- Veterinary Oncology Research
- Infectious Diseases and Mycology
- Microbial infections and disease research
- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Veterinary Medicine and Surgery
- Salivary Gland Tumors Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Tumors and Oncological Cases
- Reproductive Physiology in Livestock
- Hepatocellular Carcinoma Treatment and Prognosis
- Bird parasitology and diseases
- Testicular diseases and treatments
- Mast cells and histamine
- Reproductive Biology and Fertility
- Pediatric Hepatobiliary Diseases and Treatments
- Toxin Mechanisms and Immunotoxins
- Asthma and respiratory diseases
- Cancer and Skin Lesions
- Gallbladder and Bile Duct Disorders
- Cystic Fibrosis Research Advances
- Nail Diseases and Treatments
- Trypanosoma species research and implications
- Insects and Parasite Interactions
- Hedgehog Signaling Pathway Studies
Veterinary Oncological Center
2005-2022
Laboratori Guglielmo Marconi (Italy)
2009-2016
University of Brescia
2004-2016
Ab Analitica (Italy)
2008
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"
2006
University of Perugia
2006
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Gran Sasso
2005-2006
University of Bologna
2006
Ospedale Civile di Voghera
2005
Angiosarcomas (AS) are malignant tumors that arise from vascular endothelial cells and common in dogs. Histologically, AS markedly heterogeneous neoplasms make interpretation by cytology difficult.Our objective was to evaluate the cytologic features of canine look for additional diagnostic criteria.Cytologic specimens 19 histologically immunohistochemically confirmed cases were extensively reviewed features. We compared cytologic, histopathologic, immunohistochemical findings.Neoplastic 14...
To compare the efficacy and diagnostic value of four different sample collection techniques for cytological identification nasal aspergillosis-penicilliosis in dogs.Fifteen dogs with a history persistent discharge clinical radiographic findings suggestive aspergillosis were evaluated using sampling techniques. These direct smear from discharge, blind swab under general anaesthesia, brushing suspect lesions endoscopic visualisation squash technique mucosal biopsies obtained...
The cytological features of 19 histologically confirmed canine ovarian tumours were retrospectively examined. Seven cases cytologically classified as papillary adenocarcinoma, eight granulosa cell tumours, two mature teratomas, one case a dysgerminoma and mixed tumour/dysgerminoma. On cytology, adenocarcinoma was characterised by glandular pattern tight cohesiveness. Granulosa showed monolayered clusters loosely cohesive cells. Call-Exner-like bodies found in five seven cases. cells appeared...
To determine results of cytologic examination fine-needle aspirates and impression smears gastrointestinal tract tumors in dogs cats.Retrospective case series.38 44 cats with histologically confirmed tumors.Results (n = 67) or (31) were compared the histologic diagnosis, extent agreement was classified as complete, partial, none, undetermined.For 48 67 (72%) aspirates, there complete partial between diagnoses. For 12 (18%) could not be determined because specimen considered unsatisfactory....
Cytologic diagnosis of hepatocellular carcinoma is possible when hepatocytes have prominent criteria malignancy, but problematic a relatively normal morphologic appearance.The aim this study was to determine the cytologic features histologically confirmed well-differentiated carcinomas (WD-HCC) in dogs develop reasonable for an accurate obvious malignancy are lacking.Slides ultrasound-guided fine-needle aspirates 15 WD-HCC were evaluated retrospectively using scoring system (0-3) established...
Summary In this paper, we report on our experience of cytology fine needle biopsies performed 92 dogs with testicular tumours during the period from 1998 to 2002. Cytological diagnosis was consistent seminoma in 20 cases, sertolioma 16 Leydig cell 50 cases and mastocytoma one case. Five could not be diagnosed by cytology. observations were confirmed after surgery histopathological examination 87 cases. Cytology provided a sensitivity 95% for seminoma, 88% 96% tumours. The specificity 100%...
Background: The cytologic diagnosis of ear canal tumors is difficult or impossible by swab alone because cell exfoliation may be poor and neoplastic cells masked associated inflammation. Fine‐needle biopsy (FNB) can used to obtain a higher yield for diagnosis. Objectives: purpose this study was assess the efficacy diagnostic value FNB examination in providing an accurate masses growing external cats. Methods: Cytologic specimens from canal, taken under inhaled, general anesthesia, were...
Oil Red O, a stain commonly used to demonstrate lipid in frozen tissue, also may be air-dried cytologic specimens.The purpose of this study was prospectively evaluate the value O identifying aid differentiation liposarcomas from other types sarcoma.Twelve tumor specimens dogs were evaluated. The tumors included if initial evaluation indicated sarcoma, and histologic confirmation available. applied all specimens.Tumor diagnosed histologically as liposarcoma (3 well-differentiated, 1...
Cellular arrangements are highly relevant in the evaluation of histologic sections, but cytologic specimens not thought to accurately reflect same patterns. Only occasionally do descriptions comprise, apart from cytoplasmic and nuclear features, architectural Architectural arrangement cells specimens, however, may mirror corresponding provided preparations collected prepared appropriately. Recognition understanding different types cell that be seen can provide important information for...
Abstract: A 9‐year‐old female spayed mixed‐breed dog was presented to the referring veterinarian with a history of decreased appetite and difficulty prehension swallowing because firm oval mass in tongue. On cytologic evaluation fine‐needle aspirate there were numerous round polygonal cells organized individually or loose clusters rare branching capillaries. The had eosinophilic granular cytoplasm, nuclei, occasionally indistinct borders. diagnosis cell tumor (GCT) Impression smears biopsy...
