A5046943476- Laser-Matter Interactions and Applications
- Quantum optics and atomic interactions
- Photorefractive and Nonlinear Optics
- Laser Design and Applications
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Sustainable Industrial Ecology
- Solid State Laser Technologies
- Quantum Information and Cryptography
- Optical and Acousto-Optic Technologies
- Atomic and Molecular Physics
- Cold Atom Physics and Bose-Einstein Condensates
- Sustainable Supply Chain Management
- Semiconductor Lasers and Optical Devices
- Environmental Impact and Sustainability
- Advanced X-ray Imaging Techniques
- Laser-Plasma Interactions and Diagnostics
- Spectroscopy and Laser Applications
- Laser-induced spectroscopy and plasma
- Mechanical and Optical Resonators
- Diamond and Carbon-based Materials Research
- Chemistry and Chemical Engineering
- Bone Metabolism and Diseases
- Quantum Mechanics and Applications
- Atomic and Subatomic Physics Research
Stanford University
2007-2024
The Royal Wolverhampton NHS Trust
2020-2024
King's College Hospital
2022
IVL Swedish Environmental Research Institute
2018-2022
Mental Research Institute
2021
IVL Swedish Environmental Research Institute
2020-2021
San Francisco State University
2018
Lund University
2014
Norwegian Institute for Sustainability Research
2014
Chalmers University of Technology
2013
Osteoporosis and other diseases of bone loss are a major public health problem. Here it is shown that the statins, drugs widely used for lowering serum cholesterol, also enhance new formation in vitro rodents. This effect was associated with increased expression morphogenetic protein–2 ( BMP-2 ) gene cells. Lovastatin simvastatin when injected subcutaneously over calvaria mice cancellous volume orally administered to rats. Thus, appropriate doses, statins may have therapeutic applications...
This paper reviews progress on tunable optical parametric oscillators. Topics considered include: amplification of Gaussian beams: threshold; tuning techniques, spectral output, and stability; saturation power output; spontaneous emission; nonlinear materials; far infrared generation.
This paper proposes a new type of electronically tunable optical filter. The basic idea is to utilize collinear acousto-optic diffraction in an optically anisotropic media. Changing the driving acoustic frequency changes band frequencies that filter passes. A LiNbO3 with pass approximately 1.3 cm−1 wide should be from 4000 7000 Å by changing 428 990 Mc/sec. For this case, angular aperture will about 1.5°, and, theoretically 100% transmittance attained at center use 14 mW power per mm2 aperture.
The Circular Economy (CE) concept is receiving increasing global attention and has captivated many disciplines, from sustainability through to business economics. There currently a strong drive by companies, academics governments alike implement the CE. Numerous "circularity indicators" have emerged that measure material flow or recirculated value of system (e.g. product nation). However, if its implementation improve environmental performance society, action must be based on scientific...
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We report the observation of a gain approximately $\mathrm{exp}\left(11\right)$ at 41.8 nm in 8-times-ionized xenon. This extreme ultraviolet (XUV) laser is driven by 10-Hz, 70-mJ circularly polarized femtosecond pulse. The focused into Xe pressures ranging from 5 to 12 torr. collisionally excited, with both ions and electrons produced field induced tunneling.
We have found that the ubiquitin-proteasome pathway exerts exquisite control of osteoblast differentiation and bone formation in vitro vivo rodents. Structurally different inhibitors bind to specific catalytic beta subunits 20S proteasome stimulated organ cultures concentrations as low 10 nM. When administered systemically mice, epoxomicin inhibitor-1 increased volume rates over 70% after only 5 days treatment. Since has been shown modulate expression Drosophila homologue morphogenetic...
This Letter describes the generation of biphotons with a temporal length that can be varied over range 50-900 ns, an estimated subnatural linewidth as small 0.75 MHz. We make use electromagnetically induced transparency and slow light in two-dimensional magneto-optical trap optical depth high 62. report sharp leading edge spike is Sommerfeld-Brillouin precursor, observed at biphoton level.
Theoretical and experimental results concerned with the spectral angular distribution of spontaneous parametric emission are reported. Such when light from a pumping laser is incident on nonlinear crystal, does not require that gain exceed single-pass crystal loss. The somewhat like Raman or Brillouin scattering, but differs in two major respects. First, lossless bandwidth controlled by length accepted aperture as opposed to loss mechanism case. Second, changing temperature orientation, may...
We report clear experimental evidence for second harmonic generation at hard x-ray wavelengths. Using a 1.7 Å pumping beam generated by free electron laser, we observe in diamond. The is of order 10 times the background radiation, scales quadratically with pump pulse energy, and over narrow phase-matching condition. Of importance future experiments, our results indicate that it possible to nonlinear processes crystals intensities exceeding 1016 W/cm2.
A procedure for the synthesis of birefringent networks having arbitrarily prescribed transfer functions is presented. The basic network configuration consists n identical cascaded crystals between an input and output polarizer. are cut with their optic axes perpendicular to length. variables determined by angles angle Any function which periodic frequency whose corresponding impulse response real causal can, in theory, be realized. allows approximation a desired (n+1) terms Fourier...
The circular economy is billed as a solution to increase economic growth while reducing environmental impact. It argued that retaining the value of products, components and materials by fostering "inner loops", such reuse, refurbishment remanufacturing, increases resource-efficiency. However, published assessments estimating actual impact these so-called outcomes are inconclusive. This paper presents results systematic literature review previous on products business models, focusing tighter...
Using intense lasers, several laboratories have generated high-order harmonic spectra which are flat over 20 eV. If the harmonics appropriately phased, this bandwidth corresponds to temporal pulses on order of ∼ 5 × 10-17 s, and thereby motivates a search for new regime short-pulse generation.
Abstract In addition to structural proteins of bone, such as type I collagen, bone cells synthesize a number growth regulatory peptides that are also stored in the matrix, presumably consequence local production by osteoblasts. Among found matrix recently described morphogenetic (BMPs). These factors were purified from their capacity stimulate ectopic formation, but it is not known whether they produced normal and influence formation. To determine expressed osteoblasts during...
We discuss the effect of transient response on dynamics lifetime broadened lasers that operate without need for population inversion. A relationship between steady-state absorptive transition probability rate and gain loss is given.
A dye laser which is electronically tunable over 780 Å has been obtained by inserting a CaMoO4 acousto-optic filter into the dye-laser cavity. half-power linewidth of 6.8 yields 1.35 Å. Oscillation at two simultaneous independently wavelengths and variable output coupling observed.
We report the generation of 1773-, 1520-, and 1182-\AA{} radiation by frequency tripling summing in a phase-matched mixture Cd Ar. For third-harmonic process, $5320\ensuremath{\rightarrow}1773$ \AA{} phase matching occurs for Ar atoms ratio 1: 25, ${\ensuremath{\chi}}^{(3)}\ensuremath{\cong}2\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}34}$ esu/atom. The energy conversion efficiency to 1773 was about ${10}^{\ensuremath{-}4}$, yielding peak picosecond power 7 kW.
We describe an optical process where off-diagonal excitation of a first atomic species is coupled during collision to second species. This coupling leads new types nonlinear processes, and allows large cross sections for inelastic between atoms with nonresonant energy levels.
We experimentally and theoretically study the coincidence count rate for down-converted x-ray photons. Because of photoionization, parametric down-conversion at wavelengths generally involves loss theoretical description requires a Langevin approach. By working in transmission geometry (Laue) rather than Bragg previous experiments, we obtain an improvement signal-to-noise ratio 12.5, find agreement between experiment theory.