A5073955536- Advanced Polymer Synthesis and Characterization
- Hydrogels: synthesis, properties, applications
- Supramolecular Self-Assembly in Materials
- Electrocatalysts for Energy Conversion
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Asymmetric Synthesis and Catalysis
- Thermal and Kinetic Analysis
- Multicomponent Synthesis of Heterocycles
- Catalytic Processes in Materials Science
- Luminescence and Fluorescent Materials
- Heavy metals in environment
- Coordination Chemistry and Organometallics
- Analytical chemistry methods development
- Wound Healing and Treatments
- Dyeing and Modifying Textile Fibers
- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Analysis
- Photochromic and Fluorescence Chemistry
- Anesthesia and Sedative Agents
- Fuel Cells and Related Materials
- Synthesis and Catalytic Reactions
- Graphite, nuclear technology, radiation studies
- Anesthesia and Pain Management
- Heavy Metals in Plants
Tsinghua University
2018-2025
Henan University
2024
Shenzhen Institutes of Advanced Technology
2024
Anshun University
2024
Zhongyuan University of Technology
2024
National Center for Nanoscience and Technology
2024
Chinese Academy of Sciences
2024
Guizhou Normal University
2024
Forschungszentrum Jülich
2024
Peking University First Hospital
2022-2024
A self-healing hydrogel enriched with properties from a double-dynamic network (DDN) that has been prepared via two dynamic linkages (imine and borate ester) by using single polymeric cross-linker. The four-component Ugi reaction was used for easily synthesizing multifunctional poly(ethylene glycol) (MF-PEG) benzaldehyde group phenylboronic acid at each end of the chain. This MF-PEG simultaneously cross-linked poly(vinyl alcohol) through ester glycol chitosan an imine to generate unique DDN...
The first phosphine-catalyzed [5+1] annulation of enones with<italic>N</italic>-sulfonylimines works efficiently to give tetrahydropyridines.
Radioprotectors for acute injuries caused by large doses of ionizing radiation are vital to national security, public health and future development humankind. Here, we develop a strategy explore safe efficient radioprotectors combining Hantzsch's reaction, high-throughput methods polymer chemistry. A water-soluble with low-cytotoxicity an excellent anti-radiation capability has been achieved. In in vivo experiments, this is even better than amifostine, which the only approved radioprotector...
A multi-responsive self-healing hydrogel for the controlled release of curcumin has been developed using dynamic boronic acid ester linkages.
Nonbactericidal polymers that prevent bacterial attachment are important for public health, environmental protection, and avoiding the generation of superbugs. Here, inspired by physical bactericidal process carbon nanotubes graphene derivatives, we develop nonbactericidal resistant to using multicomponent reactions (MCRs) introduce molecular "needles" (rigid aliphatic chains) "razors" (multicomponent structures) into polymer side chains. Computer simulation reveals occurrence spontaneous...
To evaluate the efficacy and safety of HSK3486 for induction maintenance general anesthesia in elective surgical patients, but excluding emergency, cardiothoracic, cerebral endoscopic sinus cases.A total 40 eligible patients were randomly assigned to (n = 30) or propofol 10) dosage groups a ratio 3:1. Drugs administered as bolus injection 0.4 mg/kg (HSK3486) 2.0 (propofol) induction, followed by infusion with same anesthetic. An additional 6 non-randomized received (2.0 mg/kg) given...
Hydrogels are soft, tissue-like materials that have great potential as wound dressings. However, most hydrogels unsatisfactory in achieving whole-layer regeneration of diabetic wounds due to the complex pathological microenvironment and irregular shapes. Here, a glucose-responsive self-adaptive phenylboronic acid (PBA) hydrogel solubilized strong antioxidant flavonoids (Gel-Flavonoids) is developed via dynamic borate bonds. The Gel-Flavonoids system can spontaneously confirm shape release...
Abstract Electrocatalysts with a hollow nanocage structure and single atoms (SAs) incorporated into layered double hydroxide (LDH) are highly significant for enhancing the efficiency of electrochemical water splitting. In this study, efficient robust electrocatalyst oxygen evolution reaction (OER) is successfully fabricated by confining Ru SAs within made NiFe LDH. An etching co‐precipitation method used making LDH nanocages integrating to produce Ru‐SAC/NiFe The architecture increases...
