A5101866830- Lanthanide and Transition Metal Complexes
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Ferroptosis and cancer prognosis
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- RNA Interference and Gene Delivery
- Transition Metal Oxide Nanomaterials
- Protein Degradation and Inhibitors
- Pancreatic and Hepatic Oncology Research
- interferon and immune responses
- Cancer, Hypoxia, and Metabolism
- Supercapacitor Materials and Fabrication
- Ubiquitin and proteasome pathways
- Gut microbiota and health
- Glycosylation and Glycoproteins Research
- Peptidase Inhibition and Analysis
- Dendrimers and Hyperbranched Polymers
- Advanced Polymer Synthesis and Characterization
- Inflammatory Biomarkers in Disease Prognosis
- Advancements in Battery Materials
- Lung Cancer Research Studies
- Lipid Membrane Structure and Behavior
Affiliated Hospital of Qingdao University
2024
Qingdao University
2024
Wuxi Ninth People's Hospital
2024
Soochow University
2024
Taiyuan University of Technology
2024
Southern Medical University
2022-2023
Shanxi Medical University
2021-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Wuhan University of Technology
2016
Abstract Accurate identification and visualization of peritoneal metastases (PM) are clinically essential to improving the prognosis for gastric cancer. However, owing multifocal spread metastasis nodules, small size, close contact with adjacent organs, identifying completely removing them during surgery is extremely challenging, resulting in cancer treatment failure recurrence. This study develops a T 1 ‐weighted magnetic resonance imaging (MRI) contrast agent (FeGdNP)‐loaded indocyanine...
Magnetic resonance imaging (MRI) is recognized as the most powerful clinical modality due to its ability produce detailed three-dimensional anatomical images and high spatial resolution in a non-invasive manner without use of harmful radioactive nuclides or ionizing radiation. Conventional small molecule contrast agents (CAs) for MRI, such paramagnetic transition metal ion chelates iron oxide nanoparticles, are limited by lower relaxivity, shorter blood circulation time their potential toxic...
Novel mesoporous silica nanoparticles conjugated with hyaluronic acid and RGD peptide were developed for dual-receptor mediated targeting drug delivery.
Abstract Magnetic resonance imaging (MRI) has been widely using in clinical diagnosis, and contrast agents (CAs) can improve the sensitivity MRI. To overcome problems of commercial Gd chelates-based T 1 CAs, magnetic iron oxide nanoparticles (MIONs)-based 2 reported exceedingly small MIONs (ES-MIONs)-based this study, a facile co-precipitation method was developed to synthesize biodegradable biocompatible ES-MIONs with excellent water-dispersibility poly (aspartic acid) (PASP) as stabilizer...
A smart MRI contrast agent that is almost not responsive to normal physiological conditions, but highly acidic and reductive TME, realized CC-MRI, significantly enhanced the between tumors livers.
Fluorine-19 magnetic resonance imaging (19F MRI) probes have received considerable research interest as contrast agents (CAs), but they remain neglected and underutilized due to the limited fluorine content or poor performance of fluorinated tracers. Here, we present polymeric nanoparticles (NPs) 19F MRI CAs with a simple synthesis method promising performance. First, hydrophilic random copolymers were synthesized from oligo(ethylene glycol) methyl ether acrylate perfluoropolyether...
The gut microbiota and its associated metabolites play a critical role in shaping the systemic immune response influencing efficacy of immunotherapy. In this study, patients with extensive-stage small cell lung cancer (ES-SCLC) were included to explore correlation between immunotherapy ES-SCLC. Pre- post-treatment, we collected stool samples from 49 ES-SCLC treated an anti-programmed death-ligand 1 (PD-L1) antibody. We then applied 16S ribosomal RNA (rRNA) sequencing liquid...
19F magnetic resonance imaging (MRI)-assisted drug delivery provides the possibility to monitor and track transportation details in situ. A series of photo-responsive amphiphilic block copolymers consisting hydrophilic poly(ethylene glycol) 19F-containing hydrophobic segments, poly(2,2,2-trifluoroethyl acrylate) (PTFEA), with different chain lengths were synthesized by reversible addition–fragmentation chain-transfer polymerization. In particular, photo-sensitive functional group...