- COVID-19 and Mental Health
- Child and Adolescent Psychosocial and Emotional Development
- Child Abuse and Trauma
- HIV/AIDS Research and Interventions
- Hepatitis B Virus Studies
- HIV, Drug Use, Sexual Risk
- Maternal Mental Health During Pregnancy and Postpartum
- Digital Mental Health Interventions
- Pneumonia and Respiratory Infections
- HIV Research and Treatment
- Impact of Technology on Adolescents
- COVID-19 Pandemic Impacts
- Global Maternal and Child Health
- Family and Disability Support Research
- HIV/AIDS Impact and Responses
- Antibiotic Use and Resistance
- Intimate Partner and Family Violence
- Child Nutrition and Water Access
- Infant Development and Preterm Care
- HIV/AIDS drug development and treatment
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Bacterial Infections and Vaccines
- Cyberloafing and Workplace Behavior
- Neonatal and Maternal Infections
Aga Khan University Hospital Nairobi
2025
Institute for Clinical Evaluative Sciences
2023-2024
SickKids Foundation
2023-2024
Hospital for Sick Children
2023-2024
Aga Khan University
2019-2023
Bridge University
2021
Tabba Heart Institute
2021
Queensland University of Technology
2021
University Research Co (United States)
2021
University of Hertfordshire
1996-1998
Background: Acute respiratory infection (ARI) accounts for nearly 15% of all childhood mortality in South Asia, with children from rural areas at higher risk due to inaccessibility healthcare facilities. We therefore aimed identify factors associated ARI under 2 years age Pakistan. Methods: A retrospective 1:2 matched case-control study was conducted between October and December 2018 Taluka Kotri, Jamshoro District Cases were identified as 0 23 months a history fever, cough, sore throat,...
<title>Abstract</title> <bold>Introduction:</bold> Injections are frequently used in developing countries as a perceived potent medical treatment. However, unsafe injection practices, including the reuse of syringes without proper sterilization, can transmit infectious diseases like hepatitis B, C, and HIV. In Pakistan, average rate is 8.5 per person annually, with significant proportion deemed unnecessary. Cultural beliefs mutual reinforcement between healthcare providers patients...
Objective To describe the mental health trajectories of caregivers children with medical complexity (CMC) and explore child characteristics associated below-average caregiver health. Design A secondary analysis prospectively collected data from 123 aged <16 years a multicentre randomised trial conducted December 2016 to June 2021. Main outcome measure The Patient-Reported Outcomes Measurement Information System Global Mental Health Scale was used caregivers' self-reported well-being....
Data from the Global School-based Student Health Survey (GSHS) conducted in 2009 consisting of 5192 Pakistani school-going adolescents was used to assess association between parent-child-relationship and physical-aggression. A multilevel-weighted-cox-proportional-algorithm performed. The overall prevalence physical-aggression 41% which 27% had a poor parent-child relationship. Male who have bond with their parents two times (95% CI: 1.82, 3.00) than those female strong parent-child-bonding....
(1) Background: CMV and EBV co-infections can affect the HIV disease progression by modulating immune system. The dynamics differ in HIV-positive adults children. In Pakistan, is rapidly expanding, especially children; however, prevalence of co-infection effect on modulation children are not known. This study aimed to bridge this gap estimating rate active children, followed analysis differential expression cytokines mono- HIV/CMV/EBV co-infected (2) Methods: DNA samples from 319 previously...
In April 2019, an HIV-1 outbreak among children occurred in Larkana, Pakistan, affecting more than a thousand children. It was assumed that the originated from single source, namely doctor at private health facility. this study, we performed subtype distribution, phylogenetic and drug-resistance analysis of sequences 2019 Pakistan. A total 401 blood samples were collected between April-June infected with aged 0-15 years recruited into case-control study to investigate risk factors for...
Introduction In April 2019, 14 children were diagnosed with HIV infection by a private healthcare provider in Larkana district, Sindh province, Pakistan. Over the next 3 months, 930 individuals HIV, >80% below 16 years, largest ever outbreak of this protocol paper, we describe research methods for assessing likely modes transmission and investigate spatial molecular epidemiology. Methods analysis A matched case–control study will be conducted 406 cases recruited. Cases aged years...
