A5034720772- Selenium in Biological Systems
- Plant Micronutrient Interactions and Effects
- Plant Stress Responses and Tolerance
- Hematopoietic Stem Cell Transplantation
- T-cell and B-cell Immunology
- Coal and Its By-products
- Photonic and Optical Devices
- Mercury impact and mitigation studies
- Microbial Community Ecology and Physiology
- Semiconductor materials and devices
- Semiconductor Quantum Structures and Devices
- Renal Transplantation Outcomes and Treatments
- Heavy Metals in Plants
- Integrated Circuits and Semiconductor Failure Analysis
- Kidney Stones and Urolithiasis Treatments
- Trace Elements in Health
- Heavy metals in environment
- Semiconductor Lasers and Optical Devices
- Moringa oleifera research and applications
- Genomics and Phylogenetic Studies
- Copper Interconnects and Reliability
- Soil Carbon and Nitrogen Dynamics
- Cytomegalovirus and herpesvirus research
- Terahertz technology and applications
- Aluminum toxicity and tolerance in plants and animals
Karlsruhe Institute of Technology
2023
University of California, Berkeley
2023
Ben-Gurion University of the Negev
2023
Florida International University
2023
United States Geological Survey
2023
University of Alabama
2023
University of Washington Applied Physics Laboratory
2022
University of Bologna
2022
University of Minnesota
2000-2021
Ames Research Center
2012-2021
Hematopoietic stem-cell transplantation (HSCT) is a potentially lifesaving therapy for several blood cancers and other diseases. For patients without suitable related HLA-matched donor, unrelated-donor registries of adult volunteers banked umbilical cord-blood units, such as the Be Match Registry operated by National Marrow Donor Program (NMDP), provide potential sources donors. Our goal in present study was to measure likelihood finding donor U.S. registry.Using human HLA data from NMDP...
Abstract Worldwide more than 400 plant species are now known that hyperaccumulate various trace metals (Cd, Co, Cu, Mn, Ni, and Zn), metalloids (As) nonmetals (Se) in their shoots. Of these, almost one-quarter Brassicaceae family members, including numerous Thlaspi Ni up to 3% of there shoot dry weight. We observed concentrations glutathione, Cys, O-acetyl-l-serine (OAS), tissue, strongly correlated with the ability hyperaccumulators collected from serpentine soils, goesingense, T. oxyceras,...
We have calculated six-locus high resolution HLA A∼C∼B∼DRB3/4/5∼DRB1∼DQB1 haplotype frequencies using all Be The Match® Registry volunteer donors typed by DNA methods at recruitment. Mixed typing data was inputted to a modified expectation–maximization (EM) algorithm in the form of genotype lists generated interpretation primary genomic IMGT/HLA v3.4.0 allele list. full cohort consists 6.59 million subjects categorized broad race level. Overall 25.8% individuals were C locus, and 5.2% DQB1...
Abstract Astragalus bisulcatus and Stanleya pinnata hyperaccumulate selenium (Se) up to 1% of plant dry weight. In the field, Se was mostly present in young leaves reproductive tissues both hyperaccumulators. Microfocused scanning x-ray fluorescence mapping revealed that hyperaccumulated trichomes A. bisulcatus. None 10 other elements tested were accumulated trichomes. Micro absorption spectroscopy liquid chromatography-mass spectrometry showed organic forms methylselenocysteine (MeSeCys;...
Abstract Progress is being made in understanding the biochemical and molecular basis of nickel (Ni)/zinc (Zn) hyperaccumulation Thlaspi; however, signaling pathways that control these mechanisms are not understood. We observed elevated concentrations salicylic acid (SA), a molecule known to be involved induced pathogen defense responses plants, strong predictor Ni six diverse Thlaspi species investigated, including hyperaccumulators goesingense, rosulare, oxyceras, caerulescens...
The molecular mechanisms responsible for selenium (Se) tolerance and hyperaccumulation were studied in the Se hyperaccumulator Stanleya pinnata (Brassicaceae) by comparing it with related secondary accumulator albescens using a combination of physiological, structural, genomic, biochemical approaches. S. accumulated 3.6-fold more was tolerant to 20 μ m selenate, while suffered reduced growth, chlorosis necrosis, impaired photosynthesis, high levels reactive oxygen species. Levels ascorbic...
