A5000157714- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Hip disorders and treatments
- Neurogenetic and Muscular Disorders Research
- Nerve Injury and Rehabilitation
- Foot and Ankle Surgery
- Stroke Rehabilitation and Recovery
- Diabetic Foot Ulcer Assessment and Management
- Balance, Gait, and Falls Prevention
- Orthopaedic implants and arthroplasty
- Shoulder Injury and Treatment
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Infant Development and Preterm Care
- Shoulder and Clavicle Injuries
- Lower Extremity Biomechanics and Pathologies
- Total Knee Arthroplasty Outcomes
- Musculoskeletal pain and rehabilitation
- Hip and Femur Fractures
- Family and Disability Support Research
- Hereditary Neurological Disorders
- Mesenchymal stem cell research
- Tendon Structure and Treatment
- Osteoarthritis Treatment and Mechanisms
- Prosthetics and Rehabilitation Robotics
University Children's Hospital Zurich
2018-2025
University of Zurich
2020-2025
Universitätsklinik Balgrist
2020-2024
Heidelberg University
2012-2022
University Hospital Heidelberg
2012-2022
University Hospital of Basel
2022
University of Basel
2022
Orthopädische Universitätsklinik
2011-2018
Behandlungszentrum Aschau
2017
Chirurgische Universitätsklinik Heidelberg
2013-2015
Hamstring lengthening commonly is performed for the treatment of flexed knee gait in patients with spastic diplegic cerebral palsy. Satisfactory short-term results after hamstring have been demonstrated various studies. However, evidence effectiveness to correct scant because small and inhomogeneous case series, different surgical techniques, short follow-up.The long-term thirty-nine diplegia who were managed intramuscular as a part multilevel surgery are presented. Standardized...
Background: Equinus of the foot at ankle is one most common deformities in patients with spastic diplegic cerebral palsy, leading to gait disturbances and secondary deformities. During single-event multilevel surgery, equinus commonly corrected by calf muscle lengthening, such as gastrocnemius-soleus intramuscular aponeurotic recession. Various studies have described satisfactory short-term results after However, there no evidence for maintenance correction because small heterogeneous case...
Abstract Background Bone marrow-derived mesenchymal stromal cells (BM-MSCs) play an important role in modern tissue engineering, while distinct variations of culture media compositions and supplements have been reported. Because MSCs are heterogeneous regarding their regenerative potential surface markers, these parameters were compared four widely used compositions. Methods isolated from bone marrow expanded established cell media. MSC yield/1000 MNCs, passage time growth index observed. In...
Aim We investigated the long‐term efficacy and safety of multilevel surgery ( MLS ) in ambulatory children with bilateral spastic cerebral palsy (CP). Method Two hundred thirty‐one were evaluated at short term (1.1y, SD 0.4) long (9.1y, 3.0) follow‐up using clinical examination gait analysis. was by studying changes Gait Profile Score GPS referenced to minimally important difference. Results Ambulatory aged 10 years 7 months 2y 11mo) Gross Motor Function Classification System levels I (19),...
The foot drop component of cavovarus deformity in patients with Charcot-Marie-Tooth disease is commonly treated by tendon transfer to provide substitute dorsiflexion or tenodesis prevent the from dropping. Our goals were use three-dimensional analysis evaluate outcome tibialis posterior dorsum and investigate whether works as an active substitution a tenodesis.We prospectively studied fourteen whom twenty-three feet correct part correction procedure. Five underwent unilateral treatment nine...
To validate the Clinical Frailty Scale (CFS) for prediction of 1-year all-cause mortality in emergency department (ED) and compare its performance to Emergency Severity Index (ESI).
Background: The evidence for distal rectus femoris transfer as a part of multilevel surgery the correction stiff-knee gait in children with spastic diplegic cerebral palsy is limited because inconsistent outcomes reported various studies and lack long-term evaluations. Methods: This study investigated results (mean, nine years) fifty-three ambulatory patients treated standardized surgery. Standardized three-dimensional analysis clinical examination were carried out before at one year years...
Abstract Objectives Although clinical applications using mesenchymal stromal cells ( MSC s) are becoming more frequent, procedures for their in vitro culture far from standardized. Growth factors such as FGF ‐2 frequently added during expansion to improve population growth and differentiation characteristics. However, up now its influence on surface marker distribution of s has been close unknown. The purpose this study was therefore analyse effects supplementation pre‐selection...
Equinus is the most common deformity in cerebral palsy (CP) and gastrocsoleus lengthening (GSL) commonly performed surgery to improve gait function ambulatory children with CP. Substantial variation exists indications for GSL surgical technique. The purpose of this study was review anatomy biomechanics utilize expert orthopaedic opinion through a Delphi technique establish consensus CP.A 17-member panel, Fellowship-trained paediatric surgeons, each at least 9 years clinical post-training...
The purpose of this study was to develop consensus for the surgical indications anterior distal femur hemiepiphysiodesis in children with cerebral palsy using expert surgeon opinion through a modified Delphi technique.The panel used 5-level Likert-type scale record agreement or disagreement 27 statements regarding hemiepiphysiodesis. Consensus defined as at least 80% responses being highest lowest 2 ratings. General 60%-79% falling into ratings.For hemiepiphysiodesis, were surveyed: general...