A5045568560- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Heart Failure Treatment and Management
- Hemodynamic Monitoring and Therapy
- Atrial Fibrillation Management and Outcomes
- Aortic Disease and Treatment Approaches
- Cardiac pacing and defibrillation studies
- Cardiovascular and Diving-Related Complications
- Cardiovascular Health and Disease Prevention
- Congenital Heart Disease Studies
- COVID-19 and healthcare impacts
- Cardiovascular Effects of Exercise
- Radiation Dose and Imaging
- Tracheal and airway disorders
- Ultrasound in Clinical Applications
- Cardiac Structural Anomalies and Repair
- Pericarditis and Cardiac Tamponade
- Cerebrovascular and Carotid Artery Diseases
- Trauma Management and Diagnosis
- Vascular Anomalies and Treatments
- COVID-19 Clinical Research Studies
- Airway Management and Intubation Techniques
Vita-Salute San Raffaele University
2023-2025
Mylan (Switzerland)
2024-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2025
Mylan (South Africa)
2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2023-2024
San Raffaele University of Rome
2023-2024
University of Milan
2023
IRCCS Ospedale San Raffaele
2023
IRCCS Policlinico San Donato
2019-2022
Istituto Clinico Sant'Ambrogio
2022
Transcatheter aortic valve replacement (TAVR) is an effective treatment option for patients with severe, symptomatic AS, regardless of the transcatheter heart (THV) implanted. Prior studies demonstrated a higher device success lower paravalvular leak (PVL) using balloon-expandable (BE) Sapien/XT THV vs. self-expanding (SE) THV. However, few data are available on performance novel BE
Abstract Background Global Longitudinal Strain (GLS) and left atrial (LA) strain evaluation by Speckle Tracking Echocardiography (STE) have emerged as prognostic index in patients affected degenerative mitral regurgitation (DMR). In this setting, the coupling between right ventricular (RV) function pulmonary circulation (PC) has demonstrated to be associated with cardiovascular outcome. However, prevalence of RV PC uncoupling undergoing surgery for DMR its relationship (LV) LA functioning...
The 2021 International Consensus for the congenital bicuspid aortic valve condition recognizes 3 morphologies of (fused, 2-sinus and partial-fusion) types aortopathy (ascending, root extended). clinical impact phenotyping on evolution has not been evaluated so far.The aims were to assess: 1) prevalence phenotypes; 2) frequency valve-related dysfunction aortopathy; 3) inter-phenotypic differences in progression a real-world population. This was an observational cohort study patients with...
Treatments for structural heart diseases (SHD) have been considerably evolved by the widespread of transcatheter approach in last decades. The progression treatments SHD was feasible due to improvement devices and advances imaging techniques. In this setting, cardiovascular is pivotal not only diagnosis but even treatment SHD. With aim fulfilling these tasks, a multimodality with new tools pre-procedural planning, intra-procedural guidance, follow-up developed. This review will describe...
Abstract Aims In acute heart failure (AHF), the consequences of impaired left atrial (LA) mechanics are not well understood. We aimed to define clinical trajectory LA by strain (LAS) analysis. Methods and results Eighty-five consecutive AHF patients with reduced, mildly preserved ventricular ejection fraction (LVEF) were enrolled in LAS-AHF trial underwent analysis speckle tracking echocardiography. Seventy-seven followed-up (FU) at 6 12 months. At hospital admission, discharge, months...
Santangelo, Gloria; Silvestro, Antonio; Medda, Massimo; Barki, Monica; Maliandi, Gabriele; Donatelli, Francesco; Tespili, Maurizio; Ielasi, Alfonso Author Information
The acquired communication between the aorta and pulmonary artery is a rare potentially life-threatening condition. Its diagnosis challenging may require multimodality imaging approach.
Abstract Background Bicuspid aortic valve (BAV) represents one of the most common congenital heart disease. BAV stenosis tipycally occurs in younger, low-surgical risk patients compared to tricuspid valves (TAV). With predicted expansion trans-catheter replacement (TAVR) into lower-risk patients, proportion is expected rise. Although some observational studies have investigated characteristics Asian versus European with undergoing TAVR, little known about inter-ethnic differences within...
Abstract Background Stroke volume (SV) is the net result of cardiac dynamics and functional capacity. Notably, acute decompensated heart failure (ADHF) patients admitted highly congested with a reduced SV (primarily wet cold phenotype) exhibit poorer prognosis. However, how may change in warm phenotype during hospital setting remains undefined. Purpose To evaluate, cohort ADHF patients, pattern changes hospitalization. Methods Eighty-one (mean age 75.75±10.6 years, 59% males) were...
Abstract Background A significant proportion of patients hospitalized for acute decompensated heart failure (ADHF) are readmitted to the hospital within 30 days, resulting in a major social and economic burden. Thus, risk stratification identification targets therapy is basic importance. Non-invasive imaging modality such as transthoracic echocardiography (TTE) represents cornerstone tool approach this clinical scenario early recognition high-risk patients. Purpose To define whether left...
Abstract Background Heart failure (HF) patients are categorized according to left ventricular ejection fraction (LVEF), being such index both easily feasible and prognostic. However, the risk stratification of hospitalized for acute decompensated heart (ADHF) absolute value LVEF at presentation is unexplored its prognostic significance has not been tested against stroke volume indexed (SVi). Purpose To examine impact SVi versus in ADHF (wet warm phenotype). Methods Eighty-five (mean age...
Abstract During COVID–19 pandemic, a critical issue for cardiologists was to provide early access the standard of care patients with time–dependent diseases such as ST–segment elevation myocardial infarction (STEMI), while making efforts prevent their exposure SARS CoV–2. Aims: The aim our research project evaluate role an Emergency Department–based operative unit directly managed by Cardiology Department in providing prompt cardiological evaluation STEMI at first medical contact, which we...
Abstract Funding Acknowledgements Type of funding sources: None. Background Understanding the pathophisiology symptoms onset in degenerative mitral regurgitation may be helpful management asymptomatic patients. Left atrium (LA) is far from simply being a passive connection chamber between valve and pulmonary circulation, role left atrial function as predictor has not yet been evaluated. The increase pressure that causes elevation capillary pressures dyspnoea driven by reduction compliance,...
Abstract Funding Acknowledgements Type of funding sources: None. Background Chronic severe degenerative mitral regurgitation (DMR) is a progressive disease with negative impact on prognosis and surgical repair or replacement represents the standard care. Recently, coupling between right ventricular (RV) function pulmonary circulation (Pc) emerged as prognostic index in patients undergoing transcatheter edge-to-edge repair. However, relationship circulatory uncoupling clinical outcomes...
Abstract Funding Acknowledgements Type of funding sources: None. Background The uncoupling right ventricular (RV) function to pulmonary circulation (Pc) represents a prognostic index in patients affected by degenerative mitral regurgitation (DMR) undergoing surgical or percutaneous repair. In this context, the deterioration Left Atrial (LA) dynamics favors development venous congestion and vascular remodeling, triggering hypertension (PH) dysfunction. However, relationship between LA...
Abstract Background The degree of congestion in patients hospitalized for acute decompensated heart failure (ADHF) is estimated using traditional non-invasive markers such as echo-derived inferior vena cava diameter (IVCD) and NT-proBNP levels. deterioration right ventricular (RV) function its uncoupling to pulmonary circulation (Pc) represents a turning point terms prognosis clinical outcome affected by failure. However, how RV-to-Pc correlates with decompensation ADHF has never been...