• Some plants hyperaccumulate selenium (Se) up to 1% of dry weight. This study was performed obtain insight into whole-plant Se fluxes in hyperaccumulators. Selenium hyperaccumulators Astragalus bisulcatus and Stanleya pinnata were monitored over two growing seasons for seasonal fluctuations concentrations the chemically similar element sulfur (S). The related nonhyperaccumulators sericoleucus, Oxytropis sericea Thlaspi montanum included comparison. In both leaf decreased from April October,...
Abstract Selenium (Se) is an essential element for many organisms, but excess Se toxic. To better understand plant toxicity and resistance mechanisms, we compared the physiological molecular responses of two Arabidopsis (Arabidopsis thaliana) accessions, Columbia (Col)-0 Wassilewskija (Ws)-2, to selenite treatment. Measurement root length tolerance index demonstrated a clear difference between selenite-resistant Col-0 selenite-sensitive Ws-2. Macroarray analysis showed more pronounced...
• Selenium (Se) hyperaccumulation has a profound effect on plant–arthropod interactions. Here, we investigated floral Se distribution and speciation in flowers the effects of pollen quality plant–pollinator Floral were compared Stanleya pinnata, an hyperaccumulator, Brassica juncea, comparable nonhyperaccumulator. Pollen germination was measured from plants grown with varying concentrations visitation between high low Se. pinnata preferentially allocated to flowers, as nontoxic...
Trichloroethylene (TCE) is a widespread environmental pollutant common in groundwater plumes associated with industrial manufacturing areas. We had previously isolated and characterized natural bacterial endophyte, Enterobacter sp. strain PDN3, of poplar trees, that rapidly metabolizes TCE, releasing chloride ion. now report findings from successful three-year field trial endophyte-assisted phytoremediation on the Middlefield-Ellis-Whisman Superfund Study Area TCE plume Silicon Valley...
• To investigate whether selenium (Se) accumulation in plants provides a chemical defense against generalist insect herbivores, the feeding preference and performance of mix orthopteran species were investigated. The hyperaccumulator Stanleya pinnata accumulator Brassica juncea used herbivory studies laboratory, S. was also manipulative field experiment. In laboratory studies, both crickets grasshoppers avoided pretreated with selenate, while those given no choice died after eating leaves...
Hyperaccumulation, the rare capacity of certain plant species to accumulate toxic trace elements levels several orders magnitude higher than other growing on same site, is thought be an elemental defense mechanism against herbivores and pathogens. Previous research has shown that selenium (Se) hyperaccumulation protects plants from a variety Selenium hyperaccumulating sequester Se in discrete locations leaf periphery, making them potentially more susceptible some herbivore feeding modes...
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We report on the second phase of a programme to select relative Arabidopsis thaliana for use in large-scale molecular genetic studies nickel (Ni) and zinc (Zn) hyperaccumulation. also relatedness among Thlaspi caerulescens accessions utility using O-acetyl-L-serine as marker Ni Zn hyperaccumulation potential. Twenty-seven new metal-accumulating species collected Czech Republic, France, Greece, Italy, Slovenia USA during Spring-Summer 2002 were evaluated. The criteria established selection...
The organ-specific accumulation, spatial distribution, and chemical speciation of selenium (Se) were previously unknown for any species cactus. We investigated Se in Opuntia ficus-indica using inductively coupled plasma mass spectrometry, microfocused x-ray fluorescence elemental mapping (μXRF), K-edge absorption near-edge structure (XANES) spectroscopy, liquid chromatography-mass spectrometry (LC-MS). μXRF showed concentrated inside small conic, vestigial leaves (cladode tips), the cladode...
Abstract The goal of this study was to investigate how plant selenium (Se) hyperaccumulation may affect ecological interactions and whether associated partners Se hyperaccumulation. hyperaccumulator Astragalus bisulcatus collected in its natural seleniferous habitat, x-ray fluorescence mapping absorption near-edge structure spectroscopy were used characterize distribution speciation all organs as well encountered microbial symbionts herbivores. present at high levels (704–4,661 mg kg−1 dry...
Abstract Genetic matching for loci in the human leukocyte antigen ( HLA ) region between a donor and patient hematopoietic stem cell transplantation HSCT is critical to outcome; however, methods genotyping of donors unrelated registries often yield results with allelic phase ambiguity and/or do not query all clinically relevant loci. We present evaluate statistical method silico imputation alleles haplotypes large ambiguous population data from Be The Match ® Registry. Our builds on...