To determine (1) between-hospital variation in diuretic use for infants with bronchopulmonary dysplasia (BPD), including hospital-specific treatment frequency, duration, and percentage of receiving short (≤5 consecutive days) versus longer (>5 courses, to (2) demographic clinical variables associated administration.A retrospective cohort study was conducted the Pediatric Health Information System utilization patterns (primary outcome) among <29-week-gestation evolving BPD at age 28 days who...

Objective: To determine the practice variance, prevalence, and economic burden of clinically diagnosed gastroesophageal reflux disease (GERD) in preterm infants. Methods: Applying a retrospective cohort study design, we analyzed data from 18 567 infants 22 to 36 weeks’ gestation &amp;gt;400 g birth weight NICUs 33 freestanding children’s hospitals United States. GERD comorbidities, demographic factors were examined for their association with average length stay (LOS) hospitalization cost....

We tested the hypothesis that Respiratory Severity Score (RSS) on day of life 30 is predictive mortality and length mechanical ventilation in premature infants prolonged ventilation.A retrospective chart review was performed using Nationwide Children's Hospital medical record Vermont-Oxford Network databases. The primary outcome variable survival to hospital discharge secondary after 30.We identified 199 neonates admitted between 2004 2007 with birth weight less than 1,500 g received first...

Objective To determine demographic and clinical variables associated with inhaled corticosteroid administration to evaluate between-hospital variation in steroid use for infants bronchopulmonary dysplasia (BPD). Design Retrospective Cohort Study. Setting Neonatal units of 35 US children's hospitals; as recorded the Pediatric Health Information System (PHIS) database. Patients 1429 evolving BPD at 28 days who were born <29 weeks gestation birth weight <1500 grams, admitted within first 7...

Purpose.: To measure the binocular contrast sensitivity (CS) of newborn infants using a fixation-and-following card procedure. Methods.: The CS 119 healthy was measured stimuli printed on cards under descending method limits (93 infants) and randomized/masked designs (26 infants). One experienced one novice adult observer tested vertical square-wave gratings (0.06 0.10 cyc/deg; 20/10,000 20/6000 nominal Snellen equivalent); also horizontal (0.10 cyc/deg) Method Constant Stimuli while being...

This research was prospectively designed to determine whether a 0.083 cycles per degree (cy/deg) (20/7200) square-wave stimulus is good choice for clinical measurement of newborn infants' contrast sensitivity and the function (CSF) infant band-pass. The results were retrospectively analyzed method constant stimuli (MCS) descending limits (dLIM) yielded similar results.In across-subjects experimental designs, pilot experiment used MCS (N = 47 visual acuity; N 38 at cy/deg), main dLIM 22...

To describe inter-center hospital variation in inhaled nitric oxide (iNO) administration to infants born prior 34 weeks' gestation at US children's hospitals.This was a retrospective cohort study using the Pediatric Health Information System determine frequency, age first administration, and length of iNO use among 22 699 consecutive admissions unique <34 admitted 37 hospitals from January 1, 2007, through December 31, 2010.A total 1644 (7.2%) received during their hospitalization, with...

Abstract Objective To compare exclusive breastfeeding (BF) and BF initiation among 185 women with Type 1 212 2 pregestational diabetes who intended or partial delivered at ≥34 weeks of gestation. Methods Retrospective cohort study. At discharge, is direct complemented expressed breast milk. defined by BF. Results groups were similar in prior experience (69 vs 67%) but different intention to exclusively (92 78%) partially (8 22%). Women the group younger (median age 30 33y), likely be...

Introduction The rise in antimicrobial resistance is a major global concern and requires new treatment strategies. use of helper compounds, such as thioridazine (TDZ), an antipsychotic drug, combination with traditional antibiotics must be investigated. Objectives aim this study was to investigate the efficacy TDZ compound for dicloxacillin (DCX) against methicillin-resistant Staphylococcus aureus (MRSA) vivo, compare DCX+TDZ vancomycin (VAN). Methods Mice were inoculated intraperitoneal...

