A5014251885- Nutritional Studies and Diet
- Diet and metabolism studies
- Nutrition and Health in Aging
- Obesity, Physical Activity, Diet
- Bariatric Surgery and Outcomes
- Consumer Attitudes and Food Labeling
- Body Composition Measurement Techniques
- Muscle metabolism and nutrition
- Nutrition, Genetics, and Disease
- Obesity and Health Practices
- Esophageal and GI Pathology
- Vitamin D Research Studies
- Sodium Intake and Health
- Agricultural safety and regulations
- Behavioral Health and Interventions
- Tea Polyphenols and Effects
- Metabolomics and Mass Spectrometry Studies
- Coffee research and impacts
- Health Promotion and Cardiovascular Prevention
- Biotin and Related Studies
- Genetics, Aging, and Longevity in Model Organisms
- Frailty in Older Adults
- Health and Lifestyle Studies
- Cardiovascular Health and Risk Factors
- Nutrition, Health and Food Behavior
Wageningen University & Research
2016-2025
BACKGROUND―Findings from animal and epidemiological research support the potential neuroprotective benefits healthy diets. However, to establish diet-neuroprotective causal relations, evidence dietary intervention studies is needed. NU-AGE first multicenter assessing whether a diet targeting health in aging can counteract age-related physiological changes different organs, including brain. In this study, we specifically investigated effects of NU-AGE's on cognitive decline. MATERIALS AND...
Dietary modulation of the gastro-intestinal microbiota is a potential target in improving healthy ageing and age-related functional outcomes, including cognitive decline. We explored association between diet, cognition Dutch older adults 'New dietary strategies addressing specific needs elderly population for aging Europe' (NU-AGE) study. The profile 452 fecal samples from 226 subjects was determined using 16S ribosomal RNA gene-targeted microarray. intake assessed by 7-day food records....
Background: Nutrition-related knowledge (NRK) and nutrition-related attitudes (NRAs) are necessary for dietary changes toward healthier patterns. In turn, patterns can be beneficial in maintaining health of older adults. Therefore, the aim this cross-sectional study was to investigate whether NRK NRAs were associated with lifestyle features among adults (65+ years) from five European countries (France, Italy, Poland, Netherlands United Kingdom). Methods: Within project NU-AGE, 1,144 healthy...
Background: The Mediterranean Diet has been proposed as an effective strategy to reduce inflammaging, a chronic low grade inflammatory status, and thus, slow down the aging process. We evaluated whether Mediterranean-like dietary pattern specifically targeting recommendations of people aged over 65 years (NU-AGE diet) could be shift intake older adults towards healthful diet. Methods: Adults 65–80 across five EU-centers were randomly assigned NU-AGE diet group or control group. followed one...
The Mediterranean diet (MD) is widely recommended for the prevention of chronic disease, but evidence a beneficial effect on bone health lacking. aim this study was to examine Mediterranean-like dietary pattern [NU-AGE (New Dietary Strategies Addressing Specific Needs Elderly Population Healthy Aging in Europe)] indexes inflammation with number secondary endpoints, including mineral density (BMD) and biomarkers collagen degradation 1-y multicenter randomized controlled trial (RCT; NU-AGE)...
The aim of this work was to examine the cross-sectional relationship between body composition (BC) markers for adipose and lean tissue bone mass, a wide range specific inflammatory adipose-related in healthy elderly Europeans.A whole-body dual-energy X-ray absorptiometry (DXA) scan made 1121 (65-79 years) women men from five European countries "New dietary strategies addressing needs population aging Europe" project (NCT01754012) cohort measure mass. Pro-inflammatory (IL-6, IL-6Rα, TNF-α,...
With aging, energy needs decrease, necessitating a more nutrient-dense diet to meet nutritional needs. To bridge this gap, the use of foods, fortified and dietary supplements can be important. This observational study aims describe current micronutrient intakes Dutch elderly identify contribution intake micronutrients that are often inadequately consumed in elderly. Data 245 volunteers from NU-AGE aged 65 80 years were used. Dietary was assessed by means 7-day food records, supplement...
While an adequate protein intake is important for the maintenance of muscle mass during ageing, amount and source necessary optimal prevention sarcopenia remains to be determined. The present study aimed investigate influence dietary proteins on risk in a cohort 65–79-year-old European adults within frame NU-AGE study. A total 986 participants were included analysis. Skeletal index (SMI), assessed by dual-energy X-ray absorptiometry (DXA), handgrip strength (HG) employed create continuous...
Sarcopenia is characterised by a progressive loss of skeletal muscle mass and physical function as well related metabolic disturbances. While fibre-rich diets can influence health outcomes, the impact on yet to be determined, moderating effects activity (PA) need considered. The aim present study was examine links between fibre intake, in cohort older adults from NU-AGE study. In 981 (71 ± 4 years, 58% female), assessed using short-physical performance battery test handgrip strength....
Body composition (BC) is an emerging important factor for the characterization of metabolic status. The assessment BC has been studied in various populations and diseases such as obesity, diabetes, endocrine well physiological paraphysiological conditions growth aging processes, physical training. A gold standard technique human at molecular level represented by dual-energy X-ray absorptiometry (DXA), which able to precisely assess measure body mass (and areal bone mineral density-aBMD) on a...
Dietary fat subtypes may play an important role in the regulation of muscle mass and function during ageing. The aim present study was to determine impact isocaloric macronutrient substitutions, including different subtypes, on sarcopenia risk older men women, while accounting for physical activity (PA) metabolic risk. A total 986 participants, aged 65–79 years, completed a 7-day food record wore accelerometer week. continuous sex-specific score (SRS), skeletal assessed by dual-energy X-ray...
Lifelong daily multivitamin supplementation is highly recommended after sleeve gastrectomy (SG). Based on previous research, a specialized supplement (MVS) for SG patients was developed and optimized (WLS Optimum 1.0 2.0). This study presents its mid-term effectives compares micronutrient status of using this MVS to users standard (sMVS) non-users during the first three years post-surgery.Of 226 participants that were included at baseline, yearly follow-up blood tests completed by 193 (85%)...
Purpose: Onset of type 2 diabetes (T2D) is often gradual and preceded by impaired glucose homeostasis. Lifestyle interventions including weight loss physical activity may reduce the risk developing T2D, but adherence to a lifestyle change challenging. As part an international T2D prevention trial (PREVIEW), behavior intervention supported participants in achieving healthier diet physically active lifestyle. Here, our aim was explore influence this behavioral program (PREMIT) on...
Dietary glycaemic index (GI) and load (GL) are indices used to quantify the effect of carbohydrate quality quantity on postprandial glycaemia. GI/GL-health associations widely studied but data validity integrated GI/GL measurements scarce. We evaluated performance a food-frequency questionnaire (FFQ) specifically developed assess GI/GL. In total, 263 Dutch men 212 women (aged 55 ± 11 years) completed 58-item GI-FFQ, an 183-item general-FFQ 2-day 24 h-recall donated blood for glycated...
Maintenance of high physical performance during aging might be supported by an adequate dietary intake niacin, vitamins B-6 and B-12, folate because these B are involved in multiple processes related to muscle functioning. However, not much is known about the association between performance. The objectives this study were investigate older adults explore mediation niacin status homocysteine concentrations. We used baseline data from New Dietary Strategies Addressing Specific Needs Elderly...