Sheng Huang

ORCID: 0000-0003-3608-8078
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About
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Research Areas
  • Radical Photochemical Reactions
  • Sulfur-Based Synthesis Techniques
  • Hydrogels: synthesis, properties, applications
  • Ammonia Synthesis and Nitrogen Reduction
  • Wound Healing and Treatments
  • Oxidative Organic Chemistry Reactions
  • Advanced Synthetic Organic Chemistry
  • Silk-based biomaterials and applications
  • Advanced biosensing and bioanalysis techniques
  • Quinazolinone synthesis and applications
  • RNA Interference and Gene Delivery
  • Nanopore and Nanochannel Transport Studies
  • Phenothiazines and Benzothiazines Synthesis and Activities

Southwest Medical University
2025

East China University of Technology
2023

Fujian Medical University
2020-2022

Comprehensive Summary The dearomatization of indole derivatives bearing amide functionalities presents a significant challenge due to the inherent stability carbonyl group, resulting from nitrogen lone‐pair delocalization that imparts increased resonance stabilization. In this study, we report visible‐light photocatalytic intramolecular with groups, achieving synthesis spiroindolines via energy transfer. This method enables efficient formation range hydroxyl‐substituted in moderate high...

10.1002/cjoc.202401146 article EN Chinese Journal of Chemistry 2025-02-24

The development of green protocols for photocatalysis where water acts as a nucleophile, induced by weak organic base, is difficult to achieve in chemistry. Herein, an efficient light-mediated strategy the synthesis amides which base reductant induce formation OH- from under metal-free conditions reported. A mechanistic study reveals that generation N,N-diisopropylethylamine (DIPEA) radical via single electron transfer (SET), with assistance photocatalyst, increases nucleophilicity molecules...

10.1039/d2ra02107b article EN cc-by-nc RSC Advances 2022-01-01

Abstract An ideal carrier that delivers small interfering RNA (siRNA) should be designed based on two criteria: high gene transfection efficiency and low cytotoxicity. In this work, arginine was used to modify polyvinylamine (PVAm) form a novel PVAm derivative (PVAm‐Arg) for siRNA delivery the characterized using Fourier transform infrared spectroscopy. PVAm‐Arg/siRNA complexes were formed by self‐assembly method. The zeta potential size of measured electrophoretic light scattering dynamic...

10.1002/pi.6386 article EN Polymer International 2022-03-03
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