- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Antibiotic Resistance in Bacteria
- COVID-19 Pandemic Impacts
- Vibrio bacteria research studies
- Chronic Lymphocytic Leukemia Research
- Antimicrobial Resistance in Staphylococcus
- Tuberculosis Research and Epidemiology
- Diverse Scientific Research Studies
- COVID-19 and Mental Health
- Bacterial Identification and Susceptibility Testing
- Disaster Response and Management
- Pneumonia and Respiratory Infections
- Chronic Myeloid Leukemia Treatments
- Acute Lymphoblastic Leukemia research
- Child Nutrition and Water Access
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Respiratory viral infections research
- COVID-19 diagnosis using AI
- COVID-19 Clinical Research Studies
- Ear Surgery and Otitis Media
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
Patan Hospital
2017-2023
Tribhuvan University Teaching Hospital
2023
Patan Academy of Health Sciences
2017-2023
Nepal Health Research Council
2023
B.P. Koirala Institute of Health Sciences
2014-2023
Dhulikhel Hospital
2017
Kathmandu University
2017
Introduction: Nepal started the first phase of COVID-19 vaccination for frontline healthcare workers in January 2021 with ChAdOx1 nCoV-19 (COVISHIELD) vaccine. We conducted active surveillance Adverse Effect Following Immunization (AEFI) after dose vaccine administered at one sentinel sites vaccination, Patan Academy Health Sciences (PAHS).
 Method: All 5591 ‘COVISHIELD’ recipients between 27 Jan -5 Feb PAHS, were approached through phone calls to collect data on AEFI. Incidence common...
Introduction: The rising incidence of antibiotic resistance is a global threat. Monitoring use one the strategies to address this issue. Intensive Care Units (ICUs) have high prevalence and multidrug-resistant organisms. This study aims status usage within ICU in tertiary care center. Methods: An observational cross-section was conducted from July 15, 2021 December 20, adult record section hospital Nepal after approval Institutional Review Committee. Data were collected medical records...
Abstract Background In Nepal, cases of Cholera occur annually either as sporadic or outbreaks claiming the lives many in rural areas. The present study is a laboratory based surveillance which aims to analyze changing epidemiology and antimicrobial susceptibility trend V. cholerae strains isolated referred National Public Health Laboratory (NPHL) over period 11 years (2006–2016). Methods Specimens fresh stool /rectal swab received at sentinel sites NPHL were processed following standard...
Patan Academy of Health Sciences started preparedness for COVID-19 in response to increasing number patient neighboring country. Outbreak resource limited setup is challenging. Despite this, was done reference WHO interim guidance utilizing best available resources. During this preparedness, one isolated as suspected COVID-19. This paper presents level achieved with the resources and lesson learned while isolating patient.Keywords: COVID-19; Disaster; hospital
Elizabethkingia anophelis, a gram-negative bacillus belonging to the Flavobacteriaceae family, is found in various environmental sources and has been associated with community hospital outbreaks. Correct identification crucial, guided by advanced genomic techniques, i.e., matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) system an updated database. The case fatality rate, ranging from 24 60%, underscores need for timely recognition appropriate...
Patan Hospital, Lalitpur, Nepal.To describe 1) the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) and its antibiotic sensitivity pattern; 2) demographic clinical characteristics associated with MRSA infections; 3) treatment outcomes in-patients infection among patients S. between January 2018 December 2020.This was a cross-sectional study using electronic paper-based hospital records infection.Of 1,804 infection, 1,027 (57%, 95% CI 55-59) had MRSA. The were susceptible to...
In times of disaster, hospital’s preparedness for disaster and response plan contributes significantly to better functioning the hospital reducing mortality morbidity. Activating Hospital incident command system in a timely manner Patan has showed how is prepared handle this epidemic outbreak.
Introduction: With the current COVID-19 pandemic, Patan Hospital, Academy of Health Sciences (PAHS), is responding with its incident action plan which also has provision response in case surge. This study aim to find out willingness doctors work during surge and may help further planning.
 Method: A cross-sectional descriptive was conducted at PAHS, Nepal April 2020. Questionnaires were circulated via Google form working emergency medicine department. Ethical approval obtained. Data...
Antimicrobial resistance (AMR) is a global problem, and Nepal no exception. Countries are expected to report annually the World Health Organization on their AMR surveillance progress through Global Resistance Surveillance System, in which enrolled 2017. We assessed quality of data during 2019–2020 at nine sites Province 3 for completeness, consistency, timeliness examined barriers non-reporting sites. Here, we present results this cross-sectional descriptive study secondary from five...
Introduction: Coronavirus disease 2019 (COVID-19) is an infectious caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and presents with fever, dry cough, fatigue, myalgia, dyspnea. This study aims to find out the understanding of COVID-19 among doctors at Patan Hospital. Method: A cross sectional was conducted Hospital, Academy Health Sciences, Nepal. The questionnaire in Google form consisted, part1 perception on part2 using multiple choice questions corresponding one...
Introduction: Various types of COVID 19 vaccine are being used globally to control the current pandemic. Post-licensure surveillance is essential ensure safety. This study aimed determine Adverse Events Following Immunization (AEFIs) China Sinopharm (Vero cell), inactivated COVID-19 vaccine.
