A5102891623- Veterinary Oncology Research
- Infectious Diseases and Mycology
- Virus-based gene therapy research
- Microbial infections and disease research
- Oral and Maxillofacial Pathology
- Veterinary Orthopedics and Neurology
- Cardiovascular Conditions and Treatments
- Veterinary Medicine and Surgery
- Platelet Disorders and Treatments
- Sarcoma Diagnosis and Treatment
- Blood groups and transfusion
- Cancer and Skin Lesions
- Lymphoma Diagnosis and Treatment
- Drug-Induced Adverse Reactions
- Zoonotic diseases and public health
- Research on Leishmaniasis Studies
- Bacillus and Francisella bacterial research
- Autoimmune Bullous Skin Diseases
- Inflammatory mediators and NSAID effects
- Venous Thromboembolism Diagnosis and Management
- Poxvirus research and outbreaks
- Chronic Lymphocytic Leukemia Research
- Trypanosoma species research and implications
- Cancer Research and Treatments
- Cancer, Stress, Anesthesia, and Immune Response
Corporació Sanitària Parc Taulí
2024
Royal Veterinary College
2010-2023
Deleted Institution
2023
University of London
2010-2020
The Ohio State University
2006-2013
Hokkaido University
2013
Cancer Clinic
2013
Veterinary Medical Teaching Hospital
2008
Virginia Commonwealth University
2008
Hospital Clínico Universitario de Caracas
2001
Background : Histiocytic sarcoma is an aggressive neoplasm of dendritic cells that carries a grave prognosis. The efficacy chemotherapy against this disease unknown. purpose study was to determine the 1‐(2‐chloroethyl)‐3‐cyclohexyl‐1‐nitrosourea (CCNU) in dogs with incompletely resected or metastatic histiocytic sarcoma, describe clinical characteristics these dogs, and identify factors affecting Hypothesis Our hypothesis CCNU has activity canine can improve survival advanced disease....
Background: Histiocytic sarcoma is an aggressive neoplasm of dendritic cells that carries a grave prognosis. The efficacy chemotherapy against this disease unknown. purpose study was to determine the 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in dogs with incompletely resected or metastatic histiocytic sarcoma, describe clinical characteristics these dogs, and identify factors affecting Hypothesis: Our hypothesis CCNU has activity canine can improve survival advanced disease....
Background : Various chemotherapy protocols for treating lymphoma in dogs have been published; however, comparison of from different studies is difficult, especially when evaluating survival time and toxicoses. Hypothesis The choice COAP (C, cyclophosphamide; O, vincristine; A, cytosine arabinoside; P, prednisone) a modified University Wisconsin 19‐week (UW‐19) induction protocol has no influence on overall times with lymphoma. Animals One hundred one multicentric Methods Retrospective study...
There is increased pressure by governments and industry to develop national surveillance programmes evaluate antimicrobial usage (AMU) in animals.This article presents a methodological approach cost-effectiveness analysis of such programmes.Seven objectives are proposed for AMU animals: quantifying use, finding trends, detecting hotspots, identifying risk factors, encouraging research, evaluating the impact policies diseases, demonstrating compliance with regulations.Achieving these would...
Some retired racing Greyhounds (RRG) that undergo surgery bleed excessively.Greyhounds excessively will have one or more preoperative hemostatic abnormalities can be used to predict the risk and severity of postoperative bleeding.Eighty-eight RRG undergoing ovariohysterectomy castration.All dogs were evaluated preoperatively with a physical exam, CBC, platelet count, OSPT, APTT, function PFA-100(a); fibrinogen, d-dimer, plasminogen (Plmg), antiplasmin (AP), antithrombin (AT), vWF...
Abstract Objectives To determine the frequency of delayed postoperative bleeding in retired racing G reyhounds with appendicular bone tumors undergoing limb amputations. identify if administration epsilon‐aminocaproic acid ( EACA ) was effective on prevention bleeding. Design Retrospective study from D ecember 2003 to 2008. Setting Veterinary university teaching hospital. Animals Forty‐six RRG s) diagnosed primary that underwent amputation were included study. Interventions None....
Canine lymphoma is a heterogeneous group of diseases and many previous studies have evaluated the response mixed population cases to one specific treatment protocol. The aim this retrospective study was describe outcome prognostic factors in 42 multicentric centroblastic diffuse large B‐cell treated with either COP‐type (35%) or CHOP‐type (64%) induction chemotherapy. objective rate therapy 94%; entire dogs had greater complete vs partial remissions than neutered ( P = .017). Median...
Introduction: Surgery is the main pilar for treatment of ovarian cancer patients. The improvement minimally invasive surgery (MIS) has led to its application a greater number processes. However, MIS still under debate, since behaviour and pattern spread make difficult assure proper with this approach. Our aim was evaluate advantages in management among young Materials Methods: A retrospective study conducted participation 55 Spanish hospitals. We included all patients aged between 18 45...
Hemangiosarcomas (HSAs) are aggressive tumors with a high rate of metastasis. Clinical stage has been considered negative prognostic factor for survival. The study authors hypothesized that the median survival time (MST) dogs metastatic (stage III) HSA treated vincristine, doxorubicin, and cyclophosphamide (VAC) chemotherapy protocol would not be different than those I/II HSA. Sixty-seven in anatomic locations were evaluated retrospectively. All received VAC as an adjuvant to surgery (n =...
