Amy McCarthy

ORCID: 0000-0003-3456-0383
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About
Contact & Profiles
Research Areas
  • Monoclonal and Polyclonal Antibodies Research
  • Click Chemistry and Applications
  • Chemical Synthesis and Analysis
  • Advanced biosensing and bioanalysis techniques
  • Advanced Biosensing Techniques and Applications
  • Mosquito-borne diseases and control
  • Travel-related health issues
  • Malaria Research and Control
  • Assistive Technology in Communication and Mobility
  • Innovative Teaching Methods
  • Island Studies and Pacific Affairs
  • ICT in Developing Communities
  • Learning Styles and Cognitive Differences
  • Various Chemistry Research Topics
  • Education Systems and Policy
  • Protein Degradation and Inhibitors
  • Labor Movements and Unions
  • Experimental Learning in Engineering
  • Hearing Loss and Rehabilitation
  • Innovation and Socioeconomic Development
  • Engineering Education and Curriculum Development
  • Design Education and Practice

University of Bristol
2024-2025

University of St Andrews
2021-2024

Otago Polytechnic
2021

Tauranga Hospital
2021

Ottawa University
2019

Institute for Systems Biology
2019

North Seattle College
2019

California Institute of Technology
2015-2018

The pandemic was a very difficult time for everyone, as well teachers and their students. Teachers of first-year quantitative chemistry courses, both during the postpandemic, encountered many pandemic-induced difficulties, including inter alia communicating with individual students, providing them rapid formative feedback, determining where they were on learning journey. In addition, two cohorts students requiring different teaching approaches enrolled this course period study (2020–2023)....

10.1021/acs.jchemed.4c00705 article EN cc-by Journal of Chemical Education 2025-02-11

Abstract We describe a general synthetic strategy for developing high‐affinity peptide binders against specific epitopes of challenging protein biomarkers. The epitope interest is synthesized as polypeptide, with detection biotin tag and strategically placed azide (or alkyne) presenting amino acid. This (SynEp) incubated library complementary alkyne or peptides. Library elements that bind the SynEp in correct orientation undergo Huisgen cycloaddition, are covalently linked to SynEp. Hit...

10.1002/anie.201505243 article EN Angewandte Chemie International Edition 2015-09-17

Protein catalyzed capture agents (PCCs) are synthetic antibody surrogates that can target a wide variety of biologically relevant proteins. As step toward developing high-throughput PCC pipeline, we report on the preparation barcoded rapid assay platform for analysis hits from library screens. The is constructed by first surface patterning micrometer scale barcode composed orthogonal ssDNA strands onto glass slide. slide then partitioned into microwells, each which contains multiple copies...

10.1021/acs.analchem.8b00706 article EN Analytical Chemistry 2018-07-06

Abstract We describe a general synthetic strategy for developing high‐affinity peptide binders against specific epitopes of challenging protein biomarkers. The epitope interest is synthesized as polypeptide, with detection biotin tag and strategically placed azide (or alkyne) presenting amino acid. This (SynEp) incubated library complementary alkyne or peptides. Library elements that bind the SynEp in correct orientation undergo Huisgen cycloaddition, are covalently linked to SynEp. Hit...

10.1002/ange.201505243 article EN Angewandte Chemie 2015-09-17

Abstract Objectives To comparatively evaluate a low‐cost otoscope with traditional device among health care workers in Malawi. Methods The study is prospective, comparative, qualitative observational survey of worker's opinions using 5‐point Likert rating scales and tick box categories 10‐item questionnaire. Twenty‐five mixed cadre from the Ear, Nose, Throat Department Queen Elizabeth Hospital, Blantyre Malawi were recruited. Outcomes measures used ease speculum attachment, handling,...

10.1002/lio2.601 article EN Laryngoscope Investigative Otolaryngology 2021-06-10

Abstract Objectives To comparatively evaluate a low cost ‘frugal’ otoscope in resource settings with traditional device amongst health care workers Malawi. Design A prospective, comparative, qualitative observational survey of healthcare opinions using 5-point Likert rating scales and tick box categories. Setting Participants 25 mixed cadre from the Ear, Nose Throat department Malawi were recruited. Main outcome measures 10-item questionnaire was used to compare device. Outcomes ease...

10.22541/au.170665210.05304588/v1 preprint EN Authorea (Authorea) 2024-01-30

The first few weeks in a university level chemistry laboratory can be daunting and off-putting. Student safety is paramount, but, despite the best efforts of technicians demonstrators, they cannot everywhere. Here we describe development testing an immersive, virtual reality (VR) simulation to teach correct glassware assembly procedure before entering wet lab. Before attempting assemble reflux real life, year students were taught via one three interventions: VR game, online or watching...

10.26434/chemrxiv-2024-66p8h preprint EN cc-by-nc 2024-10-25

Purpose: Imported malaria is the principle, preventable life-threatening infection among Canadians travelling abroad. The Canadian Malaria Network (CMN) supplies information and parenteral therapies to healthcare providers treating severe complicated malaria. CMN data gathers surveillance on these cases. Methods & Materials: Data characteristics, risk factors, clinical outcomes of cases in Canada from January 2014 December 2017 were analyzed. Results: There 367 treated with therapy...

10.1016/j.ijid.2018.11.054 article EN cc-by-nc-nd International Journal of Infectious Diseases 2019-01-30

Purpose: Background: Malaria continues to be a top travel-acquired cause of morbidity among ill returning VFRs and migrants Canada. We examined the demographic travel correlates Canadian with malaria over 5-year period illuminate characteristics this disease in our traveling population. Methods & Materials: Methods: Data on returned VFR travelers presenting GeoSentinel Surveillance network (CanTravNet) site between April 2013 March 2018 who were diagnosed analyzed. Results: Of 4434...

10.1016/j.ijid.2018.11.234 article EN cc-by-nc-nd International Journal of Infectious Diseases 2019-01-30
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