A5101549806- Synthesis and biological activity
- Plant-based Medicinal Research
- Asymmetric Synthesis and Catalysis
- Crystal structures of chemical compounds
- Phenothiazines and Benzothiazines Synthesis and Activities
- Liver physiology and pathology
- Molecular Sensors and Ion Detection
- Hepatitis C virus research
- Synthetic Organic Chemistry Methods
- Advanced Polymer Synthesis and Characterization
- Advanced Chemical Sensor Technologies
- Catalytic Alkyne Reactions
- Multicomponent Synthesis of Heterocycles
- Drug-Induced Hepatotoxicity and Protection
- Cancer Treatment and Pharmacology
- Carbohydrate Chemistry and Synthesis
- Immune cells in cancer
- Atherosclerosis and Cardiovascular Diseases
- Advanced Synthetic Organic Chemistry
- Angiogenesis and VEGF in Cancer
- Ionic liquids properties and applications
- Analytical Chemistry and Chromatography
- Extraction and Separation Processes
- Analytical Chemistry and Sensors
- Drug Solubulity and Delivery Systems
Sichuan University
2009-2024
Jiangnan University
2024
Chengdu University
2015-2020
The University of Texas at Austin
2010
Washington University in St. Louis
2009
A modular and convenient synthesis of ethynyl end functionalized poly(3-hexylthiophene) in high purity is reported; this material facilitated access to poly(3-hexylthiophene)-block-poly(acrylic acid) which self-assembled into hierarchical structures.
In this study, a new ternary choline chloride-deep eutectic solvent was used to efficiently extract bioactive polysaccharides from poria cocos assisted by the tool of far infrared radiation (FIR) together with hot air circulation (HAC).
A large amount of evidence suggests that monocytes/macrophages infiltration is implicated in a variety inflammatory diseases including acute liver injury. Monocyte chemoattractant protein 1 (MCP-1) plays crucial role the process macrophages recruitment. We herein presented small-molecule library and feasible quick screening method evaluating potency inhibition chemotaxis RAW264.7 cells stimulated by MCP-1. Fifty-three small molecules were synthesized screened, four compounds (2g, 2h, 4f, 6h)...
Amphiphilic polymer nanoparticles loaded with silver cations or/and N-heterocyclic carbene–silver complexes were assessed as antimicrobial agents against Gram-negative pathogens Escherichia coli and Pseudomonas aeruginosa.
To achieve sensitive, selective and facile detection of hydrazine in environmental biological systems, a fluorescent probe (Che-Dcv) with unique nonaromatic fluorophore was developed. Upon addition 20% DMSO-PBS buffer (pH = 7.4, 10 mM, v/v) at room temperature, the displayed strong emission 496 nm along color change from brown-red to yellow. The response attributed reaction dicyanovinyl groups afford hydrazone, which supported by 1H NMR HRMS. limit Che-Dcv for estimated be as low 1.08 ppb...
For the first time, a new magnetic separation strategy for of alkaloids from <italic>Coptis chinensis</italic> was developed in this study.
A fluorescent probe for phenylhydrazine detection was developed with aldehyde as the recognition group and good selectivity towards over hydrazine, hydroxylamine other amines observed. Its application in real water samples fast visualization of using a probe-loaded paper strip were demonstrated.
<p dir="ltr"><b>Abstract</b></p><p dir="ltr">Diabetes is a significant global public health issue<a href="" target="_blank"> with implications for vascular</a> endothelial cells (ECs) dysfunction and the subsequent development advancement of diabetic complications. This study aims to compare cellular molecular properties aorta in normal streptozotocin (STZ)-induced mice, focus on elucidating potential mechanism underlying EC dysfunction. Here, we...
<p dir="ltr"><b>Abstract</b></p><p dir="ltr">Diabetes is a significant global public health issue<a href="" target="_blank"> with implications for vascular</a> endothelial cells (ECs) dysfunction and the subsequent development advancement of diabetic complications. This study aims to compare cellular molecular properties aorta in normal streptozotocin (STZ)-induced mice, focus on elucidating potential mechanism underlying EC dysfunction. Here, we...
A series of symmetrical 1,4-disubstituted buta-1,3-diynes is prepared with excellent yields (up to 95%) through homocoupling terminal alkynes catalyzed by a copper salt under solvent-free conditions. This method provides an environmentally friendly process prepare 1,3-diynes in short reaction times mild Furthermore, the suitable for wide substrate scope and has functional group compatibility. The can also be scaled up gram level.
Hydroxy-α-sanshool was synthesized in a 13% overall yield through eight steps, which included two Wittig reactions that were used to form the carbon skeleton with ethyl 2-oxoacetate and 2 E,4 E-hexadienal being reacted appropriate ylides. Impurities processes could easily be separated. Ethyl 6-hydroxy-2Z-hexenoate converted its E-isomer catalysis by I 2E,6Z,8E,10E-dodecatetraenoic acid crystallized from solution 1% acetate n-hexane.