- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Reproductive System and Pregnancy
- Immunotherapy and Immune Responses
- Plant Physiology and Cultivation Studies
- Parathyroid Disorders and Treatments
- Plant Gene Expression Analysis
- Adrenal Hormones and Disorders
- Pituitary Gland Disorders and Treatments
- Agronomic Practices and Intercropping Systems
- Endometriosis Research and Treatment
- Forest ecology and management
- CAR-T cell therapy research
- Adrenal and Paraganglionic Tumors
- Gout, Hyperuricemia, Uric Acid
- Advanced Algebra and Logic
- Soil erosion and sediment transport
- Plant Disease Resistance and Genetics
- Fuzzy and Soft Set Theory
- IL-33, ST2, and ILC Pathways
- Soil Carbon and Nitrogen Dynamics
- Mycorrhizal Fungi and Plant Interactions
- Reproductive Physiology in Livestock
- Agroforestry and silvopastoral systems
- Diamond and Carbon-based Materials Research
Shanxi Agricultural University
2025
Ministry of Agriculture and Rural Affairs
2025
Chinese Academy of Forestry
2008-2024
State Forestry and Grassland Administration
2019-2023
Shenzhen Maternity and Child Healthcare Hospital
2023
Tianjin Medical University General Hospital
2007-2022
Paulownia Research Center
2008-2022
Central South University of Forestry and Technology
2022
Forestry Research Institute
2022
Nanyang Normal University
2021
A large, transient population of natural killer (NK) cells appears in the murine uterine mesometrial triangle during pregnancy. Depletion (u) NK cells, recently achieved using gene-ablated and transgenic mice, results pathology. Pregnancies from matings homozygous T cell-deficient tg epsilon 26 mice have <1% normal uNK cell frequency, no development an implantation site-associated metrial gland, edematous decidua with vascular pathology that includes abnormally high vessel walls/lumens...
The requirements for interleukin (IL)-12/signal transducer and activator of transcription (Stat)-4 signaling induction T cell-specific interferon (IFN)-gamma expression in the development helper cell (Th)1-type pathology were examined two different models experimental colitis. In each model, abnormal reconstitution compartment immunodeficient mice by adoptive transfer leads to a wasting syndrome inflammation colon, induced IFN-gamma tumor necrosis factor (TNF)-alpha-producing cells. We show...
Strategies of cell depletion were pursued to extend understanding the functions natural killer (NK) cell-like large granulated lymphocytes found in rodent uterus during pregnancy. Repeated infusions antibody Ly-49G2, a surface marker thought be expressed by progenitor forms these cells, removed Ly-49G2+ cells from virgin but not pregnant uterus. Large uterine also differentiated pregnancy transgenic mice that carried deletion IL-2 gene. This population was absent two strains mice,...
ABSTRACT T-cell development is under the tight control of thymic microenvironments. Conversely, integrity microenvironments depends on physical presence developing thymocytes, a phenomenon designated as ‘thymic crosstalk’. We now show, using three types immunodeficient mice, i.e. CD3ε transgenic RAGnull mice and RAGnull-bone-marrow-transplanted that point in lymphoid where triple negative (CD3−,CD4−,CD8−) thymocytes progress from CD44+CD25− towards CD44− CD25+, influences epithelial cells,...
Abstract An inflammatory bowel disease (IBD) comparable to human ulcerative colitis is induced upon transfer of T cell‐depleted wild‐type (F1) bone marrow into syngeneic cell‐deficient (tgε26) mice (F1 → tgε26). Previously we have shown that activated CD4 + cells predominate in transplanted tgε26 mice, and adoptive experiments verified the potential these cause immunodeficient recipient mice. Using flow cytometry for detection intracellular cytokine expression, demonstrate present study...
The development of plant-growth-promoting bacteria (PGPB) is one the important research topics in agricultural microbiology. Four bacterial isolates that exhibited nitrogen fixation, phosphate and potassium solubilization, as well indole-3-acetic acid (IAA) siderophore production abilities, were selected from biogas residue, namely BR-1, BR-16, BR-17, BR-44. According to morphological molecular biological identification, BR-44 belonged Bacillus subtilis, cereus, megaterium, respectively....
