Abstract To provide possible laboratory support to health risk evaluation associated with long‐term, low‐intensity magnetic field exposure, 256 male albino rats and an equal number of control animals (initial age 12 weeks) were exposed 22 h/day a 50 Hz flux density 5 μmT for 32 weeks (a total about 5000 h). Hematology was studied from blood samples before exposure the at week intervals. Morphology histology liver, heart, mesenteric lymph nodes, testes as well brain neurotransmitters assessed...

Perivascular wall tumors (PWTs) are defined as neoplasms deriving from mural cells of blood vessels, excluding the endothelial lining. The spectrum human cutaneous PWT includes glomus tumor, hemangiopericytoma (HEP), myopericytoma, angioleiomyoma/sarcoma, angiomyofibroblastoma, and angiofibroma. purpose this study was to revise clinical presentation, cytology, histopathology, immunohistology canine with cytology typical HEP. Diagnosis established on basis vascular growth patterns (staghorn,...

Abstract Objective —To determine factors predicting survival in dogs with high-grade multicentric lymphoma. Design —Retrospective cohort study. Animals —127 lymphoma evaluated at 4 veterinary hospitals from 2000 to 2009. Procedures —Records were reviewed identify completely staged treated chemotherapy. Data collected included signalment, history, hematologic findings, tumor characteristics, treatment, and outcome. Long-term was defined as surviving > 2 years after diagnosis. Variables...

In the clinical staging of cutaneous mast cell tumors (cMCT), diagnosis metastasis is controversial based on cytological examination lymph nodes, spleen, liver, bone marrow, and blood.To define prognostic role ultrasound-guided cytology spleen liver in cMCT. The results evaluation were compared relation with survival time.Fifty-two client-owned dogs a cMCT.Selection cases was to detect infiltration at distant sites. Kaplan Meier method used compare without (log-rank test P < .05).Ten cMCT...

Background: Fine‐needle aspiration cytology (FNAC) is commonly used as a diagnostic procedure to evaluate superficial and deep masses in animals. However, few studies have addressed the accuracy of FNAC evaluation cutaneous subcutaneous clinical setting. Objective: The purpose this study was compare compared with histopathology diagnosis from dogs cats. Methods: Cytologic histopathologic specimens obtained between 1999 2003 292 palpable 242 50 cats were retrospectively evaluated. samples by...

Clinicopathologic and immunophenotypic characteristics of large granular lymphocyte (LGL) neoplasia in 21 cats were examined. All domestic short (19) or long hair (2) with a mean age 9.3 years at diagnosis. Increased peripheral blood LGL counts present 18/21 cats. Neutrophilia (12/21 cats) increased serum liver enzymes (7/12), total direct bilirubin (7/13), BUN (5/14), creatinine (2/14) observed. Cats usually presented advanced disease none survived longer than 84 days (mean 18.8 days)...

Cytospin preparations of fine-needle aspirates from 21 dogs with peripheral lymphadenopathy (18 lymphoma and three lymph node hyperplasia) were studied by combining morphologic immunocytochemical analysis. Fine-needle taken at least two enlarged nodes, the diagnosis was based on air-dried smears stained May-Grünwald Giemsa. aspiration biopsy always provided an adequate quality quantity cells to perform immunologic studies. Immunophenotyping performed cytospin a panel eight monoclonal...

Abstract Background The therapeutic role and prognostic relevance of lymphadenectomy in mast cell tumor (MCT) has historically been evaluated on regional rather than sentinel lymph nodes. Hypothesis/Objectives To update information about the association histological nodal (HN) classes with clinical outcome dogs MCT after excision extirpation normal‐sized nodes (SLN) guided by radiopharmaceutical. Animals Ninety‐four histologically‐confirmed treatment‐ naïve (71 cutaneous, 22 subcutaneous 1...

Angiosarcomas (AS) are malignant tumors that arise from vascular endothelial cells and common in dogs. Histologically, AS markedly heterogeneous neoplasms make interpretation by cytology difficult.Our objective was to evaluate the cytologic features of canine look for additional diagnostic criteria.Cytologic specimens 19 histologically immunohistochemically confirmed cases were extensively reviewed features. We compared cytologic, histopathologic, immunohistochemical findings.Neoplastic 14...

Lymphoma is the most common feline upper respiratory tract (URT) tumor. Primary nasal and nasopharyngeal lymphomas have been evaluated as distinct pathological entities; however, data on their differing clinical behavior are missing. A total of 164 endoscopic- guided URT pinch biopsies were formalin fixed routinely processed. Imprint cytological specimens stained with May Grünwald-Giemsa. Immunohistochemistry for anti-CD20, CD3, FeLVp27, FeLVgp70 was performed. Prognostic significance...