Timely delivery and magnesium sulfate (MgSO4) are mainstay in the treatment of preeclampsia with severe features (PWSF). Premature delivery, severity illness mother-infant separation may increase risk for breastfeeding (BF) initiation failure.To compare BF among women late-onset PWSF treated MgSO4 to without (WOSF) who did not receive MgSO4.Retrospective study 158 104 WOSF delivered at ≥34 weeks. Intention BF, formula feed (FF) or partially was declared prenatally. At discharge, exclusive...

Acupuncture is one of the most widely used forms traditional Chinese medicine often referred to as alternative therapy in Western World and over past decades it has become increasingly popular Denmark. Pneumothorax known common serious complication following acupuncture, but quite rarely reported. During a three-month period two patients with pneumothorax caused by acupuncture were admitted our department. The purpose this case report increase awareness complication, which may not be so uncommon.

Inducible nitric oxide (NO) synthase (iNOS) is a stress response protein upregulated in inflammatory conditions, and NO may suppress cellular proliferation. We hypothesized that preventing L-arginine (L-arg) uptake endothelial cells would prevent lipopolysaccharide/tumor necrosis factor-α (LPS/TNF)-induced, NO-mediated suppression of Bovine pulmonary arterial (bPAEC) were treated with LPS/TNF or vehicle (control), either 10 mM L-leucine [L-leu; competitive inhibitor L-arg by the cationic...

Introduction Conservative treatment solutions against aortic prosthetic vascular graft infection (APVGI) for inoperable patients are limited. The combination of antibiotics with antibacterial helper compounds, such as the neuroleptic drug thioridazine (TDZ), should be explored. Aim To investigate efficacy conservative systemic dicloxacillin (DCX) in TDZ (DCX+TDZ), compared to DCX alone, early APVGI caused by methicillin-sensitive Staphylococcus aureus (MSSA) a porcine model. Methods...

OBJECTIVE: To compare multiparous women with pregestational diabetes mellitus (PGDM) and without prior breastfeeding (BF) experience to ascertain their infants’ feeding type during hospitalization at discharge. METHODS: A retrospective cohort study of 304 PGDM who delivered ≥34 weeks gestational age (GA). Prior BF infant preference was declared prenatally. At discharge, defined as exclusive or partial. RESULTS: no groups were similar in 1 2, race number pregnancies. Women had more...

Background: Peripherally inserted central catheters (PICCs) are used routinely in neonatal care. Measures of surface anatomy have been to estimate appropriate PICC depth neonates since 1973. However, prior research using anthropometric measures proper insertion has limited pediatric and adult literature. Purpose: The purpose this study was explore the relationships among a neonate's depth. Methods: Neonates requiring at Nationwide Children's Hospital were enrolled between January September...

Asymptomatic infants born to women with pregestational diabetes mellitus (PGDM) are usually admitted the well baby nursery (WBN) while those who symptomatic or in need of specialized care neonatal intensive unit (NICU).To determine if changes NICU admission rate asymptomatic PGDM during two different epochs affected breastfeeding (BF) initiation rates.Retrospective cohort investigation 386 and their delivered 2008-11 (epoch 1) 457 2013-16 2) at a single institution.NICU admissions:...

To examine the effects of early breastfeeding (eBF) or formula feeding (eFF) on hypoglycemia and BF initiation in infants born to women with pregestational diabetes mellitus (PGDM) who intended BF. Retrospective cohort investigation 554 PGDM their (IDMs) delivered during 2008-2016. The first (BF FF) was considered if given within 4 hours from birth. 282 (51%) IDMs were admitted Well Baby Nursery. Of 134 whose BF, affected 30% which corrected oral feedings 78% cases. At discharge, 49%...

To ascertain the rate of in-hospital supplementation as it relates to early breastfeeding (BF) and formula feeding (FF) its effects on BF (exclusive partial) at time discharge for infants born women with pregestational diabetes mellitus (PGDM).Retrospective cohort investigation 282 PGDM who intended their asymptomatic admitted newborn nursery blood glucose monitoring routine care. Early was defined by initial if given within four hours birth.Of mother-infant dyads, 134 (48%) 148 (52%) FF....