A5019887285- Melanoma and MAPK Pathways
- Abdominal vascular conditions and treatments
- Cutaneous Melanoma Detection and Management
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Appendicitis Diagnosis and Management
- Abdominal Trauma and Injuries
- Uterine Myomas and Treatments
- Cancer, Hypoxia, and Metabolism
- Immunotherapy and Immune Responses
- Chronic Lymphocytic Leukemia Research
- Trauma and Emergency Care Studies
- Acute Ischemic Stroke Management
- CAR-T cell therapy research
- Cancer Research and Treatments
- Abdominal Surgery and Complications
- Intraperitoneal and Appendiceal Malignancies
- Adrenal and Paraganglionic Tumors
- Endometriosis Research and Treatment
- Aortic aneurysm repair treatments
- Advanced Breast Cancer Therapies
- Nonmelanoma Skin Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Gynecological conditions and treatments
- Spinal Hematomas and Complications
University of North Carolina at Chapel Hill
2024
The University of Texas MD Anderson Cancer Center
2020-2023
Guthrie Robert Packer Hospital
2017-2019
SUNY Upstate Medical University
2017-2019
Guthrie Foundation
2019
Caribbean University
2019
University of Abuja
2019
Howard University
2019
St. Bonaventure University
2019
Commonwealth Medical College
2017-2018
Bacteria were first detected in human tumors more than 100 years ago, but the characterization of tumor microbiome has remained challenging because its low biomass. We undertook a comprehensive analysis microbiome, studying 1526 and their adjacent normal tissues across seven cancer types, including breast, lung, ovary, pancreas, melanoma, bone, brain tumors. found that each type distinct composition breast particularly rich diverse microbiome. The intratumor bacteria are mostly intracellular...
Rectal foreign bodies are a common presenting complaint in the emergency department. Anal eroticism is major reason for majority of cases rectal bodies. A high index suspicion required to accurately diagnose body as patients often embarrassed about their condition and may not present timely fashion be evaluated or volunteer history. Extraction techniques include transanal, endoscopic, laparotomy with repair complications. Here, we case successful transanal manual removal retained dumbbell...
Gallstone spillage is a common intraoperative event during laparoscopic cholecystectomy (LC). Patients present months to years with nonspecific symptoms after the original procedure. The complications of retained peritoneal gallstones are infrequent. Having high index suspicion key early diagnosis. Every effort should be made remove spilled at operation prevent future complications, however, conversion from laparoscopy laparotomy for retrieval spilt gallstone not recommended. Here we case...
10067 Background: Metastatic melanoma pt outcomes have been revolutionized by targeted therapy (TT) and immune checkpoint blockade (ICB), which are now being evaluated in the neoadjuvant (neoadj) setting. While tumor-based biomarkers may help predict response, predictors of response obtained less invasive strategies could greatly benefit care allow real-time treatment monitoring. Radiomic signatures derived from computerized tomography (CT) images recently shown to ICB stage IV pts. However,...
Endometriosis is characterized by the growth of endometrial tissue outside uterine cavity. appendix rare and its preoperative diagnosis difficult. We report case a postmenopausal woman who presented with right lower quadrant abdominal pain concerning for acute appendicitis. Histopathological examination her revealed endometriosis resolved after appendectomy.
A double caecal appendix is an uncommon anatomical variation with significant surgical implications. few cases of the have been reported worldwide, mostly in adults. The diagnosis is, usually incidental, typically made intraoperatively. We present case a 6-month-old boy incidental during laparotomy for intussusception. can be classified using Cave-Wallbridge classification, which identifies three types duplicated appendix: A, B, and C. complication appendiceal duplications includes acute...
Clostridium perfringens (CP) bacteremia is a rare but rapidly fatal infection. Only 36 cases of CP with gas containing liver abscesses on image studies have been reported in the literature since 1990. In this report, we describe 65-year-old diabetic male which progressed into fulminant hepatic failure subsequent cerebral edema.
Celiac artery compression syndrome is an anatomic of the celiac axis by median arcuate ligament. Patients often present with postprandial pain, as well symptoms gastroparesis. It usually a diagnosis exclusion. The treatment aimed at relieving artery, and neurolysis. We case 55-year-old woman treated laparoscopic decompression
Endometriosis is a pathological condition whereby endometrial glands and stroma are located outside the physiologically expected location, uterus. A lesion usually in pelvis but can also occur diaphragm, bowel, pleural cavity, or surgical scar. It benign estrogen-dependent condition. Here, we present case of 40-year-old woman with ectopic endometriosis.
Pheochromocytomas are rare tumors derived from chromaffin cells located in the adrenal and extra tissues. diagnosed biochemically localized using different imaging modalities. The definitive management is surgical resection. Brown adipose tissues normally present during fetal development, with regression over time. thermogenic usually neck, mediastinum, retroperitoneum. Here, we report a case of unilateral pheochromocytoma surrounded by brown fat. abnormal stimulation fat noted on positive...
We present a case of left upper extremity paresis secondary to acute brachial artery occlusion in an elderly female with active non-ST segment elevation myocardial ischemia (NSTEMI) the setting paroxysmal atrial fibrillation. The patient was initially suspected have cerebrovascular attack (CVA); however, computed tomography (CT) head negative for stroke. diagnosis confirmed by tomographic angiography (CTA) extremity, confirming occlusion. In evaluating concern stroke atypical presentation,...
Anal melanoma is a rare and aggressive neoplasm of the anal canal seen in elderly population six or seventh decade their lives. Presentation usually nonspecific diagnosis often delayed missed initially. The management surgical prognosis poor. Here we present case an patient masquerading as hemorrhoid.
We present a case of giant abdominal aortic aneurysm greater than 17 cm complicated by an endoleak, demonstrating the natural history untreated Type 1 endoleak.
Giant pheochromocytomas (Pheo) are rare entities requiring clinical suspicion coupled with strategic diagnostic evaluation to confirm the diagnosis. The majority of cases discovered incidentally. diagnosis consists biochemical and imaging study localize mass. Pathological examination confirms female patient in this case report presented chest pain, palpitation three weeks duration was found on have an abdominal mass concerning for pheochromocytoma. She treated surgical resection. pheo...
Severe acute respiratory distress syndrome after laparoscopic appendectomy for appendicitis in a young adult is an uncommon complication. We describe the case of 25-year-old male who developed severe uneventful perforated appendix, requiring mechanical ventilation intensive care unit.
Introduction:The extremities are the most common area of body to be injured from gunshot wounds (GSWs).If there no vascular or orthopedic injuries, an operation is typically not indicated.As a bullet travels through tissue, it only creates cavity but also vacuum both as enters and exits.This allows debris enter tissue contaminate wound.We hypothesize that non-operative wound caused by traveling layers clothing will have higher infection rate than did travel clothing. Methods:Patients who...
BACKGROUND Early administration of plasma improves mortality in massively transfused patients, but the thawing process causes delay. Small rural centers have been reluctant to maintain thawed due waste concerns. Our 254-bed Level II trauma center initiated a protocol allowing continuous access plasma, and we hypothesized its implementation would not increase or cost. METHODS Two units are continuously maintained bay blood refrigerator. After 3 days, these replaced with freshly returned bank...