Lin Huang

ORCID: 0000-0002-0611-985X
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Research Areas
  • Advanced Photocatalysis Techniques
  • Electrospun Nanofibers in Biomedical Applications
  • Bone Tissue Engineering Materials
  • Nanoplatforms for cancer theranostics
  • Gas Sensing Nanomaterials and Sensors
  • Wound Healing and Treatments
  • Polymer Surface Interaction Studies
  • Advancements in Battery Materials
  • Advanced Battery Materials and Technologies
  • Silk-based biomaterials and applications
  • Lanthanide and Transition Metal Complexes
  • Solar Thermal and Photovoltaic Systems
  • Tissue Engineering and Regenerative Medicine
  • Greenhouse Technology and Climate Control
  • Copper-based nanomaterials and applications
  • Nerve injury and regeneration
  • Luminescence Properties of Advanced Materials
  • Advanced Nanomaterials in Catalysis
  • Solar Radiation and Photovoltaics
  • Luminescence and Fluorescent Materials
  • solar cell performance optimization
  • 3D Printing in Biomedical Research
  • Nanoparticle-Based Drug Delivery
  • Advanced Sensor and Energy Harvesting Materials
  • Advanced Battery Technologies Research

Xi'an University of Architecture and Technology
2018-2025

China Academy of Engineering Physics
2021-2024

Zhejiang Sci-Tech University
2023-2024

Southern Medical University
2021-2024

Jiangnan University
2022-2024

Southern University of Science and Technology
2024

Wuhan University
2017-2023

Central South University
2020-2023

Laser Fusion Research Center
2022-2023

Laser Research Institute
2023

Ferroptosis therapy (FT) efficacy of tumors suffers from a relatively low concentration Fenton agents, limited hydrogen peroxide (H2O2) content, and insufficient acidity in the tumor environment (TME), which are unfavorable for reactive oxygen species (ROS) generation based on or Fenton-like reactions. The glutathione (GSH) overexpression TME can scavenge ROS abate FT performance. In this study, strategy storm specifically initiated by our developed nanoplatforms (TAF-HMON-CuP@PPDG) is...

10.1021/acsnano.3c01369 article EN ACS Nano 2023-06-07

Abstract The emerging tumor ferroptosis therapy confronts impediments of the microenvironment (TME) with weak intrinsic acidity, inadequate endogenous H 2 O , and a powerful intracellular redox balance system that eliminates toxic reactive oxygen species (ROS). Herein, strategy Fenton reaction cycloacceleration initiated by remodeling TME for magnetic resonance imaging (MRI)‐guided high‐performance tumors is proposed. synthesized nanocomplex exhibits enhanced accumulation at carbonic...

10.1002/adhm.202203362 article EN Advanced Healthcare Materials 2023-03-09

Bacterial cellulose (BC) membranes are used as the carrier for berberine hydrochloride and sulphate to produce a new controlled release system. Release studies transdermal experiments were carried out in vitro. Carrier BC can significantly extend drug time, contrast existing commercial carriers. Freeze-dried 10 mm thick optimized delivery. The lowest rate was simulated gastric fluid (SGF) or H2SO4 solution, highest intestinal (SIF) an intermediate found alkaline conditions. curves closely...

10.1039/c3tb20149j article EN Journal of Materials Chemistry B 2013-01-01

3D bioprinting, a promising technology by precisely positioning cell-laden biomaterials to fabricate complex functional artificial tissues and organs, has potential applications in regenerative medicine drug discovery. However, the printing of large-scale constructs with high structural fidelity is still major challenge. One main bottlenecks development bioink materials. Herein, double network hydrogel that combines superior shear-thinning recovery properties gellan gum (GG) rapid UV...

10.1016/j.matdes.2018.09.040 article EN cc-by-nc-nd Materials & Design 2018-09-25

Berberine hydrochloride (BH) possesses various pharmacological properties including anticancer; unfortunately, it has low oral bioavailability and potential side effects for its parenteral administration. Nanoscale delivery carriers can increase the of BH. Chitosan interesting biopharmaceutical such as nontoxicity, biocompatibility, biodegradability, mucoadhesiveness, ability to open epithelial tight junctions. This study aims engineer a chitosan-coated nano-liposomal carrier The engineered...

10.1039/c4tb00876f article EN Journal of Materials Chemistry B 2014-01-01

The nerve guidance conduit (NGC) is a promising clinical strategy for regenerating the critical-sized peripheral injury. In this study, polysaccharide chitin used to fabricate hydrogel film inducing impaired sciatic regeneration through incorporating conductive poly(3,4-ethylenedioxythiophene) nanoparticles (PEDOT NPs) and modifying with cell adhesive tetrapeptide Cys–Arg–Gly–Asp (CRGD) (ChT-PEDOT-p). partial deacetylation process of exposing amino groups performed (i) improve electrostatic...

10.1021/acsami.1c01904 article EN ACS Applied Materials & Interfaces 2021-03-31

BiVO4-based composites are of great interest as photocatalysts for water oxidation, CO2 reduction, and organic pollutant degradation, but their low charge separation efficiency poor photocatalytic activity still need to be resolved. Herein, metallic Cu Bi nanoparticle-co-decorated BiVO4 (Cu–Bi/BiVO4) microplates were constructed via a simple solvothermal method, was evaluated by reduction with H2O vapor. The obtained results demonstrated that the Cu–Bi/BiVO4 exhibited high visible-light...

10.1021/acsanm.1c00115 article EN ACS Applied Nano Materials 2021-03-30

Hollow mesoporous organosilica nanoparticles (HMONs) are widely considered as a promising drug nanocarrier, but the loaded drugs can easily leak from HMONs, resulting in considerably decreased loading capacity and increased biosafety risk. This study reports smart use of core/shell Fe3O4/Gd2O3 (FG) hybrid gatekeeper to block pores which yield an unreported large content (up 20.4%) DOX. The conjugation RGD dimer (R2) onto DOX-loaded HMON with FG capping (D@HMON@FG@R2) allowed for active...

10.1021/acs.nanolett.1c03130 article EN Nano Letters 2021-11-05

Abstract A prevalent problem of magnetic resonance imaging (MRI) contrast agents (CAs) for drug loading applications is easy aggregation. The major concern hollow mesoporous organosilica nanoparticles (HMONs) hard control untimely leakage. To overcome both problems, a new strategy limited‐space controlled aggregation generic enhancement capability proposed. Typically, MRI CAs exceedingly small gadolinium oxide nanoparticle (GO) and Gd poly(acrylic acid) macrochelate (GP) are exploited to...

10.1002/adfm.202209278 article EN Advanced Functional Materials 2022-11-20

Recently, nanozymes with peroxidase (POD)-like activity have shown great promise for ferroptosis-based tumor therapy, which are capable of transforming hydrogen peroxide (H2O2) to highly toxic hydroxyl radicals (•OH). However, the unsatisfactory therapeutic performance due insufficient endogenous H2O2 and acidity at sites has always been a conundrum. Herein, an ultrasmall gold (Au) @ ferrous sulfide (FeS) cascade nanozyme (AuNP@FeS) H2S-releasing ability constructed Au nanoparticle (AuNP)...

10.1021/acsami.3c09066 article EN ACS Applied Materials & Interfaces 2023-09-23

10.1016/j.jmbbm.2018.11.002 article EN Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2018-11-19
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