Noninvasive methods for monitoring diabetes are being developed to eliminate the need invasive finger-prick testing. Here, we propose noninvasive detection of tear glucose using contact lenses that contain cerium oxide nanoparticles (CNPs). We chemically conjugated CNPs with oxidase (GOx) poly(ethylene glycol) (PEG) (CNP-PEG-GOx). GOx oxidizes into hydrogen peroxide, which rapidly (∼1 min) reduces colorless Ce3+ yellow Ce4+ high sensitivity (>0.1 mM). Then, CNP-PEG-GOx can be analyzed...

Abstract Aim of this study is to evaluate the differences in corneal endothelial cell morphology and thickness patients with without type 2 diabetes related age, disease duration, HbA1c percentage. This retrospective cross-sectional included 511 (1022 eyes) 900 (1799 non-diabetic patients. The density (ECD), variation size (CV), percentage hexagonal cells, central (CCT) were analyzed using a noncontact specular microscope Pentacam Scheimpflug camera. We also examined correlation between...

A pterygium is a common conjunctival degeneration and inflammatory condition. It grows onto the corneal surface or limbus, causing blurred vision cosmetic issues. Ultraviolet well-known risk factor for development of pterygium, although its pathogenesis remains unclear, with only limited understanding hereditary basis. In this study, we collected RNA-seq from both pterygial tissues (as controls) six patients (a total twelve biological samples) retrieved publicly available data, including...

Myopia is the most common ocular disorder and mainly caused by axial elongation of sclera. If stiffness sclera increased, it can inhibit myopia progression. The aim this study to compare effect collagen crosslinking with different types concentrations carbohydrates on chemical bond ultrastructural change rabbit sclera.Nine New Zealand white rabbits were treated five, sequential sub-Tenon injections 0.15 mL solutions ribose, sucrose, glycogen 0.1, 0.2 0.4 M concentration at right eye over 14...

The aim of this study is to compare the endothelial cell density (ECD) and morphology between diabetic mellitus (DM) nondiabetic patients at 1 year after phacoemulsification in operated eyes nonoperated eyes.Evaluation was performed 28 (56 eyes) with type 2 diabetes 37 (74 without who underwent 1-year interval cataract surgery. Using a noncontact specular microscope Scheimpflug rotating camera, corneal parameters were analyzed before Subgroups analysis based on disease duration 10 years...

At present, we are moving into the era of Internet Things. In this new era, it will be easy to find access points (APs) wherever go. Signals from these APs can used for more than just connecting Internet. The presence a human between two and human's behavior cause change in waveform Wi-Fi signal. paper, explain how changes waveforms affect channel state information signal machine learning utilize that recognize predict behavior.

Increasing interest in microincision cataract surgery has led to the use of more flexible intraocular lens (IOL). Flexible IOL may cause deformation and refractive error when capsule contraction syndrome (CCS) occurred. In this retrospective observational case series study, aim was report four cases hyperopic shift caused by CCS after phacoemulsification with foldable implantation. All patients underwent in-the-bag implantation an Akreos MI60 (Bausch Lomb) from 2010 2016 our clinic. These...

Rationale: Functional visual loss (FVL) can manifest as various symptoms. Decreased distant acuity is the most common symptom and field defect second symptom. Hemianopsia rarely reported. In an atypical situation of FVL, it important to prove that no organic pathology exists, through detailed history taking appropriate examinations. Patient concerns: This review presents case a 48-year-old male patient presented with decreased bilateral after traffic accident 3 weeks ago. Visual test showed...

In this study, we investigated the lipolytic effects of an Emblica officinalis (Indian gooseberry [IG]) and Hordeum vulgare L. (barley sprout [BP]) mixture on differentiated 3T3-L1 cells. On ninth day differentiation, Oil red O staining Western blotting were performed; additionally, glycerol release triglyceride (TG), fatty acid (FA), cyclic adenosine monophosphate (cAMP) levels measured. Compared to differentiation-induced control (C) group, IG BP inhibited intracellular TG FA by 61.7%...

Rationale: Terrien's marginal corneal degeneration (TMD) is characterized by progressive peripheral thinning. It appears primarily above the age of 40 years and rare at younger ages. Spontaneous perforation in TMD a rare, but serious complication that may occur childhood. Patient concerns: This review presents case 16-year-old girl presented with blurred vision right eye on awakening morning. Slit-lamp examination revealed superior thinning perforation. Diagnoses: The best-corrected visual...

To assess the early structural changes at clear corneal cataract incision sites and surgical outcomes using anterior segment optical coherence tomography (AS-OCT).We evaluated 80 eyes of 59 patients who underwent phacoemulsification with a incision. All incisions were 1wk, 1, 3mo postoperatively AS-OCT analyzed regarding angle, length incision, maximal thickness if present, endothelial gap area. The divided into two groups according to whether or not an was present 1wk (endothelial gap,...

