...
Background There is little information on the epidemiology of enteric pathogens in Lebanon, a low- and middle-income country that suffers from myriad public health challenges. To address this knowledge gap, we aimed to assess prevalence pathogens, identify risk factors seasonal variations, describe associations between among diarrheic patients Lebanese community. Methodology principal findings A multicenter cross-sectional community-based study was conducted north Lebanon. Stool samples were...
The objective of this study was to determine if the within-herd prevalence fecal Salmonella shedding is higher in dairy herds with clinical outbreaks disease, as compared subclinical infections only. Data were collected prospectively from throughout New York that had at least 150 lactating cows and received service participating veterinarians. After enrollment, surveillance consisted both environmental screening disease monitoring within herd. Herds positive by either or culture sampled...
Monitoring antimicrobial resistance trends among bacteria isolated from food animals and people is necessary to inform risk analyses guide public policy regarding use. Our objectives were describe the status of Escherichia coli isolates dairy cattle in northeastern United States identify selected agents over time. We collected data retrospectively for all bovine E. that obtained samples submitted Cornell University's Animal Health Diagnostic Center between January 1, 2004 December 31, 2011....
Background Vector‐borne diseases have an adverse impact on health of dogs, and infected dogs can be sentinels for human infection. Infection with Trypanosoma cruzi , agent Chagas disease, causes fatal heart disease in across the southern United States but has been neglected from wide‐scale prevalence studies. Objectives To determine exposure to T. Ehrlichia spp., Anaplasma Borrelia burgdorferi infection Dirofilaria immitis among shelters Texas identify risk factors seropositivity. Animals...
Opportunistic invasive fungal infections (OIFIs) occur in dogs administered immunosuppressive medications. However, the epidemiology of OIFIs among undergoing treatment is poorly understood. The aims this study were to (1) estimate incidence diagnosed with certain immune-mediated diseases and treated drugs, (2) determine if administration particular drug(s) was a risk factor for OIFIs.Dogs receiving cyclosporine (alone or as part multidrug protocol) are at higher developing OIFIs.One hundred...
Wars have hidden repercussions beyond the immediate losses of life, well-being, and prosperity. Those that flee wars seek refuge in safer locations are not immune to tragic impacts. Of particular concern is susceptibility refugee populations infectious diseases antimicrobial-resistant pathogens. This poses a detrimental risk these disenfranchised populations, who often limited access medical care, sanitation, nutritious safe food. Furthermore, pathogens refugees can be both transmitted...
We investigated an outbreak of Salmonella Enteritidis (SE) infections linked to raw mung bean sprouts in 2000 with two case-control studies and reviewed six similar outbreaks that occurred 2000-2002. All were due unusual phage types (PT) SE the United States (PT 33, 1, 913), Canada 11b The Netherlands 4b). PT 33 was spent irrigation water a drain from one sprout grower. None growers disinfected seeds at recommended concentrations. Only tested water; neither discarded implicated seed lots...
The focus of this study was Salmonella enterica serotype Cerro, a potentially emerging pathogen cattle. Our objectives were to document the within-herd prevalence Cerro among sample New York dairy herds, describe antimicrobial resistance patterns and pulsed-field gel electrophoresis types isolates, elucidate status as bovine pathogen. Data collected prospectively from herds throughout that had at least 150 lactating cows received clinical service participating veterinarians. Following...
Salmonella represents an important zoonotic pathogen worldwide, but the transmission dynamics between humans and animals as well within animal populations are incompletely understood. We characterized isolates from cattle in two geographic regions of United States, Pacific Northwest Northeast, using three common subtyping methods (pulsed-field gel electrophoresis [PFGE], multilocus variable number tandem repeat analysis [MLVA], sequence typing [MLST]). In addition, we analyzed distribution...
Salmonellosis is usually associated with foodborne transmission. To identify risk from animal contact, we compared exposures of case-patients infected bovine-associated Salmonella subtypes those control-patients non-bovine-associated subtypes. We used data collected in New York and Washington, USA, March 1, 2008, through 2010. Contact farm animals during the 5 days before illness onset was significantly being a case-patient (odds ratio 3.2, p = 0.0008), after consumption undercooked ground...
Abstract Background Combatting antimicrobial resistance requires a One Health approach to stewardship including drug (AMD) use evaluation. Current veterinary AMD prescribing data are limited. Objectives To quantify companion animal in primary care and specialty practice across 3 academic hospitals with particular focus on third‐generation cephalosporins, fluoroquinolones, carbapenems. Animals Dogs cats presented from 2012 2017. Methods In this retrospective study, 2017 were extracted...
Salmonella Cerro has become one of the most prevalent serotypes isolated from dairy cattle in several U.S. states. It frequently causes disease cattle, resulting decreased milk yield and increased economic burden for farmers. To better understand transmission patterns drivers its geographic spread, we have studied genomic similarity microevolution S. isolates northeast Texas. We identified core genome SNPs 57 upstate New York (NY), 2 Pennsylvania (PA), 27 Texas farm environments, raw milk,...
Monitoring antimicrobial resistance trends among bacteria isolated from food animals and people is necessary to inform public policy regarding appropriate use. Our objectives were describe the status of Salmonella isolates dairy cattle in northeastern United States identify various agents over time. Data collected retrospectively for all bovine that obtained samples submitted Cornell University's Animal Health Diagnostic Center between January 1, 2004 December 31, 2011. Temporal prevalence...
Dairy cattle are a reservoir of several Salmonella serovars that leading causes human salmonellosis. The objectives this study were to estimate the environmental prevalence on dairy farms in Texas and characterize antimicrobial susceptibility isolates. Eleven throughout sampled from August through October 2013, using cross-sectional approach. Samples collected four locations within each farm (hospital pen, maternity cow housing area, calf area), feces cull cows as available. Environmental...
Summary Estimates of prevalence faecal Salmonella shedding among dogs in the United States have varied widely. Surveillance shelter has been limited, although animal shelters may be at elevated risk infection because their previous exposure history as well factors inherent to environments. Our objectives were estimate across Texas, identify for and characterize isolates. Using a repeated cross‐sectional study design, we collected samples from on two or three visits each seven Texas between...