A5038341338- Neurobiology of Language and Bilingualism
- Dementia and Cognitive Impairment Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Genomic variations and chromosomal abnormalities
- Neurological disorders and treatments
- Dysphagia Assessment and Management
- Parkinson's Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Cancer Genomics and Diagnostics
- Functional Brain Connectivity Studies
- Epilepsy research and treatment
- Glycosylation and Glycoproteins Research
- Language Development and Disorders
- Genetic factors in colorectal cancer
- Neurological Disease Mechanisms and Treatments
- Voice and Speech Disorders
- Hallucinations in medical conditions
- Spatial Neglect and Hemispheric Dysfunction
- Cerebrovascular and Carotid Artery Diseases
- Diverse Topics in Contemporary Research
- Cerebrovascular and genetic disorders
- Sarcoma Diagnosis and Treatment
- Treatment of Major Depression
- Cognitive Functions and Memory
- Psychosomatic Disorders and Their Treatments
University of Ulsan
2010-2022
Asan Medical Center
2011-2022
Ulsan College
2009-2022
Neurology, Inc
2017-2022
Dankook University Hospital
2008
Dankook University
2006-2007
Catholic University of America
2003
The Montreal Cognitive Assessment (MoCA) is a brief cognitive screening tool with high sensitivity for patients mild impairment (MCI). authors examined the validity and reliability of Korean version MoCA (MoCA-K) in elderly outpatients. MoCA-K, Mini-Mental State Examination (MMSE), Clinical Dementia Rating (CDR) scale, neuropsychological batteries were administered to 196 persons (mild Alzheimer's disease [AD] = 44, MCI 37, normal controls [NC] 115). MoCA-K scores highly correlated those...
Abstract To elucidate the pathogenesis of hepatocellular carcinoma (HCC) and develop useful prognosis predictors, it is necessary to identify biologically relevant genomic alterations in HCC. In our study, we defined recurrently altered regions (RARs) common many cases HCCs, which may contain tumor‐related genes, using whole‐genome array‐CGH explored their associations with clinicopathologic features. Gene set enrichment analysis was performed investigate functional implication RARs. On an...
Oro-pharyngeal dysphagia is a common symptom in patients with Parkinson's disease (PD) and related disorders, even their early stage of diseases. Dysphagia these has been underdiagnosed, probably due to poor the self-awareness conditions underuse validated tools objective instruments for assessment. The detection intervention are closely improving quality life decreasing mortality rate patients. purpose this paper give an overview characteristics dysphagia, including epidemiology,...
To study dysphagia in pure, unilateral medullary infarction using video fluoroscopic swallowing (VFS) tests and to compare the results between lateral (LMI) medial (MMI).We studied 46 patients with (37 LMI, 9 MMI). Based on MRI findings, each LMI was classified rostrocaudally as either a rostral or caudal lesion, horizontally superficial (lateral + dorsal) nonsuperficial lesion. Each MMI assigned deep (lesion extending dorsal surface) lesion group. VFS examination conducted an 8-point scale...
Although many genomic alterations have been observed in lung cancer, their clinicopathologic significance has not thoroughly investigated. This study screened the aberrations across whole genome of non-small cell cancer cells with high-resolution and investigated implications.One-megabase resolution array comparative hybridization was applied to 29 squamous carcinomas 21 adenocarcinomas lung. Tumor normal tissues were microdissected extracted DNA used directly for without amplification. The...
Abstract Background and purpose As part of network‐specific neurodegeneration, changes in cerebellar gray matter (GM) volume impaired cerebello–cerebral functional networks have been reported Alzheimer disease (AD). Compared with healthy controls, a loss the cerebellum has observed patients continuum AD. However, little is known about anatomical or clinical AD but no brain amyloidosis. We aimed to identify relationship between dementia conversion amyloid‐negative mild cognitive impairment...
