A5081849348- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Adipose Tissue and Metabolism
- Meat and Animal Product Quality
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Fatty Acid Research and Health
- Effects of Environmental Stressors on Livestock
- Rangeland Management and Livestock Ecology
- Bee Products Chemical Analysis
- Muscle metabolism and nutrition
- Molecular Biology Techniques and Applications
- Carcinogens and Genotoxicity Assessment
- Cardiomyopathy and Myosin Studies
- Cancer Cells and Metastasis
- Mycotoxins in Agriculture and Food
- Osteoarthritis Treatment and Mechanisms
- Collagen: Extraction and Characterization
- Muscle Physiology and Disorders
- Animal Diversity and Health Studies
Inner Mongolia University
2024-2025
Inner Mongolia Agricultural University
2020-2025
Sheep are an important livestock species whose gastrointestinal tract is essential for overall health. Feed contaminants such as bacterial toxins and mycotoxins severely damage the sheep intestine, yet mechanisms remain mostly elusive partially due to lack of physiologically relevant in vitro models. Here, we investigated molecular underlying deoxynivalenol (DON)-induced toxicity by developing intestinal organoids from isolated crypts Hu sheep. The had a central lumen monolayer epithelium,...
This study aimed to elucidate the lipid composition, characteristics, and metabolic mechanisms of subcutaneous adipose tissue (SAT) in natural grazing Mongolian cattle during its development. The experimental animals consisted castrated cattle, divided into two groups: 10 months old (10 M, n = 12, average weight: 113.26 ± 0.87 kg) 34 (34 390.44 1.23 kg). All were selected from same herd Eren Nur grasslands, Xilingol, Inner Mongolia, China. Browning-related genes SAT determined using...
Adipose tissue metabolism plays a crucial role in sheep meat quality and the optimization of adipose utilization. To reveal molecular mechanisms during growth naturally grazing sheep, we investigated mRNA miRNA profiles subcutaneous (SAT) from Sunit at 6, 18, 30 months age (Mth-6, Mth-18, Mth-30). We identified 927 differentially expressed (DE) genes 134 DE miRNAs SAT different stages. Specifically, expressions ACACA, FASN, DGAT2, GPAM, SCD, ELOVL6, HSD17B12, TECR, PKM, TKT, PCK1, CD44,...
Intramuscular connective tissue (IMCT) collagen is an important factor in meat quality. This study analyzed the characteristics of type I and III IMCT semitendinosus (SD) longissimus dorsi (LD) Wuzhumuqin sheep at different growth stages (6, 9, 12, 18 months). Utilizing sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) Fourier transform infrared spectroscopy (FTIR), types were successfully isolated shown to contain intact triple helix structure. Immunofluorescence revealed...
Abstract The tail fat of sheep is the most typical deposited fat, and it can be widely used in human daily life, such as diet, cosmetics, industrial raw materials. To understand potential regulatory mechanism different growth stages Sunite sheep, we performed high‐throughput RNA sequencing to characterize long noncoding (lncRNA) messenger (mRNA) expression profiles at age 6, 18, 30 months. A total 223 differentially expressed genes (DEGs) 148 lncRNAs were found 6‐, 18‐, 30‐month‐old sheep....
Adipose tissue is a crucial economically significant trait that significantly influences the meat quality and growth performance of domestic animals. To reveal changes in adipose metabolism during naturally grazing sheep, we evaluated thickness, adipocyte morphology, fatty acid profile, metabolite profile subcutaneous (SAT) from Sunit sheep at 6, 18, 30 months age (referred to as Mth-6, Mth-18, Mth-30, respectively). The fat thickness number were increased with (p < 0.05), increase which...
MicroRNAs (miRNAs) are regarded as important regulators in skeletal muscle development. To reveal the regulatory roles of miRNAs and their target mRNAs underlying development Wuranke sheep, we investigated miRNA mRNA expression profiles biceps femoris these sheep at fetal (3 months gestation) 3- 15-month-old postnatal stages. Consequently, a total 1195 24,959 genes were identified. Furthermore, 474, 461, 54 differentially expressed (DEMs) 6783, 7407, 78 (DEGs) detected among three...
As the most typical deposited fat, tail fat is an important energy reservoir for sheep adapted to harsh environments and plays role as a raw material in daily life. However, regulatory mechanisms of microRNA (miRNA) circular RNA (circRNA) development remain unclear. In this study, we characterized miRNA circRNA expression profiles at ages 6, 18, 30 months. We identified 219 differentially expressed (DE) miRNAs (including 12 novel miRNAs), which exhibited major tendency be downregulated, 198...
Abstract Background: Sunite sheep are a fat-tailed species with low percentage of intramuscular fat and good quality lean meat, their tail can be used as source dietary by humans. To understand the potential regulatory mechanism different growth stages in sheep, we performed high-throughput RNA sequencing to characterize long noncoding (lncRNA) messenger (mRNA) expression profiles at age 6 months, 18 30 months. Results: A total 223 differentially expressed genes (DEGs) 148 lncRNAs were found...
Abstract The taste and tenderness of meat are the main determinants carcass quality in many countries. This study aimed to discuss mechanisms intramuscular fat deposition grazing house-breeding cattle. We performed transcriptome analysis characterize messenger RNA microRNA (miRNA) expression profiles. A total 456 66 differentially expressed genes (DEGs) (DE) miRNAs were identified adipose tissue Kyoto Encyclopedia Genes Genomes pathway association DEGs with fatty acid metabolism,...
Abstract Alxa Bactrian camel meat is an organic diet that provides balanced nutrition and easy to digest absorb. Despite its potential, it currently underutilized. To develop a new type of jerky, this study utilized single‐factor design method optimize the formula fermentation process parameters jerky. Additionally, physical chemical composition, nutritional components, protein degradation, microbial changes jerky were analyzed evaluate benefits created using modern technology. The results...
The color of carcass fat is an important factor in meat quality. To investigate the characteristics and changes lipid metabolism SAT Mongolian cattle at 34 M age compared with control group, we evaluated color, relative expression genes associated browning, profiles metabolites by using qPCR non-targeted lipidomics techniques. Overall, yellowness value mitochondrial biogenesis–specific markers, thermogenic, UCP2, beige adipocyte marker were higher than those (p &amp;lt; 0.05). Using...