A5003876221- Pharmaceutical Practices and Patient Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Pharmacological Effects and Toxicity Studies
- Bipolar Disorder and Treatment
- Mycobacterium research and diagnosis
- Schizophrenia research and treatment
- Cardiac Arrest and Resuscitation
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Social Media in Health Education
- Intensive Care Unit Cognitive Disorders
- Pharmaceutical studies and practices
- Tuberculosis Research and Epidemiology
- Anesthesia and Sedative Agents
- Sepsis Diagnosis and Treatment
- Patient Safety and Medication Errors
- Antibiotic Use and Resistance
- Blood Pressure and Hypertension Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pharmacological Effects of Natural Compounds
- Medication Adherence and Compliance
- Neurosurgical Procedures and Complications
- Antibiotics Pharmacokinetics and Efficacy
Massachusetts General Hospital
2021-2025
Monash University
2024
Mayo Clinic
2020-2023
Oregon Health & Science University
2020-2023
University of Rhode Island
2022
WinnMed
2022
Mayo Clinic in Florida
2020
Mayo Clinic in Arizona
2020
Queen Mary University of London
2010
The University of Texas Southwestern Medical Center
1996-2003
Objective: Case series and follow-up studies suggest that clozapine may have mood-stabilizing properties in addition to antipsychotic action patients with schizoaffective disorder, bipolar type, I but the generalizability of these findings is limited. This article describes a randomized, open study add-on therapy versus treatment as usual for treatment-resistant illness history mania. Method: Thirty-eight meeting DSM-IV criteria or disorder was deemed were randomly assigned (N=19) (no...
Abstract Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for Mycobacterium abscessus. The majority infections pulmonary origin (7/12; 58.3%). median (interquartile range) duration OMC was 6.2 (4.2–11.0) months. Clinical success occurred in 9/12 (75.0%) patients. Three experienced possible adverse effect while on therapy.
Infections due to nontuberculous mycobacteria (NTM) continue increase in prevalence, leading problematic clinical outcomes. Omadacycline (OMC) is an aminomethylcycline antibiotic with FDA orphan drug and fast-track designations for pulmonary NTM infections, including
Uncontrolled hypertension is a risk factor of heart attack, stroke, dementia, and other conditions. In outpatients with hypertension, blood pressure (BP) may be controlled at only 30%-50% visits depending on the population studied. Hospital admission ideal for achieving guideline-directed BP targets, given resource-intensive environment. We evaluated relationship between control performance during neurocritical care hospital rates uncontrolled discharge over subsequent 2 years. This...
Abstract Purpose Numerous clinical scoring tools exist for a variety of patient populations and disease states, but few provide information specifically designed use by critical care pharmacists. The medication regimen complexity–intensive unit (MRC-ICU) score was to high-level about the complexity critically ill patients’ regimens To date, implementation this in electronic medical record (EMR) has not been reported. Summary Using an agile project management framework, MRC-ICU rapidly...
Antibiotic-resistant Gram-negative bacteria have been associated with substantial morbidity and mortality limited treatment options available. Omadacycline (OMC) is an aminomethylcycline antibiotic that has shown to exhibit broad in vitro activity against antibiotic-resistant bacteria. Given the lack of real-world data, primary objective our report was describe early experience OMC for resistant infections. This a real-world, multicenter, observational cases series/pilot study conducted USA....
Objectives: Research has demonstrated that beliefs or expectancies can exert a powerful influence on treatment and/or drug effects. As patients participate in more complementary alternative treatments for psychiatric conditions, it is important to assess the role of belief expectancy response nontraditional approaches. The Acupuncture Beliefs Scale was developed efficacy acupuncture both physical and symptoms conditions. Development psychometric properties scale are described. Design...
Introduction Bromocriptine is a dopamine receptor agonist used for central hyperthermia with limited data. We describe our single-center experience utilizing bromocriptine hyperthermia, including the population treated, most common dosing regimens, adverse events, and discontinuation reasons.
Abstract Background and Objectives Valproate has wide pharmacokinetic variability a narrow therapeutic index. Its protein binding is unpredictable, particularly among critically ill patients who may experience unexpectedly elevated free concentrations. We sought to identify the clinical consequences determinants of occult valproate toxicity in adults. Methods conducted multicenter retrospective cohort study adult admitted an intensive care unit (ICU) were receiving had concurrent total...
Abstract Objective Intravenous (IV) push (IVP) is an alternative administration method for levetiracetam, but evidence evaluating it compared to IV piggyback (IVPB) loading doses in acutely seizing patients limited, particularly with status epilepticus (SE). This study aimed compare the efficiency and safety of IVP versus IVPB levetiracetam doses. Methods was a single‐center sequential retrospective conducted adult (≥18 years) who received dose (>2000 mg or ≥20 mg/kg) acute suspected...
Nuclear magnetic resonance instruments are becoming available to the do-it-yourself community. The challenges encountered in endeavor build a imaging instrument from scratch were confronted four-day hackathon at Singapore University of Technology and Design spring 2024. One day was devoted educational lectures three days system construction testing. Seventy young researchers all parts world formed six teams focusing on magnet, gradient coil, RF console, integration, design, which together...
Current Brain Injury Guidelines (BIG) characterize patients with intracranial hemorrhage taking antiplatelet or anticoagulant agents as BIG 3 (the most severe category) regardless of trauma severity. This study assessed the risk in-hospital mortality need for neurosurgery in low-dose aspirin who otherwise would be classified 1.This was a retrospective at an academic level 1 center. Patients were included if they admitted traumatic intracerebral and evaluated by criteria. Exclusion criteria...
Information represented through conventional text may fall short of capturing the attention and promoting engagement with today's digital audience. Transforming into visual tools, such as infographics, has emerged a simplified method delivering information to attract broader audience enhance dissemination. The first step evaluate potential value infographics is quantify their appeal rates over text. This retrospective pilot analysis sought difference between for tweets containing an...