As the fiberoptic gastroscopy using midazolam is being in widespread use, exact nature of on memory should be clarified. We intended to examine whether causes selective anterograde amnesia and what impact it has other aspects general cognitive function.We recruited healthy subjects undergoing under conscious sedation. At baseline, history taking for retrograde Korean version Montreal Cognitive Assessment were performed. A man's name address given immediately after intravenous administration....
Hyperacusis, an increased sensitivity to auditory stimulation,1 may occur in patients with peripheral system dysfunction, migraine, depression, and certain infectious diseases. However, hyperacusis is a rare manifestation of CNS lesions.2 Previous studies have reported paracusia (altered perception loudness, timbre, or pitch) palinacousis (perseveration aural sensation) after medial geniculate body hemorrhage,3 hallucination due pontine hemorrhage,4 bilateral caudal tectal hemorrhage.5 We...
Buccofacial apraxia (BFA, or oral apraxia) is a nonspeech skilled movement disorder that involves orofacial structures in the absence of paresis. BFA usually co-occurs with aphasia speech (AOS) and isolated an extremely rare phenomenon. The brain regions correlated have been studied patients concomitant limb apraxia. Therefore, exact responsible for remain unclear. We report patient pure discuss localization lesion.
This study aimed to investigate the applicability of deep learning (DL) model using diffusion-weighted imaging (DWI) data predict severity aphasia at an early stage in acute stroke patients.
<b><i>Background:</i></b> The underlying mechanism of transcortical sensory aphasia (TSA) caused by lesions occurring in the left frontal lobe remains unclear. We attempted to investigate with use functional MRI (fMRI). <b><i>Methods:</i></b> studied 2 patients TSA after a infarction identified diffusion-weighted MRI. As control subjects, patient motor and healthy normal adult were chosen. Korean version Western Aphasia Battery was performed...
The orthographic system of the Korean language consists both phonogram (Hangul) and ideogram (Hanja). We report 2 patients who revealed selective impairment in reading either orthographies after brain damages. YJ, a 67-year-old man, showed Broca’s aphasia severe apraxia speech stroke left inferior parietal lobe. He demonstrated predominant difficulties phonogram. KS, 51-year-old woman, had an intracerebral hemorrhage She anomic on ideogram. These findings support notion that recognition...
Abstract We describe a patient who had an isolated tongue tremor with audible click after gamma knife radiosurgery for acoustic schwannoma. The nature of the was clearly demonstrated by videofluoroscopy. possible pathogenic mechanisms are discussed. © 2004 Movement Disorder Society
Palinacousis, an auditory illusion in which perceived aural sensations persist or recur after the initial acoustic stimulus has ceased,1 may be caused by structural lesions involving temporal lobe. However, reported were usually extensive, and detailed imaging tests rarely performed.2-4 We report a patient with transient palinacousis following discrete lobe intracerebral hemorrhage (ICH). A 67-year-old hypertensive woman suddenly developed language disturbances. On examination next day, she...
Agrammatic primary progressive aphasia (PPA-G) has been known to be associated with focal brain atrophy involving the left posterior frontal and anterior insular regions. However, can also rarely result from right hemispheric lesions in right-handed patients, so-called crossed dextrals (CAD). We report two patients PPA-G whose 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) showed hypometabolism predominantly hemisphere, implicating “crossed PPA-G.”
Objectives: Individuals with nonfluent agrammatic aphasia show impaired production and comprehension of time reference via verbal morphology. However, cross-linguistic findings to date suggest inconsistent evidence as whether tense processing in general is or the past selectively difficult this population. This study examined verb morphology Korean-speaking individuals aphasia. Methods: A group 9 healthy controls 8 (5 for task) participated study. Sentence priming auditory sentence picture...
The purpose of this study was to investigate changes in thermal adaptive properties for the elderly haenyeos by a questionnaire and local cold tolerance test. We carried out an one-on-one Jeju, Korea. A total 112 hanyeos (68±8 yr age) 177 (66±8 yr) participated survey. main survey consisted 37 questions related demographic characteristics (3 questions), diving practices suits (12 behavioral temperature regulation (22 questions). As test, finger cold-induced vasodilation (CIVD) at 4℃ were...