Summary A 12‐year‐old intact female mixed breed dog was presented for chronic, intermittent vomiting and diarrhoea. On endoscopic examination a protruding mass arising from the mucosal surface of pyloric region detected. Cytological histological revealed an accumulation pleomorphic round/oval phagocytic cells suggesting histiocytic origin. This confirmed by immunohistochemistry. No extra‐gastric involvement detected on clinical or at necropsy. is first report primary gastric sarcoma in dog.
The increased sophistication of imaging techniques in veterinary medicine allows the detection a wide variety intracranial and intraspinal lesions; however, often does not provide definitive diagnosis for nervous system (NS) lesions. Cytology is emerging as useful diagnostic tool obtaining fast accurate assessment NS lesions, but little information available dogs cats.The purpose this study was to assess accuracy cytologic evaluation squash samples from lesions cats consider cytology-based...
Percutaneous fine-needle biopsy was used to investigate thoracic and abdominal masses in the dog cat. One hundred thirty-two cases were included study; 20 excluded from comparative study due poor cellularity or blood contamination (retrieval rate 86.8 per cent). samples (56 dogs 44 cats) classified by cytology as neoplastic. All cytological diagnoses of neoplasia confirmed histological obtained either non-surgical methods, at surgery during postmortem examination. No false positive made....
Bronchoalveolar lavage (BAL) allows cell recovery from the lower respiratory tract; differential counts of BAL fluid gives important information in assessment various bronchial and pulmonary diseases. To best our knowledge no study has investigated relation between number cells counted reproducibility counts.The purpose this was to investigate using statistical methods how many should be cytocentrifuged preparations order obtain a reliable enumeration each type.BAL samples dogs with...
Introduction Liver cytology has diagnostic value for the identification of neoplastic and nonneoplastic hepatic diseases. However, so far diagnosis fibrotic changes traditionally been restricted to histopathology. Objectives The aim this study was describe cytologic features that may help in recognition fibrosis. Materials methods Cytologic smears from liver dogs histologically diagnosed with fibrosis (Group A) were selected compared without B). A differential count hepatocytes, spindle...
Cytopathology is a minimally invasive and convenient diagnostic procedure, often used as substitute for histopathology to diagnose characterize lymphoma in dogs. Assess the performance of cytopathology diagnosing its histopathological subtypes One-hundred sixty-one lymph node samples from 139 dogs with enlarged peripheral nodes. Based only on cytopathology, 6 examiners independently provided following interpretations each sample: (a) vs nonlymphoma; (b) grade phenotype; (c) World Health...
Abstract: A 14‐year‐old Italian Griffon and an 11‐year‐old mixed breed dog were presented to our clinic with monolateral testicular enlargement. In both dogs, a firm, nodular, nonpainful mass was palpated, ultrasonographic examination of parenchyma showed large irregular nodular area hyperechogenic features. Fine‐needle aspirates the masses highly cellular consisted populations elongated vacuolated cells in sheets palisades, finely granular chromatin prominent nucleoli, consistent neoplastic...
Although the presence of mast cells is considered a normal finding in canine hepatic tissue, proportion these cytologic specimens from livers was not previously established.The objective this study to determine liver by use and comparison May-Grünwald-Giemsa Toluidine Blue staining methods.The obtained fine-needle aspirates 13 healthy dogs were investigated counting hepatocytes per high-power field (HPF, x40 objective). The ratio cells/100 then compared between 2 methods.A median 0.17...
Canine cutaneous mast cell tumours (MCTs) have a variable biologic behaviour, and accurate staging is necessary to dictate therapy predict outcome. Regional lymph node (RLN) involvement relevant prognostic factor. While obvious (LN) metastases are relatively easy be diagnosed, micrometastatic disease recognition challenging. The main aim of the study was evaluate number cells (MCs) in LNs clinically healthy dogs (n = 4, group 1), with inflammatory diseases 31, 2) MCT 27, 3), including...
Background Cytologic evaluation plays an important role in the diagnosis of ovarian neoplasia dogs, but is supported by only scant information on cytologic features canine ovaries. Objective The aim this study was to provide detailed descriptions normal ovaries different stages estrus with comparison histologic features. Methods Client‐owned dogs admitted for elective ovariohysterectomy were studied. For each dog, fine‐needle aspirates both collected, stained, and examined compared sections...
Abstract Background Histologic examination, together with clinical data and instrument support, contributes to the recognition of biliary diseases. Although quantitative qualitative changes in hepatic cells can occur, descriptions cytologic samples from liver affected by cholangiopathies are rare. Objectives This study aimed describe cholangiocytes, hepatocytes, inflammatory dogs cats histologically confirmed cholangiopathies. Methods Cytologic were reviewed compared seen on cytology. The...
Objectives The aim of this study was to investigate the role thyroid transcription factor-1 (TTF-1) in diagnosis feline lung-digit syndrome (FLDS) and associations between morphological features FLDS TTF-1 expression. We also compared reliability transmission electron microscopy (TEM) establishing FLDS. Methods Histology records digit tumours were retrieved, including patients from 2008-2015. If formalin-fixed, paraffin-embedded tissues available for review, included study. As a control...
Background — Fine needle aspiration cytology is being used for the diagnosis of various neoplasms, but we are unaware reports dealing with cytologic features canine pilomatricoma. Objective The purpose this report was to describe pilomatricoma in 3 dogs. Methods Fine‐needle aspirates were obtained from cutaneous masses using a 25‐ga needle. Smears prepared and stained May‐Grünwald‐Giemsa hematoxylin eosin. excised routinely processed histologic examination. Results Cytologic all tumors...