- Satellite Communication Systems
- Advanced Glycation End Products research
- Wireless Communication Networks Research
- Advanced Wireless Communication Techniques
- Fungal Biology and Applications
- Redox biology and oxidative stress
- Microbial Natural Products and Biosynthesis
- Mass Spectrometry Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Physical Education and Pedagogy
- Fungal and yeast genetics research
- Metal-Catalyzed Oxygenation Mechanisms
- Heat shock proteins research
- Glutathione Transferases and Polymorphisms
- Wireless Networks and Protocols
- Network Traffic and Congestion Control
- Insect Utilization and Effects
- Healthcare Policy and Management
- Parasites and Host Interactions
- Parasitic Diseases Research and Treatment
- Mycotoxins in Agriculture and Food
- Telecommunications and Broadcasting Technologies
- Transgenic Plants and Applications
- Identification and Quantification in Food
- Radiation Effects in Electronics
University of Bristol
1981-2020
Waltham Centre for Pet Nutrition
2013-2019
University of Otago
2016
Mitre (United States)
2000-2008
Excelsior College
2005
Signal Processing (United States)
2002
MACOM (United States)
1987
Photorhabdus is a virulent pathogen that kills its insect host by overcoming immune responses. The bacterium also secretes range of antibiotics to suppress the growth other invading microorganisms. Here we show produces small-molecule antibiotic ( E )-1,3-dihydroxy-2-(isopropyl)-5-(2-phenylethenyl)benzene (ST) acts as an inhibitor phenoloxidase (PO) in Manduca sexta . gene stlA encodes enzyme cinnamic acid, key precursor for production ST, and mutation results loss ST PO inhibitory activity,...
Reactions between sugars and amino acids in the Maillard reaction produce a multitude of compounds through interconnected chemical pathways. The course pathways changes depending on nature as well processing conditions (e.g. temperature, water activity). Some partial have been elucidated using labelled precursors but process is very time intensive. Here, we use rapid, non-targeted analysis with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) to deliver molecular...
In this study, we monitored the thermal formation of early ribose-glycine Maillard reaction products over time by ion cyclotron resonance mass spectrometry. Here, considered sugar decomposition (caramelization) apart from compounds that could only be produced in presence amino acid. More than 300 intermediates as a result two initial reactants were found after ten hours (100 °C) to participate interplay cascade. Despite large numerical variety majority follow simple and repetitive patterns....
Abstract The tenS gene encoding tenellin synthetase (TENS), a 4239‐residue polyketide synthase nonribosomal‐peptide (PKS‐NRPS) from Beauveria bassiana , was expressed in Aspergillus oryzae M‐2‐3. This led to the production of three new compounds, identified as acyl tetramic acids, and numerous minor metabolites. Consideration structures these compounds indicates that putative C‐terminal thiolester reductase (R) domain does not act reductase, but appears Dieckmann cyclase (DKC). Expression...
Heterologous expression of key components the <italic>Magnaporthe grisea ACE1</italic> gene cluster produces a potential precursor cryptic avirulence signalling compounds that induce resistance to <italic>M. grisea</italic> in rice.
A retrospective medical record review was conducted to identify factors from veterinary clinic records that may have contributed suspected ineffectiveness of a heartworm preventive product. Patient 271 dogs, comprising 301 instances positive antigen test results while the dogs were receiving evaluated. Nineteen practices in 17 counties and parishes Arkansas, Louisiana, Mississippi, Tennessee participated study. Records selected by clinics as representative cases lack effectiveness for...
FSN1, a gene isolated from the sugar-cane pathogen Fusarium sacchari, encodes 4707-residue nonribosomal peptide synthetase consisting of three complete adenylation, thiolation and condensation modules followed by two additional domain repeats. This structure is similar to that ferricrocin synthetase, which makes siderophore involved in intracellular iron storage other filamentous fungi. Heterologous expression FSN1 Aspergillus oryzae resulted accumulation secreted metabolite was identified...