Cell blocks are widely used in human cytopathology. Several techniques have been proposed to convert fluid specimens into solid material, which after embedding paraffin can be for histochemistry, immunohistochemistry, or molecular testing. In contrast, only the last few years, cell begun veterinary field.The purpose of study was present production and features tube (CTB) with liquid samples.Liquid samples including cerebrospinal fluid, cutaneous cyst pericardial pleural effusions,...

The aim of this study was to evaluate the effects addition two roughage sources (wheat straw and beet pulp) milk replacer diet veal calves, in order reduce stress improve animal welfare. We allocated 138 Polish Friesian male calves three different feeding plans: a (Control), 250 g/d wheat replacer, or dried pulp replacer. Within each treatment, 16 were individually housed 30 kept group pens (five calves/pen). Several behavioral, physiological, health welfare indicators monitored throughout...

The cytological features of 19 histologically confirmed canine ovarian tumours were retrospectively examined. Seven cases cytologically classified as papillary adenocarcinoma, eight granulosa cell tumours, two mature teratomas, one case a dysgerminoma and mixed tumour/dysgerminoma. On cytology, adenocarcinoma was characterised by glandular pattern tight cohesiveness. Granulosa showed monolayered clusters loosely cohesive cells. Call-Exner-like bodies found in five seven cases. cells appeared...

Feline primary cutaneous lymphomas (FPCLs) account for 0.2% to 3% of all in cats and are more frequently dermal nonepitheliotropic small T-cell tumors. Emergence FPCL seems unrelated feline leukemia virus (FeLV) serological positivity or skin inflammation. A total 17 with a history vaccine injection at the site tumor development were selected from 47 FPCLs. Clinical presentation, histology, immunophenotype, FeLV p27 gp70 expression, clonality assessed. majority male (12/17), domestic...

Groups of adult male Sprague Dawley rats (64 each) were exposed for 8 months to electromagnetic fields (EMF) two different field strength combinations: 5μT - 1kV/m and 100μT 5kV/m. A third group was sham exposed. Field exposure hrs/day 5 days/week. Blood samples collected hematology determinations before the onset at 12 week intervals. At sacrifice, liver, heart, mesenteric lymph nodes, bone marrow, testes morphology histology assessments, while pineal gland brain biochemical determinations....

Splenic marginal zone lymphomas (MZL) in dogs arise from the of B-cell follicles and can progress slowly.To describe clinical features, treatment, outcome with splenic MZL.Five naturally occurring MZL.Clinical, laboratory, follow-up data were retrospectively reviewed. Diagnosis was based on clinical, histopathological, immunophenotypic features.All had stage IV disease; among them, 2 symptomatic (substage "b") because rupture. Four underwent splenectomy adjuvant doxorubicin, 1 dog surgery...

Abstract Background While lymphadenectomy of metastatic lymph nodes (LNs) has been associated with improved outcome, the clinical utility prophylactic in dogs stage I cutaneous mast cell tumors (cMCTs) remains a controversial topic. To assess therapeutic role uninvolved regional LNs, long-term outcome cMCT-bearing cytologically negative and surgically unresected LNs (observation only, OO) was compared that resected histologically (prophylactic lymphadenectomy, PRL). Results A retrospective...

Feline Progressive Histiocytosis (FPH) is a cutaneous dendritic cell neoplasm characterized by slow progression and spread to internal organs in the terminal stage. FPH often misdiagnosed as an inflammatory reaction has not been fully from cytologic diagnostic perspective.The purpose of study was characterize immunocytochemical aspects useful for diagnosis.Fine-needle aspiration samples 5 cases confirmed skin biopsy necropsy were evaluated. Immunocytochemistry with antibodies recognizing...

Cytology represents a useful diagnostic tool in the preliminary clinical approach to canine splenic lesions, and may prevent unnecessary splenectomy. However, few studies have evaluated accuracy of cytology diagnosis neoplasms. The aim this study was determine overall accuracy, sensitivity, specificity, positive negative predictive values (i.e. indexes) for neoplasms following Standards Reporting Diagnostic Accuracy Studies (STARD) guidelines. A consecutive series cytological samples...

Multiple endocrine neoplasia (MEN) embodies a group of diseases in human patients and domestic animals that are characterized by hyperplasia or neoplasia, both, two more tissues. The MEN-1 syndrome is associated with menin gene mutations induce various combinations parathyroid, pituitary, pancreatic tumors humans. Two male, Domestic Shorthair cats developed symmetric alopecia, insulin-resistant diabetes mellitus, pituitary-dependent hyperadrenocorticism at 12 13 years age. Examination skin...