A5044644994- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Hormonal and reproductive studies
- Psychedelics and Drug Studies
- Hypothalamic control of reproductive hormones
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Ovarian function and disorders
- Fluorine in Organic Chemistry
- Chemical Synthesis and Reactions
- Neuropeptides and Animal Physiology
- Oxidative Organic Chemistry Reactions
- Alzheimer's disease research and treatments
- Receptor Mechanisms and Signaling
Louisiana State University Health Sciences Center New Orleans
2024
The University of Texas at Austin
2023
Southwestern University
2021
Cocaine predictive cues and contexts exert powerful control over behaviour can incite cocaine seeking taking. This type of conditioned is encoded within striatal circuits, these circuits behaviours are, in part, regulated by opioid peptides receptors expressed medium spiny neurons. We previously showed that augmenting levels the peptide enkephalin striatum facilitates acquisition place preference (CPP), while receptor antagonists attenuate expression CPP. However, whether necessary for CPP...
1,4-Diketones have been synthesized via a reductive homocoupling of α-haloketones. Addition Grignard reagent to titanium(IV) isopropoxide affords low-valent titanium(III) intermediate that is believed mediate radical dimerization reaction. The reaction works well for variety aromatic α-haloketones including heteroaromatic compounds.
Abnormal accumulation of Tau protein in the brain disrupts normal cellular function and leads to neuronal death linked with many neurodegenerative disorders such as Alzheimer's disease. An attractive approach mitigate Tau-induced neurodegeneration is enhance clearance toxic aggregates. We previously showed that upregulation fly gene
Abstract Drug predictive cues and contexts exert powerful control over behavior can incite drug seeking taking. This association the behavioral output are encoded within striatal circuits, regulation of these circuits by G-protein coupled receptors affects cocaine-related behaviors. Here, we investigated how opioid peptides expressed in medium spiny neurons (MSNs) regulate conditioned cocaine seeking. Augmenting levels peptide enkephalin striatum facilitates acquisition place preference...