A5044870516- Bariatric Surgery and Outcomes
- Body Contouring and Surgery
- Esophageal and GI Pathology
- Gastrointestinal motility and disorders
- Minimally Invasive Surgical Techniques
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Tracheal and airway disorders
- Ion Channels and Receptors
- Diet and metabolism studies
- Dysphagia Assessment and Management
- Cardiovascular Disease and Adiposity
- Breast Cancer Treatment Studies
- Drug Transport and Resistance Mechanisms
- Biochemical Analysis and Sensing Techniques
- Obstructive Sleep Apnea Research
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Intestinal and Peritoneal Adhesions
- Foreign Body Medical Cases
- Trauma Management and Diagnosis
- Breast Implant and Reconstruction
- Lung Cancer Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Hernia repair and management
Homerton University Hospital
2006-2019
EES Research (United Kingdom)
2013
Sunderland Royal Hospital
2013
City Hospital
2013
University Hospitals Bristol NHS Foundation Trust
2013
Homerton University Hospital NHS Foundation Trust
2010
Hammersmith Hospital
2006
Royal London Hospital
1995
Lister Hospital
1992-1994
Abstract Background Progress in identifying safer, effective drugs to increase gastric emptying is impeded by failed clinical trials. One potential reason for failure lack of translation from animal models the human condition. To make progress, actions existing and new therapeutic candidates need be understood isolated stomach. Methods Neuromuscular activities were evoked antrum circular muscle electrical field stimulation ( EFS ), defined phenotypically using pharmacological tools. Key...
Abstract Subcutaneous mastectomy and axillary dissection combined with immediate reconstruction was used to treat primary breast cancer in a consecutive series of 111 patients. Local recurrence occurred 19 patients (17 per cent) during mean, follow-up 30 (range 6–60) months. Complete control local disease achieved all except one, who had terminal disease. Prophylactic radiotherapy avoided for 83 cent patients, good cosmetic results were obtained 89 cent. These support the use this technique...
The aim was to characterise RQ-00201894, a novel non-macrolide motilin agonist, using human recombinant receptors and then investigate its ability facilitate cholinergic activity in stomach. A reporter gene assay assessed receptor function. Selectivity of action determined panel different receptors, ion channels, transporters enzymes. Cholinergically-mediated muscle contractions were evoked by electrical field stimulation (EFS) gastric antrum. results showed that erythromycin acted as full...
See also: Commentaire de travail A. Fritscher-Ravens et al., pp. 29Endoscopy 2009; 41(01): 95-96DOI: 10.1055/s-0032-1306724
The complications of open antireflux operations may be reduced by laparoscopic techniques. Fifteen patients median age 42 (range 16-79) years with gastro-oesophageal reflux underwent fundoplication. Preoperative and postoperative assessment was clinical scoring, oesophageal pH measurement manometry. Median (range) operating time 115 (60-210) min hospital stay 3 (1-6) days, no conversions to operation only one minor wound infection. Four had occasional symptoms on at a 7 weeks nine dysphagia....
<b>Background and study aims:</b> In cases where biopsies remain inconclusive, removal of mediastinal lymph nodes for further analysis requires surgical means. Natural orifice transluminal endoscopic surgery (NOTES) procedures allow incision/closure the gut wall, which might enable excision pre-marked nodes. The aims current were to investigate feasibility, safety, reproducibility node generation in an animal model ultrasound-guided (EUS) (ELR) using transesophageal NOTES access/closure...
To determine the expression of bile acid receptor, farnesoid X (FXR), in human gastric mucosa and investigate correlations between body-mass index (BMI) patients with obesity, changes weight BMI following vertical sleeve gastrectomy (VSG).Human was obtained from normal/overweight individuals (macroscopically-normal tissue surgery for malignancy) or obesity (VSG). The FXR its isoforms (FXRα, FXRβ) were examined by quantitative PCR compared G protein-coupled GPBA. In loss determined VSG.FXRα...
Introduction: Full thickness biopsy (FTB) of the gut is necessary for diagnosis enteric neuromuscular diseases (ENMD). To date FTB only done by surgery. Endoscopic methods would enable easier ENMD and facilitate research other diseases.
<h3>Introduction</h3> The obesity epidemic has seen a corresponding rise in bariatric surgery, resulting an increased prevalence of patients with post-operative complications from surgery. Endoscopists need to be aware the symptoms and common findings at endoscopy, various endoscopic treatments available. <h3>Method</h3> A total 150 out 1947 (7.7%) who underwent surgery for were referred Endoscopy service between March 2011 July 2014. We retrospectively reviewed patient characteristics, type...
<h3>Background</h3> Obstructive Sleep Apnoea (OSA) is prevalent in obese patients and has substantial impact on health society<sup>1</sup>. We undertook this analysis to examine changes severity by studying the Apnoea-Hypopnoea Index (AHI) pre post bariatric surgery a London District General Hospital. <h3>Methods</h3> retrospectively reviewed with history of OSA who underwent laparoscopic procedure between 2011 2012, preceded sleep study. Repeat studies were performed those reported...
Background: NICE clinical guideline for obesity (CG43), 2006 is the benchmark provision of services primary care trusts (PCTs) in England.There a wide variation availability bariatric procedures on NHS.There growing perception that criteria funding surgery have become more stringent recently.The aims this study were to review PCTs England last three financial years, 2009-10, 2010-2011 and 2011-2012.Methods: We sent out questionnaires electronically all 147 asking about their requested number...
Dimarakis, Ioannis N. MRCS; Taribagil, Sanjay FRCS; Mannur, Kesava R. FRCS Author Information