PURPOSE: To compare the effects of distance from inner and outer corneal incision wounds to apex on changes in astigmatism after cataract surgery. METHODS: Seventy-two eyes with anterior less than 2.50 diopters (D) were evaluated. The between wound was measured using Pentacam (Oculus Optikgeräte, Wetzlar, Germany) Scheimpflug image Image J program (National Institutes Health, Bethesda, MD). Patients subgrouped into close (less 4,816.44 µ m) far (4,816.44 m or greater) groups based median...

Although enzyme-linked immunosorbent assay (ELISA) technology has been widely accepted for binding assays against the polo-box domain (PBD) of polo-like kinase-1 (Plk1), these have a limitation-related heterogeneous procedure, such as multiple incubations and washing steps to apply high-throughput screenings (HTSs). In present study, Plk1-PBD based on time-resolved fluorescence energy transfer (TR-FRET) was developed HTS PBD-binding inhibitors. The TR-FRET-based is sensitive robust can be...

Abstract Rationale: One-and-a-half syndrome (OAAH) is characterized as the combination of ipsilateral horizontal gaze palsy and internuclear ophthalmoplegia. OAAH accompanied with 7th 8th cranial nerve called 16-and-a-half syndrome. We aimed to report case metastatic pons tumor. Patient concerns: A 57-year-old male diagnosed nonsmall-cell lung cancer (NSCLC) brain metastasis occurring 15 months ago was referred our clinic chief complaint diplopia right palsy. Diagnosis: According patient...

Background: The anatomy of pterygium consists the head, neck, and body. Prior studies have examined three parts collectively, yet treatment methods their success rates differ based on anatomical characteristics. In this study, we divide tissue into Main (head neck) Acc (body) to investigate its pathogenesis across regions. Purposes: This study aims understand identify potential therapeutic targets pterygium. Through a robust multi-omics analysis bulk single-cell RNA sequencing (RNA-seq) data...

Abstract Aim of this study is to evaluate the differences in corneal endothelial cell morphology and thickness patients with without type 2 diabetes related age, disease duration, HbA1c percentage. This retrospective cross-sectional included 511 (1022 eyes) 900 (1799 non-diabetic patients. The density (ECD), variation size (CV), percentage hexagonal cells, central (CCT) were analyzed using a noncontact specular microscope Pentacam Scheimpflug camera. We also examined correlation between...

Thygeson's superficial punctate keratitis (TSPK) is a recurrent bilateral corneal epithelial disease. Typically, small, multiple discrete lesions occur in the central cornea. However, dendritic are rare. Herein, we report rare case of TSPK both eyes after unilateral lesion. A 42-year-old woman presented with decreased vision and foreign body sensation her right eye that persisted for 1 month. Her uncorrected visual acuity best-corrected (BCVA) were 20/160 eye. Slit-lamp microscopy revealed...

Myopia is a substantial global public health concern primarily linked to the elongation of axial length eyeball. While numerous animal models have been employed investigate myopia, specific contributions genetic factors and intricate signaling pathways involved remain incompletely understood. In this study, we conducted RNA-seq analysis explore genes in two distinct myopia-inducing mouse models: form-deprivation myopia (FDM) lens-induced (LIM). Comparative with control group revealed...

Neuroretinitis is classically defined as a clinical triad of unilateral, painless vision loss, accompanied by optic disc edema and characteristic macular star formation. The causes neuroretinitis can be categorized infectious, non-infectious, idiopathic, therefore differential diagnosis careful evaluation are required, owing to the various etiologies masqueraders.A 54-year-old woman presented clinic with blurred in both eyes. A complete ophthalmic examination revealed margins exudates,...

Cataracts are a disease that is usually caused by aging and involve the irreversible degeneration of lens material. On other hand, transient cataracts have also been reported, mainly due to systemic hyperglycemia, which often occurs bilaterally. However, reports spontaneous regression unilaterally occurring in patients with normal blood glucose levels rare. Here, we report rare case unilateral posterior subcapsular an adult levels.A 42-year-old woman presented distorted vision her right eye....

Abstract Background Increasing interest in microincision cataract surgery has led to the use of more flexible intraocular lens (IOL). Flexible IOL may cause deformation and refractive error when capsule contraction syndrome (CCS) occurred. In this retrospective observational case series study, aim was report four cases hyperopic shift caused by CCS after phacoemulsification with foldable implantation. Case presentation All patients underwent in-the-bag implantation an Akreos MI60 (Bausch...