- Mycobacterium research and diagnosis
- Veterinary Oncology Research
- Veterinary Medicine and Surgery
- Microbial infections and disease research
- melanin and skin pigmentation
- Aquaculture disease management and microbiota
- Bladder and Urothelial Cancer Treatments
- Congenital Anomalies and Fetal Surgery
- Identification and Quantification in Food
- Reproductive biology and impacts on aquatic species
- Fish Ecology and Management Studies
- Vector-borne infectious diseases
- Skin Protection and Aging
- Veterinary Orthopedics and Neurology
- Sperm and Testicular Function
- Virus-based gene therapy research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Bird parasitology and diseases
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Mycology
- Turtle Biology and Conservation
- Tumors and Oncological Cases
- Animal Behavior and Welfare Studies
- Bacteriophages and microbial interactions
- Mosquito-borne diseases and control
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"
2021-2024
University of Milan
2018-2021
In aquaculture, Lactococcus garvieae is a common fish pathogen that can cause significant economic losses in several fresh and saltwater species. Despite the extensive range of hosts, L. infection sea bass (Dicentrarchus labrax) has rarely been reported. During summer 2023, an outbreak occurred inland farm Gulf Follonica (Tuscany, Italy). Fish various sizes were affected, showing apathy, inappetence, erratic swimming eye lesions, while mortality was low (2–3% per month). Anatomopathological...
Abstract Tick-borne encephalitis was limited to northeast portions of Italy. We report in Lombardy, a populous region the northwest, chamois displaying clinical signs tickborne virus that had multiple virus-positive ticks attached, as well symptomatic man. Further, we show serologic evidence viral circulation area.
Paratuberculosis (Johne’s disease) is a globally widespread infectious disease affecting domestic and wild ruminants, caused by Mycobacterium avium subsp. paratuberculosis (MAP). The bacterium excreted in the feces characterized high environmental resistance. new Animal Health Law (Regulation EU 2016/429) on transmissible animal diseases, recently force throughout European Union, includes within diseases requiring surveillance EU, listing some Bovidae, Cervidae, Camelidae as potential...
Abstract Aims Our study evaluates the capacity of direct real-time PCR for detecting Mycobacterium tuberculosis complex (MTBC), with a focus on diagnostic performances and feasibility implementing this protocol in an eradication campaign. Specifically, we compare effectiveness method to various culture systems used by Italian National Reference Laboratory over last decade detect MTBC. Methods results Bovine tissue samples were routinely tested analyzed bovine (bTB) confirmation using...
Skin spindle cell tumors (SSTs) frequently occur in fishes, with peripheral nerve sheath (PNSTs) being the most commonly reported neoplasms goldfish. However, distinguishing PNSTs from other SCTs is not always possible when relying exclusively on routine cytological and histopathological findings. Therefore, aim of this study to characterize six skin nodules, resembling atypical neurofibromas humans, found cohabiting goldfish (Carassius auratus), determine a minimal subset special stains...
The bladder urothelial carcinoma (UC) represents ~2% of malignant neoplasms in dogs and is a therapeutic challenge veterinary medicine. Although it considered the most common cancer dogs, few previous studies have investigated different markers that correlate with clinical pathological parameters. Therefore, this study aimed to evaluate Caveolin-1, GATA-3, Ki67 immunostaining canine UC samples their correlations histopathological variables. Thirty tumor were obtained, expression was assessed...
Abstract Koi( Cyprinus carpio ) is an ornamental variety of common carp frequently kept as pets. Given their long lifespan, neoplasia, albeit uncommon, may occur in these animals, and only a few studies have faced cytological diagnosis. In the present case, koi was referred to clinicians due coelomic swelling. The underwent surgery, which revealed enlargement both testes. Testicular samples were cytologically histologically examined. lesion diagnosed seminoma since it composed round, large,...