Dynamic covalent chemistry, which renders reusable and degradable thermoset polymers, is a promising tool for solving the global problem of plastic pollution. Although dynamic chemistry can construct polymer networks, it rarely introduces other functions into limits development functional materials. Herein, we develop heterocycle-based demonstrate reversibility aza-Michael addition reaction between heterocycle dihydropyrimidin-2(1H)-thione electron-deficient olefins. Our method produces...
Formaldehyde (FA) has been detected via the Hantzsch reaction for many decades. However, rarely used to detect FA in biological systems due disadvantages of small-molecule probes (including toxicity and poor water solubility). In this study, polymeric fluorescent were developed resolve these issues associated with small molecules, living was successfully reaction. These water-soluble polymers easily scaled-up (∼25 g) by radical polymerization using commercial monomers. exhibited similar,...
In this paper, an antioxidant self-healing hydrogel has been prepared. The Biginelli reaction was used to prepare a monomer containing phenylboronic acid (PBA) and 3,4-dihydropyrimidin-2(1H)-one (DHPM) groups. This PBA-DHPM copolymerized with poly(ethylene glycol methyl ether) methacrylate (PEGMA) produce water-soluble copolymer via radical polymerization. resulting quickly crosslinked poly(vinyl alcohol) (PVA) through borate ester bonds generate under mild conditions (pH ∼ 7.4, 25 °C)....
Multifunctional hydrogels are typically constructed from multifunctional polymers that synthesized through tedious multistep processes. Here, a poly(ethylene glycol) (MF-PEG) containing phenylboronic acid and phenolic groups at the ends was prepared via one step Ugi reaction, which greatly simplified preparation of this polymer. The resulting MF-PEG can cross-link poly(vinyl alcohol) dynamic borate ester linkages to quickly generate self-healing hydrogel under mild conditions (∼10 s, pH ∼...
A phenylboronic acid (PBA)-containing copolymer was synthesized <italic>via</italic> the Hantzsch reaction and radical polymerization. Curcumin dynamically included in this PBA-containing polymer to selectively kill cancer cells.
The development of high quality magnetic self-healing hydrogels containing well-dispersed nanoparticle has been a challenging procedure due to unavailable methods facilely introducing groups that can efficiently stabilize these nanoparticles in the hydrogels. In this research, polymer both phenylboronic acid (PBA) and phosphonic (PA) developed by Kabachnik–Fields (KF) reaction. This well disperses iron oxide (IONPs) through strong interactions between PA surface IONPs; thus, effectively...
Heavy-metal poisoning is a global concern; therefore, safe and efficient chelators against acute chronic heavy-metal are vital for public health. Here we developed strategy to explore polymer by combining the Kabachnik–Fields reaction chemistry. A water-soluble with considerable metal-chelating ability antioxidant capability was obtained. During in vivo experiments, this effectively prevented cadmium mice which there no antidote; prevention effect significantly superior clinically available...
Sunscreen is recommended to protect human skin from ultraviolet (UV) radiation damage and cancer development. However, small-molecule organic UV filters in sunscreens the environment may pose a health risk users through transdermal action because of their small molecular weights. Here we report strategy for realizing safe coral-friendly polymeric by combining Biginelli reaction free radical polymerization. We have obtained water-soluble polymer with excellent absorbance that effectively...
Synthetic antioxidants have long been used to protect edible oils from oxidation. However, concerns about their potential health risks and environmental impact led a growing interest in natural antioxidants. In this study, we explore the antioxidant properties of extracts four
In this communication, a chiral squaramide-catalyzed asymmetric dearomative tandem annulation reaction of unmodified Morita-Baylis-Hillman alcohols with azomethine imines has been achieved through kinetic resolution MBH under mild conditions, giving pharmaceutically interesting functionalized hetero-bicyclo[3.3.1]nonane derivatives in good to excellent yields enantioselectivities.