A5101871170- Rheumatoid Arthritis Research and Therapies
- Advanced biosensing and bioanalysis techniques
- Cancer Cells and Metastasis
- Estrogen and related hormone effects
- Gastric Cancer Management and Outcomes
- Sirtuins and Resveratrol in Medicine
- Genomics, phytochemicals, and oxidative stress
- Autophagy in Disease and Therapy
- Digestive system and related health
- Menopause: Health Impacts and Treatments
- Gastrointestinal Tumor Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cytokine Signaling Pathways and Interactions
- RNA Interference and Gene Delivery
- Telomeres, Telomerase, and Senescence
- Occupational and environmental lung diseases
- Spondyloarthritis Studies and Treatments
Hebei Medical University
2025
Jilin University
2021
Xi'an Honghui Hospital
2018
Xi'an Jiaotong University
2018
Second Military Medical University
2017
Changhai Hospital
2017
Air Force Medical University
2015
Xijing Hospital
2015
First Hospital of Xi'an
2015
Changsha Medical University
1999
Abstract Purpose: Increasing the central dose for large, locally advanced, drug-resistant gastrointestinal stromal tumors (LADR-GIST) has consistently been a significant challenge. This study aims to evaluate feasibility of using stereotactic ablation radiotherapy enhance radiation delivered center large LADR-GISTs.
Methods and Materials: involved five patients with LADR-GIST who were treated CyberKnife. The gross tumor volume (GTV) was delineated as multi-shell structure. Five...
Autophagy plays a double‐edged sword for cancer; particularly, mitophagy important roles in the selective degradation of damaged mitochondria. However, whether is involved killing effects tumor cells by ionizing radiation (IR) and its underlying mechanism remain elusive. The purpose to evaluate mitochondrial ROS (mROS) on autophagy after IR; furthermore, we hypothesized that KillerRed (KR) targeting mitochondria could induce mROS generation, subsequent depolarization, accumulation Pink1,...
Emergence of resistance, unavoidable systemic toxicity and unsatisfactory efficacy arethe main obstacles for traditional cancer therapy. Combination with phosphorothioate modified antisense oligonucleotides (PS‑ASODN) against human telomerase reverse transcriptase (hTERT) may enhance the therapeutic effect irradiation. However, PS‑ASODN hTERT on anti‑tumor effects irradiation in liver remain unclear. In current study, Walker 256 cells were transfected PS‑ASODN. Cell proliferation cell...
Background and Objective: Interferon (IFN)-γ plays crucial roles in the development of ankylosing spondylitis (AS) though regulating its sensitive response genes, but genes to IFN-γ dysregulation AS are partially reported.Thus, present study explored potential target for treatment under interferon-γ (IFN-γ) stimulated condition.Materials Methods: The gene expression profile, GSE11886 was downloaded.The differentially expressed (DEGs) non-INF-γ group INF-γ were revealed respectively, followed...