Urothelial carcinoma (UC), also known as transitional cell carcinoma, is the most common malignant tumor of canine urinary bladder and represents a model for studying human cancer. However, existing literature has limited data on clinicopathological characteristics these tumors their prognostic value.The aim this study was to evaluate such factors, correlating them with follow-up, in group 32 dogs UC.Clinical cases, submitted São Paulo State University VetPat Private Laboratory (São...
Abstract Koi carp ( Cyprinus carpio ) is an ornamental variety of common frequently kept as pets. Since their long lifespan, neoplasia, albeit rare, may occur in these animals, and only a few studies have faced cytological diagnosis. In the present case, koi was referred to clinicians due coelomic swelling. The underwent surgery, which revealed enlargement both removed testes. Testicular samples were cytologically histologically examined. lesion diagnosed seminoma since it composed round,...
In fluorescence microscopy, light radiation can be used to bleach fluorescent molecules in formalin-fixed and paraffin-embedded (FFPE) samples, order increase the ratio between signal of interest background autofluorescence. We tested if same principle exploited bright field microscopy pigmented melanoma FFPE sections together with cell morphology maintenance. After dewaxing rehydration, serial a feline diffuse iris melanoma, canine dermal gray horse swine cutaneous were irradiated visible...
Paratuberculosis, a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (MAP), in ten scimitar-horned oryxes (SHOs) hosted an Italian zoological park and originating from Slovakian flock, was documented pathology, molecular, cultural, serological testing. The infection origin this threatened species also investigated genomic analyses. Following the death of six 10 SHOs, serial investigations dead alive animals were performed. Necropsy, carried out on five animals,...
The description of the unique cytological features a skin lesion in an old dog affected with leishmaniasis is here reported. In nodular on metacarpus coexistence histiocytic cells suggestive histiocytoma and Leishmania spp. amastigotes, both background neoplastic cells, were found. A 10-year-old male Italian Volpino crossbreed was referred for second opinion not-responsive anemia. had history travel across Europe, including Spain. month before, visited Canary Islands lethargy, dysorexia...
Neuroglial choristomas are rare malformations consisting of heterotopic mature neural tissue at a site isolated from the brain or spinal cord. In human medicine, neuroglial predominantly reported in head and neck, except for one recent case foot child. domestic animals, exceedingly rare, only retina dog, pharynx skin two kittens, within oropharynx harbor seal. A three-year-old intact female Jack Russell Terrier presented elective ovariectomy exhibited cystic lesion 2 cm diameter expanding...
Forty‑one tumors were detected in a population of 1,649,003 cattle slaughtered 4 abattoirs Lombardy over 5‑year period, for an overall prevalence 2.5 per 100,000 cattle. Tumors classified according to the WHO histological classification domestic animals. Alimentary and hemopoietic systems commonly affected with 9 cases each. Other sites respiratory (n = 3), urinary 2), endocrine musculoskeletal nervous 1), cardiovascular 1) systems. The peritoneum was by 6 cases, while primary location 3...
An 11-year-old female Hapalemur alaotrensis was evaluated following a history of dyspnea 15 days’ duration. Thoracic radiography performed by the referring veterinarian revealed large cardiac silhouette and dorsal deviation trachea. Heart sounds were muffled. Echocardiographic findings indicative severe pericardial effusion without tamponade. No pleural identified. A computed tomography (CT) exam confirmed presence allowed identification parenchymatous mediastinal lesion sited at level left...
Mycobacteria in cats are responsible for cutaneous or visceral disease, often with systemic involvement (Gunn-Moore et al., 2011). Infection can be sustained by tuberculous (e.g. M.bovis) and non-tuberculous mycobacteria M.avium M.lepraemurium) (Lee 2017). The aim of this study is to evaluate the distribution lesions feline mycobacteriosis.Twenty-nine necropsy cases mycobacteriosis, conferred from 1965 2017, were studied. On histopathology hematoxylin-eosin acid-fast stains performed....