- Dialysis and Renal Disease Management
- Hepatitis C virus research
- Chronic Kidney Disease and Diabetes
- Hepatitis B Virus Studies
- Central Venous Catheters and Hemodialysis
- Diabetes Treatment and Management
- Renal Diseases and Glomerulopathies
- Pharmacological Effects and Toxicity Studies
- Acute Kidney Injury Research
- Parathyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Neurological and metabolic disorders
- Potassium and Related Disorders
- Renal Transplantation Outcomes and Treatments
- Systemic Lupus Erythematosus Research
- Complement system in diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Muscle and Compartmental Disorders
- Hepatitis Viruses Studies and Epidemiology
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Electrolyte and hormonal disorders
- Diabetes Management and Research
- Health Systems, Economic Evaluations, Quality of Life
The First Affiliated Hospital, Sun Yat-sen University
2024-2025
Zhongshan Hospital
2024-2025
Fudan University
2024-2025
Sun Yat-sen University
2024-2025
China Medical University Hospital
2015-2024
China Medical University
2015-2024
National Yang Ming Chiao Tung University
2012-2023
China Medical University
2010-2021
National Cheng Kung University Hospital
2020
Zhangzhou Municipal Hospital of Fujian Province
2019
Background. The impact of dialysis modality on the rates and types infectious complications has not been well studied. aim present investigation was to evaluate hepatitis C virus (HCV) B (HBV) infections in peritoneal (PD) haemodialysis (HD) patients Asia-Pacific region. Methods. study included most recent period-prevalent data recorded national or regional registries 10 countries/areas (Australia, New Zealand, Japan, China, Taiwan, Korea, Thailand, Hong Kong, Malaysia India), where such...
Bifidobacterium and Lactobacillus can beneficially affect the host by producing acetic acid lactic acid, which lower pH thereby inhibit growth of pathogens or allow probiotic bacteria to compete with for epithelial adhesion sites nutrients. The transmural migration enteric organisms into peritoneal cavity cause peritonitis in dialysis (PD) patients. We hypothesized that composition intestinal microbiota regard species differed between PD patients healthy controls. aim study was investigate...
Background and objectives Patients with CKD can benefit from an increase in physical activity. Walking is one of the most common exercises patients CKD; however, association walking outcomes not clear. This study investigated overall mortality RRT stages 3–5. Design, setting, participants, & measurements All 3–5 program China Medical University Hospital June 2003 to May 2013 were enrolled. The risks analyzed using competing-risks regressions. Results A total 6363 (average age, 70 years)...
In type II diabetic patients, a better glycaemic control has been reported to slow down the progression of nephropathy. The effect pre-dialysis on long term prognosis in diabetics haemodialysis is still uncertain. purpose this study evaluate before starting maintenance clinical outcome patients.One hundred and thirty-seven receiving regular single university hospital were enrolled. patients classified as either good or poor group according their within 6 months haemodialysis. Serum albumin,...
Comparisons of survival in patients on peritoneal dialysis (PD) and hemodialysis (HD) have been conducted many Western countries, but publications this subject Asian populations are scarce. The present study estimated the relative mortality hazard for HD PD Taiwan.Incident end-stage renal disease reported to Taiwan Renal Registry during 1995 - 2002 were included study. Patients had be 20 years age or older survived first 90 days dialysis. A total 45,820 incident 2,809 formed population....
ABSTRACT. Tubulointerstitial nephritis is a main renal manifestation caused by pathogenic leptospira that accumulate mostly in the proximal tubules, thereby inducing tubular injury and tubulointerstitial nephritis. To elucidate role of outer membrane proteins nephritis, from Leptospira shermani nonpathogenic patoc extracted Triton X-114 were administered to cultured mouse tubule cells. A dose-dependent increase monocyte chemoattractant protein–1 (MCP-1), RANTES, nitrite, tumor necrosis...
Nephrologists commonly recommend continuous ambulatory peritoneal dialysis (CAPD) with break-in periods of at least 2 weeks. We investigated the safety and feasibility shorter following surgical implantation Tenckhoff catheters.We retrospectively examined 310 patients that underwent catheter for first time. The early group comprised 226 started CAPD ≤ 14 days after implantation; late 84 > implantation. Catheter-related complications within 6 months were analyzed.A total enrolled. Time to...
