- COVID-19 Clinical Research Studies
- Clinical Reasoning and Diagnostic Skills
- Cancer Immunotherapy and Biomarkers
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Innovations in Medical Education
- COVID-19 and healthcare impacts
- Respiratory Support and Mechanisms
- Radiology practices and education
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Patient Safety and Medication Errors
- Technology and Data Analysis
- Antibiotic Use and Resistance
- Venous Thromboembolism Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- Pneumonia and Respiratory Infections
- Diverse Approaches in Healthcare and Education Studies
- Respiratory viral infections research
- Energy and Environmental Systems
- Patient-Provider Communication in Healthcare
- Nosocomial Infections in ICU
- Medical Malpractice and Liability Issues
- Chronic Obstructive Pulmonary Disease (COPD) Research
Cornell University
2015-2025
Weill Cornell Medicine
2020-2025
Hamad Medical Corporation
2024
Weill Cornell Medical College in Qatar
2024
Maastricht University
2023
Presbyterian Hospital
2017-2022
Michael E. DeBakey VA Medical Center
2022
Baylor College of Medicine
2022
West Virginia University
2019-2021
Presbyterian Healthcare Services
2020
To characterize patients with coronavirus disease 2019 (covid-19) in a large New York City medical center and describe their clinical course across the emergency department, hospital wards, intensive care units.Retrospective manual record review.NewYork-Presbyterian/Columbia University Irving Medical Center, quaternary academic City.The first 1000 consecutive positive result on reverse transcriptase polymerase chain reaction assay for severe acute respiratory syndrome 2 (SARS-CoV-2) who...
A surge of patients with coronavirus disease 2019 (COVID-19) presenting to New York City hospitals in March 2020 led a sharp increase blood culture utilization, which overwhelmed the capacity automated instruments. We sought evaluate utilization and diagnostic yield cultures during COVID-19 pandemic determine prevalence common etiologies bacteremia inform approach relieve overutilization. performed retrospective cohort analysis 88,201 from 28,011 at multicenter network within order volume,...
Abstract Objective To characterize patients with coronavirus disease 2019 (COVID-19) in a large New York City (NYC) medical center and describe their clinical course across the emergency department (ED), inpatient wards, intensive care units (ICUs). Design Retrospective manual record review. Setting NewYork-Presbyterian/Columbia University Irving Medical Center (NYP/CUIMC), quaternary academic NYC. Participants The first 1000 consecutive laboratory-confirmed COVID-19. Methods We identified...
Abstract Background The spread of SARS-CoV-2 and the COVID-19 pandemic have caused significant morbidity mortality worldwide. clinical characteristics outcomes hospitalized patients with HIV co-infection remain uncertain. Methods We conducted a matched retrospective cohort study adults illness in New York City between March 3, 2020, May 15, 2020. 30 people (PWH) 90 control group without based on age, sex, race/ethnicity. Using electronic health record data, we compared demographic...
3D silicon carbide structures are patterned via direct ink writing (DIW) of borosiloxane-colloidal SiC blends. These hybrid inks enable printing over a wide range colloidal volume fractions (0.38 < ɸ 0.54) to produce relative densities ≈30–50%. Structural (bars, cylinders, turbines) and functional (periodic lattices, microwave feedhorns) components printed sintered with excellent shape stability. The feedhorns transmit microwaves (8.5 GHz) very low insertion losses (≈0.05 dB) commercial...
Increasing evidence has shown that Coronavirus disease 19 (COVID-19) severity is driven by a dysregulated immunologic response. We aimed to assess the differences in inflammatory cytokines COVID-19 patients compared contemporaneously hospitalized controls and then analyze relationship between these development of Acute Respiratory Distress Syndrome (ARDS), Kidney Injury (AKI) mortality. In this cohort study patients, done March third, 2020 April first, at quaternary referral center New York...
Admissions for acute bacterial skin and structure infections (ABSSSI) are often prolonged because of intravenous (IV) antibiotics. Use a long-acting IV antibiotic may reduce length stay (LOS) on hospitalist service. The ENHANCE ABSSSI trial sought to determine the impact LOS work productivity in patients treated with antibiotic, dalbavancin, vs. usual care at an urban tertiary-care center. A single-center, pre- post-period pragmatic Weill-Cornell Medical Center assessed consecutively...
Antimicrobial peptides (AMPs) constitute an important part of innate host defense. Possibly limiting the therapeutic potential AMPs is fact that bacteria have developed AMP resistance mechanisms during their co-evolution with humans. However, there no direct evidence per se infection. Here we show Staphylococcus aureus Pmt ABC transporter defends from killing by human and elimination neutrophils. By showing contributes to virulence skin infection in AMP-dependent manner, provide plays a key...
Background Severe acute respiratory coronavirus 2 (SARS-CoV-2) has caused a devastating worldwide pandemic. Hydroxychloroquine (HCQ) in vitro activity against SARS-CoV-2, but clinical data supporting HCQ for disease 2019 (COVID-19) are limited. Methods This was retrospective cohort study of hospitalized patients with COVID-19 who received ≥1 dose at two New York City hospitals. We measured incident Grade 3 or 4 blood count and liver test abnormalities, ventricular arrhythmias, vomiting...
The coronavirus disease-19 (COVID-19) pandemic has ravaged global healthcare with previously unseen levels of morbidity and mortality. In this study, we performed large-scale integrative multi-omics analyses serum obtained from COVID-19 patients the goal uncovering novel pathogenic complexities disease identifying molecular signatures that predict clinical outcomes. We assembled a network protein-metabolite interactions through targeted metabolomic proteomic profiling in 330 compared to 97...
Abstract Background The COVID-19 pandemic required clinicians to care for a disease with evolving characteristics while also adhering changes (e.g., physical distancing practices) that might lead diagnostic errors (DEs). Objective To determine the frequency of DEs and their causes among patients hospitalized under investigation (PUI) COVID-19. Design Retrospective cohort. Setting Eight medical centers affiliated Hospital Medicine ReEngineering Network (HOMERuN). Target population Adults...