A5101689967- Geophysical and Geoelectrical Methods
- ECG Monitoring and Analysis
- Non-Invasive Vital Sign Monitoring
- Maritime Navigation and Safety
- Hemodynamic Monitoring and Therapy
- Advanced Algorithms and Applications
- Optimal Experimental Design Methods
- Phonocardiography and Auscultation Techniques
- Underwater Acoustics Research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Geochemistry and Geologic Mapping
- Heart Rate Variability and Autonomic Control
- Geophysical Methods and Applications
- Advanced Sensor and Control Systems
- Advanced Statistical Process Monitoring
- Alzheimer's disease research and treatments
- Neural Networks and Applications
- Embedded Systems and FPGA Design
- Metal complexes synthesis and properties
- Remote-Sensing Image Classification
- Seismic Waves and Analysis
- Ship Hydrodynamics and Maneuverability
- Synthesis of Organic Compounds
- Cancer, Hypoxia, and Metabolism
- Chemotherapy-induced organ toxicity mitigation
Jilin University
2012-2024
China University of Geosciences
2024
Wuxi Institute of Technology
2022
Southern Medical University
2013-2020
Nanfang Hospital
2017-2020
Jilin Medical University
2019
Beijing Institute of Technology
2016
China Pharmaceutical University
2011-2015
State Council of the People's Republic of China
2015
Anhui Provincial Hospital
2015
Cetuximab (C225) is a unique agent, targeting epidermal growth factor receptor (EGFR)-positive cancer. However, the therapeutic effect of C225 in EGFR high-expressing non-small cell lung cancer (NSCLC) remains poor. Here, we report that conjugation with gold nanoparticles (AuNPs) enhances cytotoxicity NSCLC both vitro and vivo. The lines A549 (EGFRhigh) H1299 (EGFRlow) were employed to investigate different responses C225, IgG-AuNPs C225-AuNPs. antitumor properties C225-AuNPs explored vivo...
Heart sounds are an important basis for evaluating heart disease. In recent years, auxiliary diagnosis technology of cardiovascular disease based on the detection sound signals has become a research hotspot. A lightweight automatic classification method is presented in this study. It only needs to perform simple pre-processing data, and neural network model constructed automatically extract time-frequency features data: where convolution module extracts frequency domain characteristics, loop...
Abstract This is a roadmap article with multiple contributors on different aspects of embodying intelligence and computing in the mechanical domain functional materials structures. Overall, an IOP broad, multi-author review leaders field discussing latest developments, commissioned by editorial board. The intention here to cover various topics adaptive structural material systems mechano-intelligence overall roadmap, twelve sections total. These from devices systems, such as computational...
Dimercaptosuccinic acid (DMSA) modified ultra-small particles of iron oxide (USPIO) were synthesized through a two-step process. The first step: oleic (OA) capped Fe3O4 (OA-USPIO) by novel oxidation coprecipitation method in H2O/DMSO mixing system, where DMSO acts as an oxidant simultaneously. second OA was replaced DMSA to obtain water-soluble nanoparticles. as-synthesized nanoparticles characterized TEM, FTIR, TGA, VSM, DLS, EDS and UV–vis. Hydrodynamic sizes Peroxidase-like catalytic...
The study reported in this paper aimed to analyze vessel traffic characteristics the Singapore Strait. Real-time automatic identification system (AIS) data, with about 4 million records, were collected from Lloyd's Marine Intelligence Unit database for analysis. results showed that containerships made up largest proportion (36.36%) of Strait, while roll-on-roll-off and passenger ships only a small percentage (4.77%). analysis suggested special attention should be paid tankers, bulk carriers,...
With the development of hyperspectral sensors, availability images (HSIs) has increased significantly, prompting advancements in deep learning-based image classification (HSIC) methods. Recently, graph convolutional networks (GCNs) have been proposed to process graph-structured data non-Euclidean domains, and used for HSIC. The superpixel segmentation should be implemented first GCN-based methods, however, it is difficult manually select optimal sizes obtain useful information...
The artifacts of ECG signals include baseline wander (BW), muscle (EMG) artifact, electrode motion artifact and power line interference. In order to get the optimal robust de-noising algorithm among generally used methods based on stationary wavelet transform (SWT), we adjust signal-to-noise ratio (SNR) noisy signal from 1 db 10 db, evaluate results by means SNR visual inspection, then conclude using Symlet4, decomposition at level 5, hard shrinkage function with empirical Bayesian (EBayes)...
