- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Cardiac tumors and thrombi
- Cardiac Structural Anomalies and Repair
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Long-Term Effects of COVID-19
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Climate Change and Health Impacts
- Stroke Rehabilitation and Recovery
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- Dermatological and COVID-19 studies
- Diabetes Treatment and Management
- Cerebral Venous Sinus Thrombosis
- Blood Coagulation and Thrombosis Mechanisms
- Potassium and Related Disorders
National University Hospital
2020-2025
National University of Singapore
2018-2024
National University Health System
2020-2024
National University Heart Centre Singapore
2024
Singapore General Hospital
2022
Singapore College of Traditional Chinese Medicine
2018
Background and aimCOVID-19 pandemic has resulted in an unprecedented increased usage of Personal protective equipment (PPE) by healthcare-workers. PPE causes headache majority users. We evaluated changes cerebral hemodynamics among healthcare-workers using PPE.MethodsFrontline donning at our tertiary center were included. Demographics, co-morbidities blood-pressure recorded. Transcranial Doppler (TCD) monitoring middle artery was performed with 2-MHz probe. Mean flow velocity (MFV)...
<b><i>Introduction:</i></b> It is unclear which surrogate of atrial cardiopathy best predicts the risk developing a recurrent ischemic stroke in embolic undetermined source (ESUS). Left diameter (LAD) and LAD index (LADi) are often used as markers left enlargement current ESUS research, but volume (LAVi) has been found to be better predictor cardiovascular outcomes other patient populations. <b><i>Objective:</i></b> We aim compare performance...
Intravenous tissue plasminogen activator (tPA) remains the cornerstone of recanalization therapy for acute ischemic stroke (AIS), albeit with varying degrees response. The triglyceride-glucose (TyG) index is a novel marker insulin resistance, but association outcomes among AIS patients who have received tPA has not been well elucidated. We studied 698 from 2006 to 2018 in comprehensive centre. TyG was calculated using formula: ln[fasting triglycerides (mg/dL) × fasting glucose (mg/dL)/2]....
Background: Severe aortic stenosis (AS) stratified by sex has been increasingly studied in the European population. Sex-specific outcomes Asian patients with AS remain poorly defined. Hence, we aimed to study clinical characteristics and impact of moderate-to-severe AS, undergoing both invasive conservative interventions an cohort over 10 years. Methods: Consecutive data echocardiographic diagnoses were according gender a tertiary academic center between 2011 2021. Demographics,...
Transient hyperglycaemia in the context of illness with or without known diabetes has been termed as 'stress hyperglycaemia'. Stress can result poor functional outcomes patients acute ischaemic stroke (AIS) who underwent mechanical thrombectomy. We investigated association between stress and clinical AIS undergoing intravenous thrombolysis (IVT).We examined 666 consecutive IVT from 2006 to 2018. All had a glycated haemoglobin level (HbA1c) fasting venous blood glucose measured within 24 h...
Several P-wave indices are thought to represent underlying atrial remodeling and have been associated with ischaemic stroke even in the absence of fibrillation (AF). However, utility these predicting outcomes patients embolic undetermined source (ESUS) has not studied. The aim this study is examine different towards new-onset AF recurrence a cohort ESUS, thereby demonstrating value electrocardiographic markers for risk stratification.Between October 2014 2017, consecutive diagnosed ESUS were...
frailty has been shown to be a better predictor of clinical outcomes than age alone across many diseases. Few studies have examined the relationship between frailty, stroke and interventions such as endovascular thrombectomy (EVT).we aimed investigate impact measured by scale (CFS) on after EVT for acute ischemic (AIS) in older patients ≥70 years.in this retrospective cohort study, we included all consecutive AIS ≥ 70 years receiving at single comprehensive centre. Patients with CFS 1-3 were...
The role of bridging intravenous thrombolysis (IVT) before endovascular thrombectomy (EVT) in the treatment acute ischemic stroke (AIS) remains debatable. Atrial fibrillation (AF) associated strokes may be with reduced effect from IVT. This study compares IVT AF and non-AF patients.