NOE–distance relationships are shown to be sufficiently accurate monitor very small changes in conformer populations response temperature (<0.5%/10 °C) – good agreement with Boltzmann-predictions.
The photochemical transformation of Maillard reaction products (MRPs) under simulated sunlight into mostly unexplored photoproducts is reported herein. Non-enzymatic glycation amino acids leads to a heterogeneous class intermediates with extreme chemical diversity, which particular relevance in processed and stored food as well diabetic age-related protein damage. Here, three (lysine, arginine, histidine) were reacted ribose at 100 °C water for ten hours. Exposing these model systems led...
Phosphorus (P) is an essential nutrient; however, potential health impacts of high dietary levels added soluble, highly bioavailable P salts especially are a concern. sources with lower bioavailability considered safer. Yet, speciation different to assess diets' risk challenging. This investigation tested the value in vitro water extraction and digestion assays predict vivo apparent bioavailability/digestibility feline diets. Thirty wet (n = 18) dry 12) format experimental commercial cat...
Fusarochromene isolated from the plant pathogenic fungus, Fusarium sacchari is closely related to a group of mycotoxins including fusarochromanone previously various Fusaria spp. Despite their assumed polyketide biogenesis, incorporation studies with 13C-labelled acetate, glycerol and tryptophans show that fusarochromene unexpectedly derived via oxidative cleavage aromatic amino acid tryptophan. A putative biosynthetic gene cluster has been identified.
Identification of chemically modified peptides in mass spectrometry (MS)-based glycation studies is a crucial yet challenging task. There need to establish mode for matching tandem (MS/MS) data, allowing both known and unknown peptide modifications. We present an open search approach that uses classic fragment ions. The latter are shifted by the delta modification. Both provide key structural information can be used assess core structure product. also leverage redundant neutral losses from...
Wireless relays offer one approach to providing communications among small teams operating below-decks on neutral or hostile ships. Two sets of experiments were conducted aboard a container ship determine the viability this approach. In first set experiments, RF propagation loss and coherence bandwidth assessed in both 2.4 GHz 5.8 ISM bands. second set, packet latency throughput for 802.11a 802.11b networks multihop configurations with hidden nodes. On basis these it is concluded that...
Solid-state magic angle spinning 31P NMR spectroscopy is used to identify and quantify phosphorus-containing species in pet foods. The measurement challenging due the long spin-lattice relaxation times (T1s). Data acquisition are shortened by acquiring data with a tip smaller than 90° shortening repetition time. However, (T1s) of different compounds quite different, necessitating separate for each compound food. Knowledge T1 calculate relative amount samples. Samples known concentration also...
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Military procurement philosophy is currently evolving toward the use of commercial off-the-shelf (COTS) products to reduce cost taxpayer and provide military users with advanced technology. Meanwhile, asynchronous transfer mode (ATM) are being developed implemented in communications networks. This technology rapidly progressing international standardization. Furthermore, promises offer multimedia services potential interoperation among different networks by multiplexing all offered traffic...
Peptide glycation is an important, yet poorly understood reaction not only found in food but also biological systems. The enormous heterogeneity of peptides and the complexity reactions impeded large-scale analysis peptide derived products to understand both contributing factors how this affects activity peptides. Analyzing time-resolved Amadori product formation, we here explored site-specific for 264 Intensity profiling together with in-depth computational sequence deconvolution resolved...
This paper determines the link performance of Global Broadcast Service (GBS) when it is transitioned to Wideband SATCOM (WGS) satellites. Current and future (smaller) GBS terminals as well current Digital Video Broadcast-Satellite (DVB-S) (DVB-S2) Modems are considered. DVB-S2 provides a large increase in capability terms modulations forward error correcting coding rates. In addition, allows for different using variable modulation (different streams coded with different, fixed parameters...
summary This article presents an overview of the conditioning requirements rugby union, followed by a sample yearly strength periodization plan. plan focuses on core group techniques, with supplemental techniques rotated in phases.