A grounded electrical source airborne transient electromagnetic (GREATEM) system on an airship enjoys high depth of prospecting and spatial resolution, as well outstanding detection efficiency easy flight control. However, the movement swing front-fixed receiving coil can cause severe baseline drift, leading to inferior resistivity image formation. Consequently, reduction drift GREATEM is vital importance inversion explanation. To correct a traditional interpolation method estimates...
The photoplethysmography (PPG) is inevitably corrupted by many kinds of noise no matter whether its acquisition mode transmittance or reflectance. To enhance the quality PPG signals, studies have made great progress in denoising adding extra sensors and developing complex algorithms. Considering reasonable cost, compact size, real-time easy implementation, this study proposed a simple method based on double median filters which can be integrated microcontroller commercial portable pulse...
Conventional immunohistochemistry is limited to subjective judgment based on human experience and thus it clinically required develop a quantitative immunohistochemical detection.
Clinical studies have shown that melatonin lowers the frequency of thrombocytopenia in patients with cancer undergoing radiotherapy or chemotherapy. Here, we investigated mechanisms by which promotes platelet formation and survival. Our results show exerted protective effects on serum-free induced apoptosis CHRF megakaryocytes (MKs). Melatonin promoted MK colony forming units (CFUs) a dose-dependent manner. Using doxorubicin-treated cells, found rescued G2/M cell cycle arrest doxorubicin....
Since goaf water can cause inrush, collapse or other severe geological hazards in coal mining, its detection has become a significant issue. As the grounded electrical source airborne transient electromagnetic (GREATEM) system provide considerable prospecting depth, lateral resolution, and high efficiency, method may be suitable for detection. To verify feasibility, field survey over Qinshui mine (Shanxi province, China) was conducted, used to detect geoelectric characteristics of water....
The direct intramolecular acylation of esters was developed by using the combined system FeCl3 with Cl2CHOCH3. This unique cooperative offered a new and efficient approach to biologically important xanthone chromone derivatives regioselectivity. Examples were reported, control experiments carried out examine effect benzyl
The noninvasive peripheral oxygen saturation (SpO2) and the pulse rate can be extracted from photoplethysmography (PPG) signals. However, accuracy of extraction is directly affected by quality signal obtained peak identified; therefore, a hybrid wavelet-based method proposed in this study. Firstly, we suppressed partial motion artifacts corrected baseline drift using wavelet based on principle multiresolution. And then, designed quadratic spline modulus maximum algorithm to identify PPG...
A series of small molecules had been designed, synthesized, and evaluated as multifunctional ligands against Alzheimer's disease (AD).
To study synergistic effects of nedaplatin and cisplatin on three human carcinoma cell lines (esophageal line Eca-109, ovarian Skov-3 cervical Hela).Inhibition were evaluated by MTT assay apoptosis was detected flow cytometry. In addition, changes Ki-67, Bax Bcl-2 at mRNA protein levels quantified RT-PCR Western blotting.Growth inhibition in each dose-dependent after exposure to or alone. The interaction the two drugs higher concentrations according median-effect principle. rates with...
This case-control study aimed to investigate potential associations between interleukin ( IL ) gene polymorphisms and the risks of developing extremity posttraumatic osteomyelitis (PTOM) in Chinese Han population. Altogether, 189 PTOM patients 200 healthy controls were genotyped IL-1α (rs17561, rs1800587), IL-1β (rs16944, rs1143627, rs1143634, rs2853550), IL-1RN (rs4251961, rs419598, rs315951), IL-4 (rs2243248, rs2243250), IL-6 (rs1800795, rs1800796, rs1800797), IL-8 (rs4073, rs2227306,...
Cancer-related malnutrition is a mortal threat to gastric carcinoma patients. However, conventional nutrition treatment not effective for recovery. Recombinant human GH (rhGH) widely accepted clinically treat severe caused by non-malignant diseases, but approved malignant diseases due the safety concern. To explore of rhGH on cancer, we assessed effect two tumor-bearing mice models in vivo established adenoma cell lines SGC-7901 and MKN-45. VEGF expression tumor tissues was detected using...
Pulse signals are widely used to evaluate the status of human cardiovascular, respiratory, and circulatory systems. In process being collected, usually interfered by some factors, such as spike noise poor-sensor-contact noise, which have severely affected accuracy subsequent detection models. recent years, methods been applied processing above noisy signals, dynamic time warping, empirical mode decomposition, autocorrelation, cross-correlation. Effective they are, those complex difficult...