The cancer microenvironment plays a pivotal role in oncogenesis, containing number of regulatory cells that attenuate the anti-neoplastic immune response. While negative prognostic impact T (Tregs) context most solid tissue tumors is well established, their lymphoid malignancies remains unclear. expressing FOXP3 and Helios were documented fine needle aspirates affected lymph nodes dogs with spontaneous multicentric B cell lymphoma (BCL), proposed to be model for human non-Hodgkin lymphoma....
As the resolution of noninvasive neuroimaging techniques improves, small structures such as mamillary bodies can be visualized and measured. The are pathologically in a number neurological disorders, most common important is chronic Wernicke's encephalopathy (WE), or Wernicke-Korsakoff syndrome (WKS), it often called. This disorder caused by vitamin B1 deficiency (thiamin) seen commonly people who drink excessive amounts alcohol. easily preventable using oral parenteral thiamin. aim this...
Oral administration of low-dose cyclophosphamide in pets with spontaneously occurring malignant neoplasms has become a common practice veterinary medicine. The purpose this retrospective study was to investigate toxicity events cats spontaneous malignancies receiving as metronomic therapy for at least 1 month. number and severity clinical, haematological biochemical adverse were recorded according the Veterinary Cooperative Oncology Group’s Common Terminology Criteria Adverse Events v1.1...
The use of adjuvant 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; lomustine) to treat incompletely excised canine mast cell tumors (MCTs) has not been evaluated. Medical records 12 dogs with grade 2 MCT treated incomplete surgical excision and CCNU prednisone chemotherapy were reviewed. Local recurrence rate, metastasis survival time None the developed local or regional/ distant metastases. Two fatal liver failure. 1- 2-year progression-free rates surviving 100% 77%, respectively....
There is little published information on the ultrasonographic appearance of canine renal lymphoma. The purpose this retrospective study was to provide additional regarding characteristics lymphoma, suggest description criteria, and evaluate role fine‐needle aspirate cytology in diagnosis disease. features confirmed lymphoma were reviewed ten dogs. Pyelectasia found all Other findings loss corticomedullary distinction (9/10 dogs), renomegaly (8/10 deformity (6/10 hypoechoic lesion(s)...
The purpose of this study was to evaluate prevalence serum alanine transaminase (ALT) elevation in dogs receiving lomustine (CCNU) and analyse the pattern occurrence potential risk factors. Serum ALT activity 109 during single-agent CCNU chemotherapy retrospectively analysed. median initial dose, dose-intensity cumulative dose were 64 mg m(-2), 21 m(-2) week(-1) 171 respectively. overall major [> 5-fold upper reference limit (URL)] 29% (32/109) developed most commonly after one three doses...
Limited veterinary literature is available regarding prognostic markers for canine renal cell carcinoma (CRCC). We retrospectively evaluated COX-2 expression, histological and clinical features associated with prognosis of CRCC. Sixty-four cases post-nephrectomy were included, 54 had histopathological assessment 30 immunostaining performed. Eight dogs (13%) metastatic disease at initial diagnosis. Twenty-seven (42%) received adjuvant therapy after nephrectomy. On univariate analysis, mitotic...
Objectives Feline primary laryngeal or tracheal lymphoma (PLTL) is an uncommon extranodal presentation. Information on long-term survival scarce, although some small case series describe this being achieved with multiagent protocols; accurate outcome for cats PLTL yet to be determined. The aim of study was gather information the clinical presentation, response treatment and in a large feline PLTL. Methods This retrospective multicentre included cytological histopathological confirmation...
Veterinarians involved in Greyhound rescue have anecdotally observed that 10-15% of Greyhounds bleed profusely after simple surgical procedures. In most patients, platelet counts and hemostasis profiles are normal; therefore, it is possible these dogs dysfunction. The PFA-100 a novel point-of-care function analyzer has recently been evaluated as rapid method to assess dogs. objectives this study were characterize group healthy by means the PFA-100. Blood samples collected from jugular vein...
Abstract The objective of this multicentre retrospective study was to describe clinical presentation, treatment and outcome determine prognostic factors for dogs with presumed primary colorectal lymphoma ( PCRL ). A total 31 were included. predominant features high grade n = 18) immunophenotype B 24). Most substage b 25) higher prevalence haematochezia 20). One dog had surgery only. Thirty received chemotherapy; amongst them 13 or radiotherapy. Progression free survival PFS ) 1318 days...
Abstract Canine lymphoma, as the most common haematopoietic malignancy, encompasses a group of heterogeneous diseases and even within T‐cell immunophenotype, differences in clinical presentation responses to treatment exist. The aim this retrospective study was determine outcomes prognostic factors 107 dogs with multicentric non‐indolent lymphoma (TCL) receiving lomustine‐based (70%) non‐lomustine‐based (30%) treatment. majority were Labradors, Boxers, mixed‐breed Dogue de Bordeaux....
An 11-year-old female spayed domestic shorthair cat was referred to The Ohio State University Veterinary Teaching Hospital (OSU-VTH) for evaluation of a 6 x 4 3.5 cm mass in the left midcervical region causing increased respiratory sounds and lateral deviation trachea. A fine needle aspirate obtained before referral cytology results were compatible with reactive lymph node. Immunocytochemistry showed numbers CD3+ T lymphocytes small CD20+ CD79a+ medium large lymphocytes. Differential...