 Method: a cross sectional observational conducted at Patan hospital, Academy Health Sciences (PAHS) after approval from IRC. Vaccine recipient between April 7 13 and May 16 25 were contacted...
The Glivec International Patient Assistance Programme makes (Imatinib mesylate) available to Philadelphia chromosome/BCR-ABL1 positive patients with chronic myeloid leukaemia (CML) in Lower and Middle Income Countries (LMIC). We have established a large cohort of 211 CML who are eligible for Imatinib, Kathmandu, Nepal. Thirty-one were lost follow-up. report on 180 median age 38 years (range 9–81). Of these patients, 162 underwent cytogenetic testing 110 investigated by reverse transcription...
Background: Hearing loss is a major health problem in developing country including Nepal.The prevalence of disabling hearing greatest South Asia followed by Pacific and Sub-Saharan Africa.World Health Organization estimates that affects over 360 million people worldwide. Objective:To analyze the pattern among patients attending Otorhinolaryngology outpatient department.Methods: This retrospective review data retrieved from record Pure Tone Audiomtery (PTA) results Department Dhulikhel...
Introduction: Methicillin resistant Staphylococcus aureus (MRSA) is one of the leading causes healthcare associated infection. It different types difficult-to-treat infections as these pathogens are to β-lactam antibiotics. The changing epidemiology, ever-increasing prevalence and trends susceptible antibiotics a global concern. aim this study was evaluate MRSA isolated from various samples. Method: hospital based descriptive cross-sectional conducted at Patan Hospital, Academy Health...
Introduction: Prevalence of multi and extensively drug resistant (MDR XDR) gram negative bacteria (GNB) are increasing trend becoming a threat to public health. There is no single effective antibiotic treat these pathogens. These superbugs need continuous surveillance develop relevant treatment protocols early therapeutic approaches. In this study, we evaluated the trends in prevalence, etiology antibiogram MDR XDR GNB isolated from various samples tertiary care hospital. Method: It was...
Infection prevention and control (IPC) programs play an integral part in the safety of patients, visitors, health care workers environment as these provide guidelines standard for recognition, infection. With COVID-19 pandemic, Patan Hospital, Academy Health Sciences, Nepal, is amongst few hospitals Nepal to have undertaken responsibility managing COVID patients. The response plan has been activated currently best prepared institution manage this pandemic.
Introduction: Diarrhea is the passage of three or more loose liquid stools per day more. Acute watery diarrhea a major public health problem worldwide. In Nepal, among top 10 inpatient morbidity. This study’s objective to monitor demographic characteristics and laboratory findings stool specimens diarrhea. Method: cross-sectional descriptive study done at Patan Hospital. Ethical approval was taken from committee. Data for Monsoon 2022 (June September 2022) were collected Hospital record...
Reduction in detection of asymptomatic carriage Haemophilus influenzae type b (Hib) can be used to assess vaccine impact. In Nepal, routine vaccination against Hib children at 6, 10, and 14 weeks age was introduced 2009. Before introduction, estimated 5.0% among aged <13 years with higher rates under 5. Large-scale evaluation has not been investigated since the introduction pentavalent diphtheria-tetanus-pertussis/Hib/hepatitis B (DTP-Hib-HepB) Nepal.A total 666 oropharyngeal swabs were...
Introduction: CD4 and CD8 T cells facilitate the containment of tuberculosis (TB) has been postulated that there will be changes in their level patients with TB. This study was carried out to analyze cell counts pulmonary (PTB) reference HIV status.Methods: A cross-sectional conducted at Department Microbiology a tertiary care hospital eastern Nepal from May 2012 April 2013. total 160 individuals, 40 each PTB, PTB/HIV, healthy population were included after obtaining informed consent. PTB...
Background: CD4 and CD8 T cells facilitate the containment of tuberculosis (TB) has been postulated that there will be changes in their level patients with TB. So this study was carried out to analyse cell counts pulmonary (PTB) reference HIV status determine relation between severity PTB count. Methods & Materials: A cross-sectional conducted at laboratory, Department Microbiology from May 2012 April 2013 approved by IERB, BPKIHS. total 160 individuals, 40 each PTB, PTB/HIV, healthy...
An operational research study was conducted in 2019 to assess the quality of data submitted by antimicrobial resistance (AMR) surveillance sites Bagmati Province Nepal National Public Health Laboratory for Global Antimicrobial Resistance and Use Surveillance System (GLASS). Measures were implemented enhance AMR strengthening capacity, improving infrastructure, implementing sharing guidelines, supervision. The current examined reports same province 2022 whether had improved since 2019....
Introduction: Pfizer-BioNTec vaccine was started in Nepal for the age group of more than 12 y. This study conducted to find out adverse event following immunization with Pfizer-BioNTech against COVID-19 at Patan Academy Health Sciences (PAHS). Method: is a descriptive PAHS from November December 2021. The recipients were called over phone after 72 h receiving events (AEFI). They inquired about list pre-defined AEFI. Ethical approval obtained. Result: A total 1377(27.4%) individuals among...