Abstract During thymocyte differentiation, the T cell receptor (TCR)‐β genes are rearranged before TCR‐α genes. Immature CD4 − 8 double‐negative thymocytes with a productive rearrangement of TCR‐β locus selected to continue maturation + double‐positive stage, driven by signals through pre‐TCR. The pre‐TCR can be synchronized injection mice anti‐CD3ϵ monoclonal antibody. Using this approach, we demonstrated coordinated induction triad responses in immature thymocytes: arrest V DJ locus,...
In this paper, we present the definition of fuzzy n-ellipsoid numbers that are a special kind n-dimensional which not only more objective and rational in expressing uncertain multichannel digital information than n-cell but keep convenience being used applications researches theory as well. We also obtain two representation results. Then, for sake application numbers, define some kinds investigate their properties, set up specific iterative algorithm membership function value, prove...
Objective To investigate the effects of Cushing’s disease (CD) and adrenal-dependent syndrome (ACS) on bone mineral density (BMD) metabolism. Methods Data were retrospectively collected for 55 patients with hypercortisolism (CD, n = 34; ACS 21) from January 1997 to June 2014. BMD was examined in all patients, turnover markers tested some patients. Healthy controls (n 18) also recruited. Results The lumbar spine femoral neck significantly lower CD groups than control group. Lumbar collagen...
NK cells are believed to play a critical role in the development of immunity against Leishmania major. We recently found that transplantation wild-type bone marrow into neonatal tgepsilon 26 mice, which deficient T and cells, resulted normal cell development, but no or poor development. Using this novel model we analyzed Th1 response control cutaneous L. major infection. Mice selectively lacking (NK-T+) developed an efficient Th1-like response, produced significant amounts IL-12 IFN-gamma,...
Background Nicotine dependence is a significant public health problem. This study attempted to characterize the prevalence and familial aggregation of nicotine in China.
Journal Article Over-expression of CD3ε transgenes blocks T lymphocyte development Get access Baoping Wang, Wang Search for other works by this author on: Oxford Academic PubMed Google Scholar Christiaan Levelt, Levelt 1Max-Planck-Institut fur ImmunbiologiePostfach, Freiburg, Germany Mariolina Salio, Salio Dexian Zheng, Zheng Jaime Sancho, Sancho Chih-Pin Liu, Liu Jian She, She Manley Huang, Huang 2GenPharm InternationalMountain View, CA 94043, USA Kay Higgins, Higgins USA3DeWitt Wallace...
Background Maternal polycystic ovary syndrome (PCOS) may increase the risk of attention-deficit/hyperactivity disorder (ADHD) in offspring; however, their association remains unexplored Asian populations. Hence, this study aimed to investigate between maternal PCOS and ADHD offspring aged 3–6 years whether it differed by sex. Methods This was a district-wide population-based 87,081 preschoolers from 234 kindergartens Longhua District, Shenzhen, China. The parents were invited complete...
Abstract NK cells have been shown to play a role in the modulation of B cell differentiation and Ab production. Using novel murine model deficiency, we analyzed vivo regulation Ag-specific After immunization with OVA or keyhole limpet hemocyanin CFA, cell-deficient (NK−T+) mice developed an efficient Th1 response produced significant levels IFN-γ but displayed markedly reduced absent IgG2a There were no differences IgG, IgG1, IgG2b between NK−T+ NK+T+ mice. Furthermore, cell-reconstituted,...
Abstract CD3γ, δ, ε, and ζ proteins together with the pre-TCR α-chain (pTα) a rearranged TCR β-chain assemble to form that controls double negative (DN) positive (DP) stages of thymopoiesis. The CD3 are expressed before pTα β-chains in prothymocytes intracellularly precursor NK cells, suggesting complex may function independent TCRβ. In this report, both role CD3ε exclusively, collectively, thymocyte cell development were examined. mouse strain termed εΔP, neomycin cassette inserted within...