A5031528175- Ultrasound and Hyperthermia Applications
- Photoacoustic and Ultrasonic Imaging
- Advanced MRI Techniques and Applications
- Aortic aneurysm repair treatments
- Genetics, Aging, and Longevity in Model Organisms
- Advanced X-ray and CT Imaging
- Genetics, Bioinformatics, and Biomedical Research
- Ultrasound Imaging and Elastography
- Vascular Procedures and Complications
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Biomedical Text Mining and Ontologies
- Reservoir Engineering and Simulation Methods
- Gene expression and cancer classification
- Ultrasonics and Acoustic Wave Propagation
- Liver Disease Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Industrial Vision Systems and Defect Detection
- Dental Radiography and Imaging
- Chromosomal and Genetic Variations
- Genomics and Rare Diseases
- AI in cancer detection
- Advanced X-ray Imaging Techniques
- Circadian rhythm and melatonin
- Medical Image Segmentation Techniques
Vicomtech
2012-2022
Sener (Spain)
2021
Biogipuzkoa Health Research Institute
2016-2018
eHealth Africa
2014
Université de Bordeaux
2007-2011
Centre National de la Recherche Scientifique
2007-2010
Philips (Finland)
2010
Institut Polytechnique de Bordeaux
2007
Laboratoire Bordelais de Recherche en Informatique
2007
Abstract MR thermometry offers the possibility to precisely guide high‐intensity focused ultrasound (HIFU) for noninvasive treatment of kidney and liver tumours. The objectives this study were demonstrate therapy guidance by motion‐compensated, rapid volumetric temperature monitoring evaluate feasibility MR‐guided HIFU ablation in these organs. Fourteen sonications performed five pigs under general anaesthesia using an MR‐compatible Philips platform prototype. sonication power duration...
Fractal geometry measures the morphology of brain and detects CNS damage. We aimed to assess longitudinal changes on brain's fractal its predictive value for disease worsening in patients with Multiple Sclerosis (MS). prospectively analyzed 146 consecutive relapsing-remitting MS up 5 years clinical MRI (3 T) assessments. The dimension lacunarity were calculated regions using box-counting methods. Longitudinal mixed-effect models risk disability accumulation assessed Cox Proportional Hazard...
Thermotherapies can now be guided in real-time using magnetic resonance imaging (MRI). This technique is rapidly gaining importance interventional therapies for abdominal organs such as liver and kidney. An accurate online estimation characterization of organ displacement mandatory to prevent misregistration correct motion related thermometry artifacts. In addition, when the ablation performed with an extracorporal heating device high intensity focused ultrasound (HIFU), continuous basis...
Abstract MR‐thermometry allows monitoring of the local temperature evolution during minimally invasive interventional therapies. However, for particular case in human breast, magnetic field variations induced by respiratory cycle lead to phase fluctuations requiring a suitable correction strategy prevent thermometry errors. For this purpose look‐up‐table‐based multibaseline approach as well model‐based algorithm were applied correct periodic changes. The proposed method is compatible with...
MR‐guided high intensity focused ultrasound (HIFU) has evolved into a promising non‐invasive technique for the ablation of pathological tissue in abdominal organs. However, since perfusion rates these organs lead to effective cooling, sustained sonications 30–90 s are required achieve sufficiently temperature elevation induce necrosis. This is complicated by constant displacement target due respiratory cycle. study proposes sub‐second 3D HIFU‐beam steering under MR‐guidance near real‐time...
Real-time magnetic resonance (MR) thermometry provides continuous temperature mapping inside the human body and is therefore a promising tool to monitor control interventional therapies based on thermal ablation. Temperature information must be mapped reference position of observed organs in order allow dose computation, as history required for each pixel. Motion compensated MR-thermometry thermotherapy has cope with radio-frequency (RF) artifacts relaxation-time changes monitored tissue....
Biological neural systems are powerful, robust and highly adaptive computational entities that outperformconventional computers in almost all aspects of sensory-motor integration. Despite dramatic progress ininformation technology, there is a big performance discrepancy between artificial systemsand brains seemingly simple orientation navigation tasks. In fact, no system exists can faithfullyreproduce the rich behavioural repertoire tiny worm Caenorhabditis elegans which features one...
In this work, a method for the optimization of volumetric MR‐guided high intensity focused ultrasound (HIFU) ablations is presented. We propose to monitor thermal dose in target area ensure complete destruction tumor tissue. A trajectory ablation points optimized based on energy distribution measured by PRFS‐based MR thermometry. The combination with 3D motion correction technique including tracking focal point position allows an effective tissue minimal energy, time and damage outside area....
This study compares several state-of-the-art regularization methods applicable to aortic aneurysm segmentation likelihood maps provided by a Deep Convolutional Neural Network (DCNN). These algorithms vary from simple Otsu's thresholding and K-Means clustering, more complex Level-sets Conditional Random Fields. Experiments demonstrate that K-means yields the best results for current application, which poses question about need employ sophisticated approach post-processing output probability maps.
Magnetic resonance (MR) systems can be used to monitor temperature changes in and around a treated region during an hyperthermic ablation procedure. Dynamic monitoring allows on-line prediction of cellular destruction the intervention. MRI associate each volume unit with complex number. Phase component is 2pi periodic (it function wrapped phase) accounts for noise sources present MR imaging. Robust spatial phase unwrapping necessary prerequisite several applications. This study proposes...
Considering the growing interest towards next generation sequencing (NGS) and data analysis, substantial challenges associated to fully exploiting these technologies without proper experience, an expert knowledge-based user-friendly analytical tool was developed allow non-bioinformatics experts process NGS genomic data, automatically prioritise variants make their own annotations. This using a user-centred methodology, where iterative followed until useful product developed. allows users...