A5014774668- Global Maternal and Child Health
- Child Nutrition and Water Access
- Colorectal Cancer Screening and Detection
- Viral gastroenteritis research and epidemiology
- Vaccine Coverage and Hesitancy
- Healthcare Systems and Reforms
- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Congenital Heart Disease Studies
- Child Nutrition and Feeding Issues
- Acne and Rosacea Treatments and Effects
- AI in cancer detection
- Cardiovascular Issues in Pregnancy
- Diverticular Disease and Complications
- Adolescent and Pediatric Healthcare
- Phonocardiography and Auscultation Techniques
- Cardiovascular Conditions and Treatments
- Gastric Cancer Management and Outcomes
- Infant Health and Development
- COVID-19 diagnosis using AI
- Colorectal and Anal Carcinomas
- Probiotics and Fermented Foods
- Breast Cancer Treatment Studies
- COVID-19 Impact on Reproduction
- Craniofacial Disorders and Treatments
Aga Khan University
2020-2024
Aga Khan University Hospital
2021-2022
Importance In resource-constrained settings where the neonatal mortality rate (NMR) is high due to preventable causes and health systems are underused, community-based interventions can increase newborn survival by improving care practices. Objectives To develop evaluate effectiveness of a maternal services package reduce perinatal in rural Pakistan. Design, Setting, Participants This cluster randomized clinical trial was conducted between November 1, 2012, December 31, 2013, district Rahim...
Diarrhoea is a leading cause of preventable childhood morbidity and mortality worldwide. Unfortunately, Pakistan has the third-highest burden diarrhoea-related deaths in children <5 y age. Therefore we aimed to evaluate factors associated with diarrhoea among Pakistani children.A retrospective 1:2 matched case-control study nested baseline cross-sectional survey was conducted from October December 2018 Taluka Kotri, two-thirds urban locality Jamshoro district. Children between ages 0 23...
Objective: To evaluate the impact of a quality improvement (QI) initiative, which included Fluconazole prophylaxis protocol and provider education on neonatal Candidiasis. Study Design: Retrospective longitudinal study. Place Duration Study: Neonatal Intensive Care Unit (NICU), Aga Khan University, Karachi Pakistan, from Apr 2015 to Dec 2019. Methodology: All extremely low birth weight neonates (ELBW) admitted NICU between April March 2017 were in pre-implementation phase. ELBW December 2019...
Cleft palate repair is considered to be a safe procedure, yet still carries 5% 30% risk of complications. This study sought assess the outcomes this procedure in high-burden Asian country that partners with Smile Train perform cleft surgeries.The Aga Khan University medical records database was queried for pediatric patients undergoing surgery between 2014 and 2017. Data were abstracted from patient records, details clinical, demographic factors, postoperative assessed.Among 142 orofacial...
The conventional IMCI training for healthcare providers is delivered in 11 days, which can be expensive and disruptive to the normal clinical routines of providers. An equally effective, shorter course may address these challenges.We conducted a quasi-experimental study two provinces (Sindh Punjab) Pakistan. 104 were conveniently selected receive either abridged (7-day) or standard (11-day) training. Knowledge skills participants assessed before, immediately on conclusion of, six months...
Abstract Introduction: Primary signet ring cell carcinoma (SRCC) is a rare variant of colorectal cancer, reportedly comprising 0.1%-2.6% all cancers. Due to manifestations occurring later in the course disease, overall survival poorer than that adenocarcinoma. The Southeast Asian region has been observed have higher likelihood having variant. Objective: following study determines proportion and histopathological characteristics cancer Pakistani population across tertiary care hospital....
Nutrition societies recommend using standardised parenteral nutrition (SPN) solutions. We designed evidence-based SPN formulations for neonates admitted to our neonatal intensive care unit (NICU) and evaluated their outcomes.This was a quality improvement initiative. Data were collected retrospectively before after the intervention.A tertiary-care level 3 NICU at Aga Khan University in Karachi, Pakistan.All patients who received individualised PN (IPN) from December 2016 August 2017 October...
Background: We aimed to describe the outcomes of neonates born at or near term women undergoing elective C-section without prophylactic corticosteroids. Methods: Single-centre retrospective observational study between 36+0 and 42+0 weeks. Associations neonatal complications maternal factors were evaluated by univariate analyses multivariate logistic regression. Results: A total 2151 (26%) during period, whom 429 included in study. Fifty-six (13.05%) developed some complication with 39 (9.1%)...
Infants are at a higher risk of severe illness with COVID-19 infection compared to older children. While vaccination is not recommended for young infants, they can acquire maternally-derived anti-SARS-CoV-2 antibodies passively through the placenta and breastmilk. We described persistence infection-induced maternal in infant circulation 9-12 months age.
Background and Objective: Breast-conserving surgery (BCS) with adjuvant radiotherapy remains the standard of care for early breast cancers in Pakistan. We sought to compare outcomes BCS oncoplastic (OPS), a relatively infrequent approach cancer treatment country.
 Methods: This retrospective cohort study was conducted at Aga Khan University Hospital Ziauddin Karachi. Patients who had biopsy-proven Stage-I III underwent either OPS or between August 1, 2016, December 31, 2021, were...
Abstract Background: The conventional IMCI training for healthcare providers is delivered in 11 days, which can be expensive and disruptive to the normal clinical routines of providers. An equally effective, shorter course may address these difficulties. Methods: This was a quasi-experimental study that conducted two provinces (Sindh Punjab) Pakistan. 104 were conveniently selected receive either abridged (7-day) or standard (11-day) training. Knowledge skills participants assessed before,...
Background: Acne, or acne vulgaris, a chronic inflammatory disorder of the pilosebaceous unit skin, can severely affect an individual’s social and psychological functioning, progressing into psychiatric morbidity including anxiety, depression, decreased self-esteem. The objective this study was to determine frequency Anxiety, Depression Low Self-esteem in patients with Acne Vulgaris visiting dermatology clinics at tertiary care hospitals Karachi. Methods: This cross-sectional conducted on...