A5101649220- Nanoplatforms for cancer theranostics
- Silicon Nanostructures and Photoluminescence
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Catalytic Cross-Coupling Reactions
- Photoacoustic and Ultrasonic Imaging
- Synthetic Organic Chemistry Methods
- Polymer Surface Interaction Studies
- Advanced Sensor and Energy Harvesting Materials
- Anodic Oxide Films and Nanostructures
- Nanowire Synthesis and Applications
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Extracellular vesicles in disease
- Semiconductor materials and devices
- Advanced Nanomaterials in Catalysis
- RNA Interference and Gene Delivery
- Transportation Safety and Impact Analysis
- Surface Modification and Superhydrophobicity
- Magnesium Oxide Properties and Applications
- Electromagnetic Launch and Propulsion Technology
- Mesoporous Materials and Catalysis
- Electrospun Nanofibers in Biomedical Applications
- High-Velocity Impact and Material Behavior
- Diatoms and Algae Research
- Dielectric materials and actuators
Fudan University
1997-2025
Wuhan University
2024
Renmin Hospital of Wuhan University
2024
Beijing University of Chemical Technology
2018-2020
Abstract The application of plasmonic dimeric nanostructures in color displays, data storage, and especially metamaterials necessitates the patterning dimers into ordered arrays, but controllable assembly nanoparticles patterned dimer arrays on substrates still remains a challenge. Here, facile laser‐scanning‐based strategy to fabricate quasi‐3D nanoparticle with controlled orientation for information encryption is reported. Laser scanning polymer‐covered (e.g., gold) selectively exposes...
Abstract Nanoparticle (NP)‐based vehicles are attractive for biomedical delivery and therapy, owing to improved therapeutic efficiency reduced adverse effects compared free drugs. Uncontrolled NP heterogeneity at the suspension level or single particle poses grand challenges in effective use of NPs biology medicines. Precision nanoparticles (PNPs) a class discrete nanostructures exhibiting elaborately tailored surface structural heterogeneity, but minimal variations between one solution....
Nitrogen heterocyclic carbenes (NHCs) are emerging as effective substitutes for conventional thiol ligands in surface functionalization of nanoparticles (NPs), offering exceptional stability to NPs under harsh conditions. However, the highly reactive feature NHCs limits their use introducing chemically active groups onto NP surface. Herein, we develop a general yet robust strategy efficient with copolymer bearing various functional groups. The polymer consist multiple block, utilized binding...
Nitrogen heterocyclic carbenes (NHCs) are emerging as effective substitutes for conventional thiol ligands in surface functionalization of nanoparticles (NPs), offering exceptional stability to NPs under harsh conditions. However, the highly reactive feature NHCs limits their use introducing chemically active groups onto NP surface. Herein, we develop a general yet robust strategy efficient with copolymer bearing various functional groups. The polymer consist multiple block, utilized binding...
Abstract Ultrasmall silica‐based nanoparticles (SNPs) are attractive for application in many fields, but existing synthetic approaches show limited control over the size and morphology of these SNPs. This study describes a general single copolymer chain‐mediated strategy scalable synthesis highly monodispersed symmetric asymmetric SNPs with sub‐50 nm diameter. Random copolymers poly(acrylic acid‐ r ‐styrene) intramolecularly collapse into ultrasmall single‐chain serve as seeds to template...
Arrays of nanoparticle (NP) clusters with controlled architectures show broad applications in nanolasers, sensors, and photocatalysis, but the fabrication these arrays on substrates remains a grand challenge. This review presents highly effective polymer-based strategy for process-directed self-assembly binary polyelectrolyte-grafted NPs (PGNPs) bearing opposite charges into stable colloidal molecules (CMs) via electrostatic interactions. The coordination number (x) ABx CMs can be tuned by...
Designing artificial enzymes for in vivo catalysis presents a great challenge due to biomacromolecule contamination, poor biodistribution, and insufficient substrate interaction. Herein, we developed single-chain polymeric nanoparticles with Cu/N-heterocyclic carbene active sites (SCNP-Cu) function as peroxidase mimics chemo-dynamic therapy (CDT). Compared the enzyme based on unfolded linear polymer scaffold multichain cross-linked scaffold, SCNP-Cu exhibits improved tumor accumulation CDT...
Abstract Polymer‐grafted hairy nanoparticles (HNPs) that combine the unique properties of inorganic (NPs) and polymers are attractive building blocks for layer‐by‐layer assembly functional hybrid materials, but adsorption behaviors HNPs on substrates remain unclear. This article describes a systematic study charged polymer‐grafted oppositely in different solvent media via combination experiments simulations. It is shown simulations process associated with release counterions around HNPs,...
The combination of photothermal therapy with chemotherapy has emerged as a promising therapeutic modality for addressing triple-negative breast cancer (TNBC). This manuscript describes novel hybrid nanoplatform comprising ultrathin catalytic platinum/gold (Pt/Au) nanotubes encapsulated docetaxel and phase-change materials (PCMs) the photoacoustic imaging-guided synergistic chemo-photothermal TNBC. Upon irradiation near-infrared laser, heating converts solid-state PCM into liquid, triggering...
Abstract Self‐assembly of gold nanoparticles demonstrates a promising approach to realize enhanced photoacoustic imaging (PAI) and photothermal therapy (PTT) for accurate diagnosis efficient cancer therapy. Herein, unique assemblies with tunable patterns (including arcs, rings, ribbons, vesicles) on poly(lactic‐ co ‐glycolic acid) (PLGA) spheres are constructed taking advantage emulsion‐confined polymer‐directed self‐assembly strategies. The influencing factors formation mechanism produce...
A porous Si (PS) layer with a spongy microstructure on top of dendritic was fabricated moderately doped p-type wafer using two-step anodization process. This illustrates that in addition to substrate doping, current density also has an effect the microstructure. preoxidation heat treatment spongy-type found change structure significantly, making it more difficult fully oxidize at low temperatures. However, can better withstand without suffering noticeable changes structure. X-ray...
A series of low temperature processes incorporated in the silicon on insulator (SOI) formation using Si molecular beam epitaxial growth porous dramatically reduces impurity ramp‐up from substrate and lowers doping level layer. double‐layer system with a spongy microstructure layer top dendritic was fabricated moderately doped p‐type wafer two‐step anodization process, used as for epitaxy. An extended annealing high vacuum found to be helpful stabilizing making it less susceptible change...
Abstract Ultrathin inorganic nanowires are an emerging class of building blocks for creating functional materials and devices, but there remains challenging to fine‐tune the structure property at molecular level. Here, this work shows that ultrathin polymer‐grafted gold (PG‐AuNWs) can exhibit bottlebrush polymer‐like physical behaviors macroscopic properties. The hybrid PG‐AuNWs in solutions show viscoelasticity which be finely regulated by controlling structural parameters (e.g., length...