Severe respiratory disease declined during the COVID-19 pandemic, partially due to decreased circulation of pathogens. However, outcomes children with higher risk have not been described using population-based data.
Diarrhoea is a leading cause of preventable childhood morbidity and mortality worldwide. Unfortunately, Pakistan has the third-highest burden diarrhoea-related deaths in children <5 y age. Therefore we aimed to evaluate factors associated with diarrhoea among Pakistani children.A retrospective 1:2 matched case-control study nested baseline cross-sectional survey was conducted from October December 2018 Taluka Kotri, two-thirds urban locality Jamshoro district. Children between ages 0 23...
The typically developing siblings of children with disabilities are vulnerable to behavioral problems as they grow up in an environment considerable stress. Yet, the needs and behavior these often neglected especially Pakistan. In this cross-sectional study, we assessed among developmental disabilities. strength difficulties questionnaire (SDQ) was administered on 250 (aged 6–17 years) a disability (Autism, Intellectual (ID), Down Syndrome (DS), Attention Deficit Hyperactive Disorder (ADHD))...
This study aims to determine the burden and factors associated with perceived stress in Pakistani population amidst COVID-19 pandemic.A web-based cross-sectional survey was conducted from April August 2020.This broadcasted on web using a Google form link 1654 residents had completed this survey. Individuals belonging any province, city, village, or district of Pakistan irrespective age, having internet access form, English/Urdu competency, consent participate, currently residing were...
Introduction Parents of children with developmental disabilities, particularly mothers, are likely to suffer from stress. Nevertheless, the association between parenting stress and type extent disability is far evident.Methods To examine relationship stress, disability, we collected demographic details Parenting Stress Scale 250 mothers a attending special-education schools in Karachi. Type were diagnosed by school's psychologist based on DSM criteria. Adjusted beta-coefficients along 95%...
This study aims to determine the burden of COVID19-induced internet addiction and related psychosocial factors among Pakistani sample. A web-based cross-sectional survey was conducted from January March 2021. An analytical broadcast on via a Google form completed by 1145 Pakistanis. Individuals aged 13 years above with competency comprehend English or Urdu language, currently residing in any province Pakistan, having access questionnaire, willing participate were eligible participate....
Abstract Background Parent-to-child maltreatment is considered one of the risk factors for Generalized Anxiety Disorder (GAD) symptoms, but this hypothesis has not been adequately tested in Pakistani settings. Aim This study aimed to examine association between parent-to-child and developing GAD symptoms among adolescents. Methods The none rare, occasionally, frequently with incidence was investigated a sample 800 adolescents aged 11–17 years who were followed two years. assessed using...
Abstract Objective Mothers whose newborn experiences adversity may neglect their own health to care for affected infant or following a perinatal death. Weight gain after pregnancy is one measure of maternal self‐care. We measured interpregnancy weight among women child had an adverse event. Methods This population‐based observational study included 192 154 primigravid with two consecutive singleton births in Ontario, Canada. Outcomes net gain, and adjusted odds ratios (aOR) moving higher...
Parent-to-child maltreatment has been demonstrated to drastically affect a child's mental well-being and plays significant role in developing depressive symptoms. However, little is established about the effect of frequency parent-to-child on development symptoms among Pakistani adolescents.A longitudinal prospective study was conducted, from 2015 2017, with 800 adolescents aged 11-17 years old recruited 32 systematically selected urban peri-urban areas Karachi. First, these were screened...
Abstract This study examined the effect of a mental well‐being module on undergraduate nursing students’ knowledge and beliefs regarding causes treatment health illness, explored relationship between these variables depression anxiety. The one group design incorporated pre‐intervention, intervention post‐intervention phases, in consecutive sample 246 students 4‐year BScN programme Pakistan. A culturally sensitive, interactive four hours length was delivered to three groups approximately 40...