A5016289949- Veterinary Medicine and Surgery
- Pediatric Urology and Nephrology Studies
- Cardiovascular Conditions and Treatments
- Veterinary Equine Medical Research
- Clinical Laboratory Practices and Quality Control
- Animal testing and alternatives
- Liver Disease Diagnosis and Treatment
- Nitric Oxide and Endothelin Effects
- Urological Disorders and Treatments
- Chronic Kidney Disease and Diabetes
- Vitamin C and Antioxidants Research
- Acute Kidney Injury Research
- Advanced Proteomics Techniques and Applications
- Hedgehog Signaling Pathway Studies
- Renal and Vascular Pathologies
- Urinary Tract Infections Management
- Body Composition Measurement Techniques
- Pregnancy and Medication Impact
- Lipid metabolism and disorders
- Prenatal Screening and Diagnostics
- Infant Nutrition and Health
- Polyamine Metabolism and Applications
- Stress Responses and Cortisol
- Hormonal Regulation and Hypertension
- Renal function and acid-base balance
University of Milan
2016-2022
Policlinico San Matteo Fondazione
1995
Objectives The aim of this study was to assess whether, in contrast serum creatinine, which is higher Birman cats than other breeds, the concentration symmetric dimethylarginine (SDMA) comparable clinically healthy Birmans and general feline population. This could allow, breed, better evaluate chronic kidney disease (CKD). Methods Serum creatinine SDMA were measured (n = 50) breeds 46), results statistically compared. A breed-specific reference interval (RI) established for compared with RI...
Antibiotic-responsive enteropathy (ARE) is diagnosed by excluding other causes of diarrhea and when there a short-term response to administration antibiotics.To characterize the gut microbiota clinical trend dogs with suspected ARE evaluate variation in before (T0), after 30 days (T30) tylosin treatment, discontinuation treatment (T60). A further objective was whether changes are related relapses therapy tapered.Study sample (group A) composed 15 chronic diarrhea, group B healthy dogs. Group...
Background Microscopic evaluation of urine is inconsistently performed in veterinary clinics. The IDEXX SediVue Dx® Urine Sediment Analyzer (SediVue) recently was introduced for automated analysis canine and feline may facilitate performance urinalyses practice. Objective Compare the with manual microscopy detecting clinically relevant numbers cells 2 crystal types. Samples Five‐hundred thirty samples (82% canine, 18% feline). Methods For (software versions [SW] 1.0.0.0 1.0.1.3),...
Background Several breeds have physiological peculiarities that induce variations in reference intervals (RIs) compared with the general canine population. Shetland sheepdogs ( SS s) are reported to be more predisposed different diseases (eg, hyperlipidemia, gallbladder mucocele, and hypothyroidism). Consequently, a breed‐specific approach is often required. Objectives The aim of this study was determine whether RI s population could applied s, generate where appropriate. Methods Sixty...
Proteinuria quantification with the urinary protein-to-creatinine (UPC) ratio is part of diagnostic process in feline patients suspected chronic kidney disease (CKD). In affected cats, monitoring and substaging UPC according to International Renal Interest Society (IRIS) guidelines also necessary for appropriate patient management. No information available about possible effects analytical variability on proteins (UPs) cats.This study aimed determine whether imprecision method-dependent...
To date, little information is available about the effect of preanalytical factors on urinary protein-to-creatinine (UPC) ratio in cats.We aimed to evaluate a commercially cat litter, creatinine measurements at three different dilutions urine, and storage conditions UPC cats.Feline urine specimens were prospectively collected. Twenty-two whole-urine placed uncovered contact with litter for 1 hour; 25 supernatants diluted 1:10, 1:20, 1:100 measurements. The correlation, difference, agreement,...
Background The dipstick is a first‐line and inexpensive test that can exclude the presence of proteinuria in dogs. However, no information available about analytical variability canine urine analysis. Objectives aim this study was to assess 2 dipsticks inter‐operator interpretation. Methods Canine supernatants ( n = 174) were analyzed with commercially dipsticks. Two observers evaluated each result blinded other observer results dipstick. Intra‐ inter‐assay assessed 5 samples (corresponding...
The purpose of this study was to describe the electrophoretic patterns proteinuria in cats at risk and with chronic kidney disease (CKD), investigate whether presence high-molecular-weight (HMW) low-molecular-weight (LMW) proteins were associated CKD, and/or progression.
Neuroglial choristomas are rare malformations consisting of heterotopic mature neural tissue at a site isolated from the brain or spinal cord. In human medicine, neuroglial predominantly reported in head and neck, except for one recent case foot child. domestic animals, exceedingly rare, only retina dog, pharynx skin two kittens, within oropharynx harbor seal. A three-year-old intact female Jack Russell Terrier presented elective ovariectomy exhibited cystic lesion 2 cm diameter expanding...
The endothelin-1 (ET-1) system has been implicated in the development and progression of chronic kidney disease (CKD). No information on big ET-1 feline urine is available. purpose this study was to evaluate if urinary (bigET-1) associated with CKD. Sixty samples were prospectively collected from 13 healthy cats at risk developing CKD 22 different International Renal Interest Society (IRIS) stages (1-4). Urinary bigET-1 measured using a commercially available ELISA. BigET-1 normalized...
Urinary alpha1-microglobulin (a1M) in people is a biomarker of renal tubular damage (Bazzi, 2001), but it has not yet been used cats with chronic kidney disease (CKD). The aim this study was to validate an ELISA test marketed for the measurement feline a1M. Thirty-four urine supernatants collected from affected by or at risk CKD were assayed SDSAGE, classify patients according presence absence low molecular weight proteinuria suggestive damage. Two samples and one without bands evaluate...
ABSTRACT Background Automated fluorescence‐based haematology analysers are now available for reticulocyte enumeration in veterinary medicine, but manual counting is still largely used. This study aimed to evaluate potential sources of analytical and pre‐analytical errors when performing automated counts. Methods two‐operator double‐blind counts were performed on 15 blood samples. The intra‐assay variation the interoperator then calculated. In addition, effects storage evaluated using samples...