A5085797215- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Colorectal Cancer Treatments and Studies
- Cancer Immunotherapy and Biomarkers
- Hematopoietic Stem Cell Transplantation
- Galectins and Cancer Biology
- T-cell and B-cell Immunology
- Circular RNAs in diseases
- Genetic factors in colorectal cancer
- MicroRNA in disease regulation
- Long-Term Effects of COVID-19
Nanchang University
2016-2025
First Affiliated Hospital of Nanchang University
2023-2025
First Affiliated Hospital of Jiangxi Medical College
2025
China-Japan Friendship Hospital
2023
Central South University
2021
Abstract Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4), an emerging immune checkpoint molecule, exhibits therapeutic potential in acute myeloid leukemia (AML). While single nucleotide polymorphisms (SNPs) of genes have been extensively investigated AML, the association between LILRB4 genetic and clinical outcomes remains unexplored. We SNPs within immunoglobulin domain immunoreceptor tyrosine-based inhibitory motif (ITIM) regions 151 AML patients 203 controls. The...
The engulfment and cell motility (ELMOs) family of proteins plays a crucial role in tumor migration invasion. However, the function ELMO3 is poorly defined. To elucidate its development progression colorectal cancer (CRC), we examined expression 45 cases paired CRC tissues adjacent normal tissues. Furthermore, assessed effect knockdown on proliferation, cycle, migration, invasion F-actin polymerization HCT116 cells. result shows that was significantly increased comparison to Moreover, this...
With the alarming surge in COVID-19 cases globally, vaccination must be prioritised to achieve herd immunity. Immune dysfunction is detected majority of patients with COVID-19; however, it remains unclear whether immune responses elicited by function against Omicron subvariant BA.2. Of 508 enrolled infected BA.2, 102 were unvaccinated controls, and 406 vaccinated. Despite presence clinical symptoms both groups, led a significant decline nausea or vomiting, abdominal pain, headache, pulmonary...
<title>Abstract</title> Colorectal cancer (CRC) is among the leading causes of cancer-related mortality globally. Metastatic colorectal (mCRC) with ultra-hypermutation uncommon and its underlying pathogenesis remains incompletely characterized. Additionally, response to immunotherapy in ultra-hypermutated mCRC not well defined. Here we report a unique case 33-year-old Chinese woman right-sided colon adenocarcinoma harboring somatic mutations POLE (p.A465V), MSH6 (p.G237*), MSH2 (p.T934M)...
ABSTRACT With the alarming surge in COVID-19 cases globally, vaccination must be prioritised to achieve herd immunity. Immune dysfunction is detected majority of patients with COVID-19; however, it remains unclear whether immune responses elicited by function against Omicron subvariant BA.2. Of 508 BA.2-infected enrolled, 102 were unvaccinated controls and 406 vaccinated. Despite presence clinical symptoms both groups, led a significant decline nausea or vomiting, abdominal pain, headache,...