Patients with CKD receiving maintenance dialysis are at risk for upper gastrointestinal bleeding. However, the of bleeding in patients early who not is unknown. The hypothesis was that their negatively linked to renal function. To test this hypothesis, association between eGFR and stages 3-5 were analyzed.Patients program from 2003 2009 enrolled prospectively followed until December 2012 monitor development analyzed using competing-risks regression time-varying covariates.In total, 2968 a...
In order to investigate the prevalence of antibody hepatitis C virus (anti-HCV) in renal transplant patients, evolution anti-HCV status, and clinical outcome anti-HCV-positive allograft recipients, we tested sera from 120 patients for anti-HCV. Thirty-eight were B surface antigen (HBsAg)-positive. Two anti-delta-positive. A total 79 (65.8%) had at least one serum positive Anti-HCV positivity decreased after transplantation more than 5 years (65.5% versus 37.9%, 78.3± 13.4 months later)....
Pruritus is a common and frustrating symptom in hemodialysis (HD) patients 5-D itch scale proposed as reliable measurement of pruritus. However, information regarding categories currently unavailable. We explored optimal cut-offs itching based on numerical rating (NRS) HD patients. Four hundred nine China Medical University Hospital December 2014 were included severity pruritus was estimated using NRS scale. The association analyzed by linear regression. for generated. average 3.4 ± 3.0 the...
Abstract. Tubulointerstitial nephritis is the main manifestation of acute renal damage caused by leptospirosis, but mechanism remains unexplored. Patients infected with Leptospira shermani in Taiwan disclosed tubular dysfunction particularly medullary thick ascending limb loop Henle (mTAL), and related seems to be underestimated. To elucidate damage, outer membrane protein extract from was administered a model cultured mTAL cells derived normal mice. The addition L. induced significant...
This study is to describe our clinical experience of diffuse alveolar hemorrhage (DAH) in patients with systemic lupus erythematosus (SLE) Taiwan. From July 1994 June 2001, eight DAH among 1541 different SLE (0.52%) admitted the Chang Gung Memorial Hospital were included for chart review. Dyspnea (100%) and fever (87.5%) most common symptoms instead hemoptysis (62.5%). The extrapulmonary presentation was renal involvement (100%), which nephritis, nephrotic syndrome or acute failure. overall...
Mortality rates of cirrhotic patients with renal failure admitted to the medical intensive care unit (ICU) are high. End-stage liver disease is frequently complicated by disturbances function. This investigation aimed compare predicting ability acute physiology, age, chronic health evaluation II and III (APACHE III), sequential organ assessment (SOFA), Child-Pugh scoring systems, obtained on first day ICU admission, for hospital mortality in critically ill failure.Sixty-seven cirrhosis were...
Abstract: Uremic pruritus is one of the common complications in long‐term dialysis patients. Recently, researchers reported that immunohypothesis with high serum level cytokines could be cause uremic pruritus. Polymethylmethacrylate (PMMA) artificial kidney (AK) has been to adsorb more than other high‐flux AKs. In July 2006, 30 patients severe from 300 chronic hemodialysis (HD) a single center entered this prospective study. Their dialyzers were changed PMMA AK for 4 weeks. The severity was...
Abstract Background The status of immunocompromised patients is well recognized in end stage renal disease (ESRD). As described recently, this acquired immune dysfunction the uremic milieu may be one main pathogenic factors for mortality ESRD. aim study was to determine relationship between response following a hepatitis B vaccination (HBV vaccination) and survival maintenance dialysis patients. Methods A total 156 (103 on hemodialysis 53 continuous ambulatory peritoneal dialysis) were...
This study compared the risk of subdural hematoma (SDH) and subsequent mortality in hemodialysis (HD) peritoneal dialysis (PD) patients with ESRD.Claims data were obtained from National Health Insurance Administration Research Database Taiwan. retrospective cohort comprised 10,136 PD HD newly diagnosed ESRD 1998 to 2010. Patients matched by propensity score year initiation. Incidence rates hazard ratios SDH as well odds 30-day deaths evaluated date first session when was diagnosed, or renal...